Antibody Data Sheet (Back to listing)
Price: $299.00 
| Product | Anti-Human P-Glycoprotein (P-gp) |
|---|---|
| Catalog # | 03-57043 |
| Amount | 100 µl |
| CATEGORY | Mouse monoclonal |
| CLONE DETERMINATION | JSB-1 |
| IMMUNOGLOBULIN CLASS | IgG1 |
| IMMUNOGEN | Human P-gp |
| FORM | Culture Supernatant |
| DESCRIPTION/SPECIFICITY | Mab JSB-1 reacts with a conserved cytoplasmic epitope of the plasma membrane-associated P-glycoprotein, a 170 kD multidrug resistance- related protein. It detects P-gp overexpression in human tumor cells of all different histogenetic origins |
| APPLICATION | Immunostaining of cell suspension and cytospin preparations Immunohistochemistry of frozen tissue, and paraffin- embedded tissue sections after microwave treatment (B-5 fixation) Flow Cytometry (cell permrabilization required) Immunoblotting (western) |
| ANTIGEN RECOGNIZED IN SPECIES (tested so far) | Human, Chinese hamster; no cross-reaction with rat and mouse |
| WORKING DILUTION | 1:20 for ICH and 1:10 for FACS |
| REFERENCES | Scheper RJ. et al. (1988) Int. J. Cancer 42: 389-394 Dalton, TM. et al. J. Clin. Oncology, Vol. 7, 4: 415-424 |
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