Specification Sheet

Pos	No.	Sex	Age	Organ	Pathology diagnosis	Grade	TNM	Image
A1	1	M	48	Thyroid	Normal			Image
A2	2	F	32	Thyroid	Normal			Image
A3	3	F	30	Thyroid	Diffuse toxic goiter			Image
A4	4	F	39	Thyroid	Diffuse toxic goiter			Image
A5	5	F	19	Thyroid	Diffuse toxic goiter			Image
B1	6	M	23	Thyroid	Diffuse nontoxic goiter			Image
B2	7	F	26	Thyroid	Diffuse nontoxic goiter			Image
B3	8	M	16	Thyroid	Diffuse nontoxic goiter*			Image
B4	9	F	50	Thyroid	Hashimoto's thyroiditis			Image
B5	10	F	49	Thyroid	Multi-nodular goiter			Image
C1	11	M	54	Thyroid	Multi-nodular goiter			Image
C2	12	M	56	Thyroid	Multi-nodular goiter			Image
C3	13	M	53	Thyroid	Adenoma			Image
C4	14	F	42	Thyroid	Adenoma			Image
C5	15	F	32	Thyroid	Adenoma			Image
D1	16	F	45	Thyroid	Papillary adenocarcinoma	I~II	T3N0M0	Image
D2	17	F	24	Thyroid	Papillary adenocarcinoma	II~III	T2N1M0	Image
D3	18	F	42	Thyroid	Papillary adenocarcinoma		T2N0M0	Image

* indicates the sample was from autopsy

† For precise diagnosis, refer to pathology description.

**The grade 1-3 (or I-III) in Pathology Diagnosis is equivalent to well-differentiated, moderately-differentiated or poorly differentiated, respectively, under microscope.
Grade 1 or well-differentiated: Cells appear normal and are not growing rapidly.
Grade 2 or moderately-differentiated: Cells appear slightly different than normal.
Grade 3 or poorly differentiated: Cells appear abnormal and tend to grow and spread more aggressively.
Grade 4 or undifferentiated: *(for certain tumors), features are not significantly distinguishing to make it look any different from undifferentiated cancers which occur in other organs.

TNM grading:

T - Primary tumor
Tx - Primary tumor cannot be assessed
T0 - No evidence of primary tumor
Tis - Carcinoma in situ; intraepithelial or invasion of lamina propria
T1 - Tumor invades submucosa
T2 - Tumor invades muscularis propria
T3 - Tumor invades through muscularis propria into subserosa or into non-peritonealized pericolic or perirectal tissues.
T4 - Tumor directly invades other organs or structures and/or perforate visceral peritoneum

N - Regional lymph nodes
Nx - Regional lymph nodes cannot be assessed
N0 - No regional lymph node metastasis
N1 - Metastasis in 1 to 3 regional lymph nodes
N2 - Metastasis in 4 or more regional lymph nodes

M - Distant metastasis
Mx - Distant metastasis cannot be assessed
M0 - No distant metastasis
M1 - Distant metastasis