|
| |
|
PR953
Prostate cancer tissue array with matched normal adjacent tissue and metastatic bones, with TNM, Gleason scores, PSA level and survival data, 40 cases/95 cores, replacing PR952
|
|
| Microarray Panel: | Prostate adenocarcinoma tissue microarray, duplicated cores, 36 cancer and 8 of which has matched normal adjacent tissue and 3 cases of metastasis in bones and 1 in abdominal wall,with follow-up data |
| Cores: | 95 |
|
| Cases: | 40 |
| Layout: | 12 cols × 8 rows |
| Core Diameter: | 1.5 mm |
| Thickness: | 5 µm | | Quality Control: | Anti-Actin confirmed | | Applications: | Routine histology procedures including ImmunoHistochemistry (IHC) and In Situ Hybridization (ISH), protocols which can be found on our support page. |
| Notes: | 1. Some slides are covered by a thin layer of paraffin to prevent oxidization and decay, thus are recommended be baked at 56-60°C up to 2 hours until the paraffin melt before doing regular IHC or ISH procedures. 2. For slides not coated with paraffin (those tissue cores can be easily seen on the glass), there is no need to bake, can be directly put into xylene for de-paraffin procedure. |
*Tissue Microarray Slide Types:
- Unstained: unstained
paraffin
tissue microarray slide.
- Trial: tissue microarray trial slide. 10% - 25% of cores missing. Good for titrating antibody dilution and experiment conditions. Limited numbers are available, to 2 per item per order. Test slides (tissue arrays with catalog numbers ending with 241 or 242) are recommended as a substitute.
- H & E: Hematoxylin and Eosin stained tissue microarray slide.
Specification Sheet
| Pos |
No. |
Sex |
Age |
Organ |
Pathology diagnosis |
Stage |
Gleason Score |
TNM |
Months |
Type † |
|
A1, A2 |
1 |
M |
68 |
Prostate |
Adenocarcinoma |
III |
9 |
T3bN0M0 |
. |
Malignant |
|
A3, A4 |
2 |
M |
64 |
Prostate |
Adenocarcinoma |
II |
7 |
T2cN0M0 |
. |
Malignant |
|
A5, A6 |
3 |
M |
71 |
Prostate |
Adenocarcinoma |
III |
9 |
T3bN0M0 |
. |
Malignant |
|
A7, A8 |
4 |
M |
64 |
Prostate |
Adenocarcinoma |
III |
10 |
T3aN0M0 |
. |
Malignant |
|
A9, A10 |
5 |
M |
59 |
Prostate |
Adenocarcinoma |
III |
9 |
T3bN0M0 |
. |
Malignant |
|
A11, A12 |
6 |
M |
65 |
Prostate |
Adenocarcinoma |
IV |
8 |
T4N0M0 |
. |
Malignant |
|
B1, B2 |
7 |
M |
73 |
Prostate |
Adenocarcinoma |
II |
7 |
T2cN0M0 |
. |
Malignant |
|
B3, B4 |
8 |
M |
69 |
Prostate |
Adenocarcinoma |
II |
7 |
T2cN0M1 |
. |
Malignant |
|
B5, B6 |
9 |
M |
62 |
Prostate |
Adenocarcinoma |
II |
7 |
T2cN0M1 |
. |
Malignant |
|
B7, B8 |
10 |
M |
66 |
Prostate |
Adenocarcinoma |
III |
9 |
T3bN0M0 |
. |
Malignant |
|
B9, B10 |
11 |
M |
60 |
Prostate |
Adenocarcinoma |
III |
9 |
T3bN0M0 |
. |
Malignant |
|
B11, B12 |
12 |
M |
70 |
Prostate |
Adenocarcinoma |
IV |
7 |
T4N0M0 |
. |
Malignant |
|
C1, C2 |
13 |
M |
65 |
Prostate |
Adenocarcinoma |
III |
9 |
T3bN0M1 |
. |
Malignant |
|
C3, C4 |
14 |
M |
67 |
Prostate |
Adenocarcinoma |
IV |
9 |
T3bN1M0 |
. |
Malignant |
|
C5, C6 |
15 |
M |
69 |
Prostate |
Adenocarcinoma |
III |
7 |
T3bN0M0 |
. |
Malignant |
|
C7, C8 |
16 |
M |
69 |
Prostate |
Adenocarcinoma |
III |
7 |
T3aN0M1 |
. |
Malignant |
|
C9, C10 |
17 |
M |
70 |
Prostate |
Adenocarcinoma |
III |
7 |
T3aN0M1 |
. |
Malignant |
|
C11, C12 |
18 |
M |
58 |
Prostate |
Adenocarcinoma |
III |
9 |
T3bN0M0 |
. |
Malignant |
|
D1, D2 |
19 |
M |
71 |
Prostate |
Adenocarcinoma |
II |
7 |
T2cN0M0 |
. |
Malignant |
|
D3, D4 |
20 |
M |
70 |
Prostate |
Adenocarcinoma |
III |
7 |
T3bN0M0 |
. |
Malignant |
|
D5, D6 |
21 |
M |
59 |
Prostate |
Adenocarcinoma |
II |
6 |
T2bN0M0 |
. |
Malignant |
|
D7, D8 |
22 |
M |
63 |
Prostate |
Adenocarcinoma |
III |
9 |
T3bN0M0 |
. |
Malignant |
|
D9, D10 |
23 |
M |
72 |
Prostate |
Adenocarcinoma |
III |
9 |
T3bN0M0 |
. |
Malignant |
|
D11, D12 |
24 |
M |
66 |
Prostate |
Adenocarcinoma |
III |
8 |
T3bN0M0 |
. |
Malignant |
|
E1, E2 |
25 |
M |
70 |
Prostate |
Adenocarcinoma |
II |
7 |
T2cN0M1 |
. |
Malignant |
|
E3, E4 |
26 |
M |
68 |
Prostate |
Adenocarcinoma |
III |
8 |
T3bN0M0 |
. |
Malignant |
|
E5, E6 |
27 |
M |
63 |
Prostate |
Adenocarcinoma |
III |
10 |
T3bN0M1 |
. |
Malignant |
|
E7, E8 |
28 |
M |
57 |
Prostate |
Adenocarcinoma |
III |
7 |
T3bN0M0 |
. |
Malignant |
|
E9, E10 |
29 |
M |
72 |
Prostate |
Adenocarcinoma |
III |
8 |
T2cN0M0 |
. |
Malignant |
|
E11, E12 |
30 |
M |
70 |
Prostate |
Adenocarcinoma |
III |
8 |
T3bN0M0 |
. |
Malignant |
|
F1, F2 |
31 |
M |
75 |
Prostate |
Adenocarcinoma |
III |
9 |
T3bN0M0 |
. |
Malignant |
|
F3, F4 |
32 |
M |
62 |
Prostate |
Adenocarcinoma |
III |
9 |
T3bN0M0 |
. |
Malignant |
|
F5, F6 |
33 |
M |
63 |
Prostate |
Adenocarcinoma |
III |
9 |
T3bN0M0 |
. |
Malignant |
|
F7, F8 |
34 |
M |
53 |
Prostate |
Adenocarcinoma |
III |
9 |
T3bN0M0 |
. |
Malignant |
|
F9, F10 |
35 |
M |
63 |
Prostate |
Adenocarcinoma |
III |
8 |
T3bN0M0 |
. |
Malignant |
|
F11, F12 |
36 |
M |
44 |
Prostate |
Adenocarcinoma |
III |
7 |
T3bN0M1 |
. |
Malignant |
|
G1, G2 |
37 |
M |
65 |
Abdominal wall |
Metastatic adenocarcinoma from prostate |
IV |
. |
M1 |
36 |
Metastasis |
|
G3, G4 |
38 |
M |
61 |
Bone |
Metastatic adenocarcinoma from prostate |
IV |
. |
M1 |
32 |
Metastasis |
|
G5, G6 |
39 |
M |
69 |
Bone |
Metastatic adenocarcinoma from prostate |
IV |
. |
M1 |
34 |
Metastasis |
|
G7, G8 |
40 |
M |
59 |
Bone |
Metastatic adenocarcinoma from prostate |
IV |
. |
M1 |
0 |
Metastasis |
|
G9, G10 |
41 |
M |
69 |
Prostate |
Normal (match of #8) |
. |
. |
. |
. |
NAT |
|
G11, G12 |
42 |
M |
62 |
Prostate |
Normal (match of #9) |
. |
. |
. |
. |
NAT |
|
H1, H2 |
43 |
M |
65 |
Prostate |
Normal (match of #13) |
. |
. |
. |
. |
NAT |
|
H3, H4 |
44 |
M |
69 |
Prostate |
Normal (match of #16) |
. |
. |
. |
. |
NAT |
|
H5, H6 |
45 |
M |
70 |
Prostate |
Normal (match of #17) |
. |
. |
. |
. |
NAT |
|
H7, H8 |
46 |
M |
70 |
Prostate |
Normal (match of #25) |
. |
. |
. |
. |
NAT |
|
H9, H10 |
47 |
M |
63 |
Prostate |
Normal (match of #27) |
. |
. |
. |
. |
NAT |
|
H11 |
48 |
M |
44 |
Prostate |
Normal (match of #36) |
. |
. |
. |
. |
NAT |
* Month, interval between primary and metastatic cancer
** TNM and stage, AJCC Cancer Staging Manual (6th Edition), pTNM, pathological TNM
† For precise diagnosis, refer to pathology description.
Supplementary Data
| Pos |
No. |
PSA (ng/ml) |
Residual tumor |
Follow-up months |
Follow-up result |
Cause of death |
Remark |
| A1, A2 |
1 |
. |
. |
. |
. |
. |
. |
| A3, A4 |
2 |
30 |
R0 |
60 |
alive |
. |
. |
| A5, A6 |
3 |
60.4 |
R1 |
55 |
alive |
. |
. |
| A7, A8 |
4 |
7.4 |
R1 |
47 |
alive |
. |
. |
| A9, A10 |
5 |
9.8 |
R1 |
44 |
alive |
. |
. |
| A11, A12 |
6 |
34.9 |
R1 |
43 |
alive |
. |
. |
| B1, B2 |
7 |
48.1 |
R1 |
42 |
alive |
. |
. |
| B3, B4 |
8 |
10.6 |
R0 |
42 |
alive |
. |
. |
| B5, B6 |
9 |
37.3 |
R1 |
39 |
alive |
. |
. |
| B7, B8 |
10 |
1.2 |
R1 |
39 |
alive |
. |
. |
| B9, B10 |
11 |
40 |
R1 |
39 |
alive |
. |
. |
| B11, B12 |
12 |
7 |
R1 |
37 |
alive |
. |
. |
| C1, C2 |
13 |
17.5 |
R1 |
23 |
dead |
cancer |
. |
| C3, C4 |
14 |
13.1 |
R1 |
34 |
alive |
. |
. |
| C5, C6 |
15 |
1.1 |
R1 |
33 |
alive |
. |
. |
| C7, C8 |
16 |
17.6 |
R1 |
27 |
alive |
. |
. |
| C9, C10 |
17 |
9 |
R1 |
26 |
alive |
. |
. |
| C11, C12 |
18 |
5.8 |
R0 |
26 |
alive |
. |
. |
| D1, D2 |
19 |
31.4 |
R1 |
24 |
alive |
. |
. |
| D3, D4 |
20 |
14.4 |
R1 |
19 |
alive |
. |
. |
| D5, D6 |
21 |
18.3 |
R0 |
18 |
alive |
. |
. |
| D7, D8 |
22 |
16.6 |
R1 |
17 |
alive |
. |
. |
| D9, D10 |
23 |
. |
R1 |
16 |
alive |
. |
. |
| D11, D12 |
24 |
10.8 |
R1 |
17 |
dead |
cancer |
. |
| E1, E2 |
25 |
. |
R0 |
15 |
alive |
. |
. |
| E3, E4 |
26 |
26.9 |
R1 |
15 |
alive |
. |
. |
| E5, E6 |
27 |
. |
R1 |
15 |
alive |
. |
. |
| E7, E8 |
28 |
25 |
R1 |
15 |
alive |
. |
. |
| E9, E10 |
29 |
16.8 |
R1 |
15 |
alive |
. |
. |
| E11, E12 |
30 |
0.5 |
R1 |
15 |
alive |
. |
. |
| F1, F2 |
31 |
98 |
R1 |
15 |
alive |
. |
. |
| F3, F4 |
32 |
. |
R1 |
15 |
alive |
. |
. |
| F5, F6 |
33 |
91 |
R1 |
14 |
alive |
. |
. |
| F7, F8 |
34 |
161 |
R1 |
17 |
dead |
cancer |
. |
| F9, F10 |
35 |
13 |
R1 |
13 |
alive |
. |
. |
| F11, F12 |
36 |
. |
R1 |
11 |
alive |
. |
. |
| G1, G2 |
37 |
. |
. |
. |
. |
. |
. |
| G3, G4 |
38 |
. |
. |
. |
. |
. |
. |
| G5, G6 |
39 |
. |
. |
. |
. |
. |
. |
| G7, G8 |
40 |
. |
. |
. |
. |
. |
. |
| G9, G10 |
41 |
. |
. |
. |
. |
. |
. |
| G11, G12 |
42 |
. |
. |
. |
. |
. |
. |
| H1, H2 |
43 |
. |
. |
. |
. |
. |
. |
| H3, H4 |
44 |
. |
. |
. |
. |
. |
. |
| H5, H6 |
45 |
. |
. |
. |
. |
. |
. |
| H7, H8 |
46 |
. |
. |
. |
. |
. |
. |
| H9, H10 |
47 |
. |
. |
. |
. |
. |
. |
| H11 |
48 |
. |
. |
. |
. |
. |
. |
TNM grading:
T - Primary tumor
Tx - Primary tumor cannot be assessed
T0 - No evidence of primary tumor
Tis - Carcinoma in situ; intraepithelial or invasion of lamina propria
T1 - Tumor invades submucosa
T2 - Tumor invades muscularis propria
T3 - Tumor invades through muscularis propria into subserosa or into non-peritonealized pericolic or perirectal tissues.
T4 - Tumor directly invades other organs or structures and/or perforate visceral peritoneum
N - Regional lymph nodes
Nx - Regional lymph nodes cannot be assessed
N0 - No regional lymph node metastasis
N1 - Metastasis in 1 to 3 regional lymph nodes
N2 - Metastasis in 4 or more regional lymph nodes
M - Distant metastasis
Mx - Distant metastasis cannot be assessed
M0 - No distant metastasis
M1 - Distant metastasis
|
|