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OR802
Oral cavity disease spectrum (oral cavity cancer progression) tissue array, 79 cases/80 cores
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| Microarray Panel: | Oral cavity disease spectrum (oral cavity carcinoma progression) tissue microarray, containing 28 cases of squamous cell carcinoma, 4 adenocarcinoma, 8 mucoepidermoid carcinoma, 2 basal cell carcinoma, 4 metastatic carcinoma, 8 adamantinoma, 6 hyperplasia, 5 each of adjacent tissue, inflammation, adjacent normal tissue and normal tissue, single core per case |
| Cores: | 80 |
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| Cases: | 79 |
| Layout: | 10 cols × 8 rows |
| Core Diameter: | 1.5 mm |
| Thickness: | 5 µm | | Quality Control: | Anti-Actin confirmed | | Applications: | Routine histology procedures including ImmunoHistochemistry (IHC) and In Situ Hybridization (ISH), protocols which can be found on our support page. |
| Notes: | Unless specified, all TMA slides are not coated with extra layer of paraffin (tissue cores can be easily seen on the glass), so there is no need to bake, can be directly put into xylene for de-paraffin procedure. |
*Tissue Microarray Slide Types:
- Unstained: unstained
paraffin
tissue microarray slide.
- Trial: tissue microarray trial slide. 10% - 25% of cores missing. Good for titrating antibody dilution and experiment conditions. Limited numbers are available, to 2 per item per order. Test slides (tissue arrays with catalog numbers ending with 241 or 242) are recommended as a substitute.
- H & E: Hematoxylin and Eosin stained tissue microarray slide.
Microarray Panel Display  | | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |
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| Legend: | Bas - Base of tongue,
Che - Cheek,
Den - Dental alveoli,
Gin - Gingiva,
Lef - Left mandible,
Lip - Lip,
Low - Lower lip,
Lym - Lymph node,
Man - Mandible,
Mou - Mouth floor,
Pal - Palate,
Par - Parotid gland,
Rig - Right cheek,
Roo - Root of tongue,
Sal - Salivary gland,
Sub - Submaxillary gland,
Ton - Tongue,
Upp - Upper lip
 - Adjacent,
 - Benign tumor,
 - Hyperplasia,
 - Inflammation,
 - Malignant tumor,
 - Malignant tumor (stage I),
 - Malignant tumor (stage II),
 - Malignant tumor (stage III),
 - Malignant tumor (stage IV),
 - Metastasis,
 - NAT,
 - Normal tissue
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Specification Sheet
| Pos |
No. |
Sex |
Age |
Organ |
Pathology diagnosis |
Grade |
Stage |
TNM |
Type † |
|
A1 |
1 |
M |
40 |
Gingiva |
Squamous cell carcinoma |
1 |
IV |
T4N0M0 |
Malignant |
|
A2 |
2 |
F |
47 |
Tongue |
Squamous cell carcinoma |
1 |
I |
T1N0M0 |
Malignant |
|
A3 |
3 |
M |
81 |
Lip |
Squamous cell carcinoma |
1 |
II |
T2N0M0 |
Malignant |
|
A4 |
4 |
M |
57 |
Tongue |
Squamous cell carcinoma |
1 |
I |
T1N0M0 |
Malignant |
|
A5 |
5 |
F |
52 |
Lip |
Squamous cell carcinoma |
2 |
I |
T1N0M0 |
Malignant |
|
A6 |
6 |
M |
53 |
Cheek |
Squamous cell carcinoma |
1 |
II |
T2N0M0 |
Malignant |
|
A7 |
7 |
F |
62 |
Cheek |
Squamous cell carcinoma |
1 |
I |
T1N0M0 |
Malignant |
|
A8 |
8 |
M |
48 |
Base of tongue |
Squamous cell carcinoma (salivary gland) |
– |
II |
T2N0M0 |
Malignant |
|
A9 |
9 |
M |
68 |
Right palate |
Squamous cell carcinoma |
1 |
II |
T2N0M0 |
Malignant |
|
A10 |
10 |
F |
56 |
Cheek |
Squamous cell carcinoma |
1 |
II |
T2N0M0 |
Malignant |
|
B1 |
11 |
M |
79 |
Cheek |
Squamous cell carcinoma |
1 |
II |
T2N0M0 |
Malignant |
|
B2 |
12 |
M |
60 |
Gingiva |
Squamous cell carcinoma |
1 |
I |
T1N0M0 |
Malignant |
|
B3 |
13 |
M |
55 |
Cheek |
Squamous cell carcinoma |
1 |
I |
T1N0M0 |
Malignant |
|
B4 |
14 |
M |
66 |
Tongue |
Squamous cell carcinoma |
1 |
I |
T1N0M0 |
Malignant |
|
B5 |
15 |
F |
46 |
Tongue |
Squamous cell carcinoma |
1 |
IV |
T1N0M1 |
Malignant |
|
B6 |
16 |
F |
39 |
Tongue |
Squamous cell carcinoma |
1 |
I |
T1N0M0 |
Malignant |
|
B7 |
17 |
M |
78 |
Tongue |
Squamous cell carcinoma |
1 |
II |
T2N0M0 |
Malignant |
|
B8 |
18 |
F |
78 |
Lip |
Squamous cell carcinoma |
1 |
IV |
T1N0M1 |
Malignant |
|
B9 |
19 |
F |
54 |
Lip |
Squamous cell carcinoma |
1 |
IV |
T1N0M1 |
Malignant |
|
B10 |
20 |
F |
75 |
Lip |
Squamous cell carcinoma |
1 |
IV |
T1N0M1 |
Malignant |
|
C1 |
21 |
M |
60 |
Tongue |
Squamous cell carcinoma |
1 |
I |
T1N0M0 |
Malignant |
|
C2 |
22 |
M |
73 |
Lip |
Squamous cell carcinoma |
1 |
I |
T1N0M0 |
Malignant |
|
C3 |
23 |
M |
60 |
Gingiva |
Squamous cell carcinoma |
2 |
I |
T1N0M0 |
Malignant |
|
C4 |
24 |
M |
78 |
Lip |
Squamous cell carcinoma |
2 |
I |
T1N0M0 |
Malignant |
|
C5 |
25 |
M |
55 |
Gingiva |
Squamous cell carcinoma |
2–3 |
I |
T1N0M0 |
Malignant |
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C6 |
26 |
M |
47 |
Lower mandible |
Squamous cell carcinoma |
3 |
II |
T2N0M0 |
Malignant |
|
C7 |
27 |
M |
41 |
Dental alveoli |
Squamous cell carcinoma |
3 |
I |
T1N0M0 |
Malignant |
|
C8 |
28 |
M |
60 |
Tongue |
Squamous cell carcinoma |
3 |
II |
T2N0M0 |
Malignant |
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C9 |
29 |
F |
40 |
Palate |
Adenoid cystic carcinoma |
– |
I |
T1N0M0 |
Malignant |
|
C10 |
30 |
M |
45 |
Left lower mandible |
Adenoid cystic carcinoma (sparse) |
– |
I |
T1N0M0 |
Malignant |
|
D1 |
31 |
M |
64 |
Palate |
Adenoid cystic carcinoma |
– |
II |
T2N0M0 |
Malignant |
|
D2 |
32 |
M |
66 |
Parotid gland |
Acinic cell carcinoma |
– |
II |
T2N0M0 |
Malignant |
|
D3 |
33 |
M |
71 |
Mouth floor |
Mucoepidermoid carcinoma |
1 |
I |
T1N0M0 |
Malignant |
|
D4 |
34 |
M |
57 |
Palate |
Mucoepidermoid carcinoma |
1 |
II |
T2N0M0 |
Malignant |
|
D5 |
35 |
F |
50 |
Cheek |
Mucoepidermoid carcinoma |
1 |
II |
T2N0M0 |
Malignant |
|
D6 |
36 |
M |
57 |
Upper lip |
Mucoepidermoid carcinoma (skeletal muscle and blood vessel) |
– |
I |
T1N0M0 |
Malignant |
|
D7 |
37 |
F |
48 |
Right lower mandible |
Mucoepidermoid carcinoma |
2 |
I |
T1N0M0 |
Malignant |
|
D8 |
38 |
M |
55 |
Gingiva |
Mucoepidermoid carcinoma |
3 |
I |
T1N0M0 |
Malignant |
|
D9 |
39 |
M |
60 |
Right lower mandible |
Mucoepidermoid carcinoma |
3 |
III |
T3N0M0 |
Malignant |
|
D10 |
40 |
M |
50 |
Root of tongue |
Mucoepidermoid carcinoma (sparse) |
– |
I |
T1N0M0 |
Malignant |
|
E1 |
41 |
F |
79 |
Lip |
Basal cell carcinoma (sparse) |
– |
II |
T2N0M0 |
Malignant |
|
E2 |
42 |
F |
48 |
Lip |
Basal cell carcinoma |
– |
II |
T2N0M0 |
Malignant |
|
E3 |
43 |
F |
70 |
Lymph node |
Metastatic squamous cell carcinoma of neck from cheek |
2 |
– |
– |
Metastasis |
|
E4 |
44 |
M |
79 |
Lymph node |
Metastatic squamous cell carcinoma of neck from tongue |
1 |
– |
– |
Metastasis |
|
E5 |
45 |
F |
59 |
Lymph node |
Metastatic squamous cell carcinoma of neck from mandible |
2 |
– |
– |
Metastasis |
|
E6 |
46 |
F |
40 |
Lymph node |
Metastatic mucoepidermoid carcinoma of neck from mandible |
3 |
– |
– |
Metastasis |
|
E7 |
47 |
M |
11 |
Mandible |
Adamantinoma |
– |
– |
– |
Benign |
|
E8 |
48 |
M |
28 |
Left mandible |
Adamantinoma |
– |
– |
– |
Benign |
|
E9 |
49 |
M |
51 |
Right mandible |
Adamantinoma |
– |
– |
– |
Benign |
|
E10 |
50 |
M |
64 |
Mandible |
Adamantinoma (fibrous tissue and blood vessel) |
– |
– |
– |
Benign |
|
F1 |
51 |
F |
37 |
Mandible |
Adamantinoma |
– |
– |
– |
Benign |
|
F2 |
52 |
M |
40 |
Lower mandible |
Adamantinoma |
– |
– |
– |
Benign |
|
F3 |
53 |
F |
47 |
Mandible |
Adamantinoma |
– |
– |
– |
Benign |
|
F4 |
54 |
F |
70 |
Right jaw bones |
Adamantinoma |
– |
– |
– |
Benign |
|
F5 |
55 |
M |
67 |
Lip |
Hyperplasia of squamous epithelium |
– |
– |
– |
Hyperplasia |
|
F6 |
56 |
M |
40 |
Lip |
Mild atypical hyperplasia of squamous epithelium |
– |
– |
– |
Hyperplasia |
|
F7 |
57 |
M |
82 |
Lip |
Hyperplasia of squamous epithelium |
– |
– |
– |
Hyperplasia |
|
F8 |
58 |
M |
46 |
Tongue |
Hyperplasia of squamous epithelium (skeletal muscle and blood vessel) |
– |
– |
– |
Hyperplasia |
|
F9 |
59 |
F |
60 |
Tongue |
Hyperplasia of squamous epithelium |
– |
– |
– |
Hyperplasia |
|
F10 |
60 |
F |
3 |
Tongue |
Hyperplasia of squamous epithelium |
– |
– |
– |
Hyperplasia |
|
G1 |
61 |
M |
68 |
Parotid gland |
Cancer adjacent tissue (with squamous cell carcioma sparse) |
– |
– |
– |
AT |
|
G2 |
62 |
F |
53 |
Tongue |
Cancer adjacent tissue |
– |
– |
– |
AT |
|
G3 |
63 |
M |
53 |
Tongue |
Cancer adjacent tissue (hyperplasia of squamous epithelium) |
– |
– |
– |
AT |
|
G4 |
64 |
M |
70 |
Parotid gland |
Cancer adjacent tissue (with mucoepidermoid carcinoma) |
2 |
– |
– |
AT |
|
G5 |
65 |
M |
63 |
Lip |
Cancer adjacent tissue (chronic inflammation of fibrous tissue and blood vessel) |
– |
– |
– |
AT |
|
G6 |
66 |
M |
43 |
Submaxillary gland |
Chronic submaxillaritis |
– |
– |
– |
Inflammation |
|
G7 |
67 |
F |
23 |
Parotid gland |
Chronic parotitis |
– |
– |
– |
Inflammation |
|
G8 |
68 |
F |
66 |
Parotid gland |
Chronic parotitis |
– |
– |
– |
Inflammation |
|
G9 |
69 |
F |
40 |
Right cheek |
Chronic inflammation of mucosa |
– |
– |
– |
Inflammation |
|
G10 |
70 |
F |
75 |
Lower lip |
Chronic inflammation of mucosa of No. 20 |
– |
– |
– |
Inflammation |
|
H1 |
71 |
F |
48 |
Salivary gland |
Cancer adjacent normal salivary gland tissue |
– |
– |
– |
NAT |
|
H2 |
72 |
F |
48 |
Salivary gland |
Cancer adjacent normal salivary gland tissue |
– |
– |
– |
NAT |
|
H3 |
73 |
M |
37 |
Salivary gland |
Cancer adjacent normal salivary gland tissue |
– |
– |
– |
NAT |
|
H4 |
74 |
M |
63 |
Salivary gland |
Cancer adjacent normal salivary gland tissue |
– |
– |
– |
NAT |
|
H5 |
75 |
M |
56 |
Salivary gland |
Cancer adjacent normal salivary gland tissue |
– |
– |
– |
NAT |
|
H6 |
76 |
F |
42 |
Tongue |
Normal tongue tissue |
– |
– |
– |
Normal |
|
H7 |
77 |
F |
38 |
Salivary gland |
Normal salivary gland tissue |
– |
– |
– |
Normal |
|
H8 |
78 |
M |
48 |
Tongue |
Normal tongue tissue |
– |
– |
– |
Normal |
|
H9 |
79 |
M |
50 |
Salivary gland |
Normal salivary gland tissue |
– |
– |
– |
Normal |
|
H10 |
80 |
M |
22 |
Salivary gland |
Normal salivary gland tissue |
– |
– |
– |
Normal |
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–
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– |
M |
58 |
Skin |
Malignant melanoma (tissue marker) |
– |
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Malignant |
† For precise diagnosis, refer to pathology description.
**The grade 1-3 (or I-III) in Pathology Diagnosis is equivalent to well-differentiated, moderately-differentiated or poorly differentiated, respectively, under microscope.
Grade 1 or well-differentiated: Cells appear normal and are not growing rapidly.
Grade 2 or moderately-differentiated: Cells appear slightly different than normal.
Grade 3 or poorly differentiated: Cells appear abnormal and tend to grow and spread more aggressively.
Grade 4 or undifferentiated: *(for certain tumors), features are not significantly distinguishing to make it look any different from undifferentiated cancers which occur in other organs.
TNM grading:
T - Primary tumor
Tx - Primary tumor cannot be assessed
T0 - No evidence of primary tumor
Tis - Carcinoma in situ; intraepithelial or invasion of lamina propria
T1 - Tumor invades submucosa
T2 - Tumor invades muscularis propria
T3 - Tumor invades through muscularis propria into subserosa or into non-peritonealized pericolic or perirectal tissues.
T4 - Tumor directly invades other organs or structures and/or perforate visceral peritoneum
N - Regional lymph nodes
Nx - Regional lymph nodes cannot be assessed
N0 - No regional lymph node metastasis
N1 - Metastasis in 1 to 3 regional lymph nodes
N2 - Metastasis in 4 or more regional lymph nodes
M - Distant metastasis
Mx - Distant metastasis cannot be assessed
M0 - No distant metastasis
M1 - Distant metastasis
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