US Biomax, Inc.


Thyroid disease spectrum tissue array, including TNM, clinical stage, 20 cases/ 20 cores

Microarray Panel:Thyroid disease spectrum tissue microarray, containing 3 cases of papillary carcinoma, 2 follicle carcinoma, 3 adenoma, 3 nodular goiter, 3 toxic goiter, 3 nontoxic goiter, 1 Hashimoto's thyroiditis , 2 cancer adjacent normal thyroid tissue, single core per case
Layout:5 cols × 4 rows
Core Diameter:2 mm
Thickness:5 µm

Routine histology procedures including Immunohistochemistry (IHC) and In Situ Hybridization (ISH), protocols which can be found at our support page.

Notes:1. TMA slides were sectioned and stored at 4°C and may not be fresh cut, but still suitable for IHC. Please request fresh cut if experiment involves phospho-specific antibodies, RNA studies, FISH or ISH, etc. A minimum of 3 slides per TMA must be purchased to cover the cost of trimming for fresh sectioning.
2. Most of the TMA slides were not coated with an extra layer of paraffin (tissue cores can be easily seen on the glass). We still recommend 30 minutes of baking at 60°C before putting into xylene for de-paraffinization procedure.

Microarray Panel Display

Slide Label: US Biomax, Inc. Tissue Array
A Thr Thr Thr Thr Thr  
B Thr Thr Thr Thr Thr  
C Thr Thr Thr Thr Thr  
D Thr Thr Thr Thr Thr Marked point
Legend: Thr - Thyroid

- Benign tumor, - Hyperplasia, - Inflammation, - Malignant tumor, - Malignant tumor (stage I), - Malignant tumor (stage II), - Malignant tumor (stage IVC), - Normal tissue

Specification Sheet

Pos No. Sex Age Organ Pathology diagnosis Stage TNM Type †
A1 1 F 48 Thyroid Papillary carcinoma II T2N0M0 Malignant
A2 2 F 30 Thyroid Papillary carcinoma II T2N0M0 Malignant
A3 3 F 24 Thyroid Papillary carcinoma I T3N0M0 Malignant
A4 4 F 63 Thyroid Follicle carcinoma IVC T4N0M1 Malignant
A5 5 F 49 Thyroid Follicle carcinoma IVC T3N0M1 Malignant
B1 6 F 39 Thyroid Fetal thyroid adenoma Benign
B2 7 M 26 Thyroid Adenoma with hemorrhage Benign
B3 8 F 27 Thyroid Adenoma Benign
B4 9 F 60 Thyroid Nodular goiter Hyperplasia
B5 10 F 40 Thyroid Nodular goiter Hyperplasia
C1 11 F 40 Thyroid Nodular goiter Hyperplasia
C2 12 F 41 Thyroid Toxic goiter Hyperplasia
C3 13 F 44 Thyroid Toxic goiter Hyperplasia
C4 14 F 32 Thyroid Toxic goiter Hyperplasia
C5 15 F 35 Thyroid Nontoxic goiter Hyperplasia
D1 16 M 38 Thyroid Nontoxic goiter Hyperplasia
D2 17 F 23 Thyroid Nontoxic goiter Hyperplasia
D3 18 F 45 Thyroid Chronic lymphocytic thyroiditis Inflammation
D4 19 M 22 Thyroid Normal thyroid tissue Normal
D5 20 F 15 Thyroid Normal thyroid tissue Normal
M 42 Adrenal gland Pheochromocytoma (tissue marker) Malignant

† For precise diagnosis, refer to pathology description.

TNM grading:

T - Primary tumor
Tx - Primary tumor cannot be assessed
T0 - No evidence of primary tumor
Tis - Carcinoma in situ; intraepithelial or invasion of lamina propria
T1 - Tumor invades submucosa
T2 - Tumor invades muscularis propria
T3 - Tumor invades through muscularis propria into subserosa or into non-peritonealized pericolic or perirectal tissues.
T4 - Tumor directly invades other organs or structures and/or perforate visceral peritoneum

N - Regional lymph nodes
Nx - Regional lymph nodes cannot be assessed
N0 - No regional lymph node metastasis
N1 - Metastasis in 1 to 3 regional lymph nodes
N2 - Metastasis in 4 or more regional lymph nodes

M - Distant metastasis
Mx - Distant metastasis cannot be assessed
M0 - No distant metastasis
M1 - Distant metastasis

Find overlapping cases with this tissue array: