Tissue Array
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US Biomax, Inc.
 

TMA2401

High density multiple organ (top 4) cancer tissue array (240 cores)
Unstained: $345.00 Add to Cart
Trial (TMA2401t*): $105.00 Add to Cart
H&E (TMA2401s*): $345.00 Add to Cart

Microarray Panel:Multiple organ carcinoma tissue microarray, containing 50 cases of cancer and 5 normal tissues of each organ (lung, prostate, breast, colon) , single core per case of cancer, duplicated cores per case of normal tissue
Cores:240
Cases:220
Layout:20 cols × 12 rows
Core Diameter:0.6 mm
Thickness:5 µm
Quality Control:Anti-Actin confirmed
Applications:Routine histology procedures including ImmunoHistochemistry (IHC) and In Situ Hybridization (ISH), protocols which can be found on our support page.
Notes:Unless specified, all TMA slides are not coated with extra layer of paraffin (tissue cores can be easily seen on the glass), so there is no need to bake, can be directly put into xylene for de-paraffin procedure.

*Tissue Microarray Slide Types:

  • Unstained: unstained paraffin tissue microarray slide.
  • Trial: tissue microarray trial slide. 10% - 25% of cores missing. Good for titrating antibody dilution and experiment conditions. Limited numbers are available, to 2 per item per order. Test slides (tissue arrays with catalog numbers ending with 241 or 242) are recommended as a substitute.
  • H & E: Hematoxylin and Eosin stained tissue microarray slide.

Specification Sheet

Pos No. Sex Age Organ Pathology diagnosis Grade Gleason Score TNM Type †
A1 1 M 49 Lung Squamous cell carcinoma 1 – T4N0M0 Malignant
A2 2 M 54 Lung Squamous cell carcinoma 1 – T2N3M0 Malignant
A3 3 M 51 Lung Squamous cell carcinoma 1 – T2N1M0 Malignant
A4 4 M 67 Lung Squamous cell carcinoma 1 – T2N1M0 Malignant
A5 5 M 63 Lung Squamous cell carcinoma 1 – T2N0M0 Malignant
A6 6 M 56 Lung Squamous cell carcinoma (tumoral necrosis) – – T2N0M0 Malignant
A7 7 M 71 Lung Squamous cell carcinoma 1 – T2N1M0 Malignant
A8 8 F 54 Lung Squamous cell carcinoma 1 – T3N3M0 Malignant
A9 9 M 60 Lung Squamous cell carcinoma 1 – – Malignant
A10 10 M 66 Lung Squamous cell carcinoma 1 – T2N1M0 Malignant
A11 11 M 67 Lung Squamous cell carcinoma 1 – T2N1M0 Malignant
A12 12 M 64 Lung Squamous cell carcinoma 1 – T2N1M0 Malignant
A13 13 M 61 Lung Squamous cell carcinoma 2 – T2N1M0 Malignant
A14 14 M 65 Lung Squamous cell carcinoma (bronchial tissue) – – T3N0M0 Malignant
A15 15 M 51 Lung Squamous cell carcinoma 1 – T2N3M0 Malignant
A16 16 M 62 Lung Squamous cell carcinoma 1 – T1N0M0 Malignant
A17 17 M 72 Lung Squamous cell carcinoma (pneumonic tissue) – – T2N1M0 Malignant
A18 18 F 69 Lung Squamous cell carcinoma 1 – T2N0M0 Malignant
A19 19 M 56 Lung Squamous cell carcinoma 2 – T2N1M0 Malignant
A20 20 M 37 Lung Squamous cell carcinoma (fibrous tissue) – – T2N1M0 Malignant
B1 21 M 56 Lung Squamous cell carcinoma 2 – T2N0M0 Malignant
B2 22 M 48 Lung Squamous cell carcinoma with necrosis 2 – T2N0M0 Malignant
B3 23 M 53 Lung Squamous cell carcinoma (sparse) with necrosis 2 – T3N0M0 Malignant
B4 24 F 40 Lung Squamous cell carcinoma 2 – T2N1M0 Malignant
B5 25 M 66 Lung Squamous cell carcinoma 2 – T2N1M0 Malignant
B6 26 M 61 Lung Squamous cell carcinoma 2 – T3N1M0 Malignant
B7 27 M 74 Lung Squamous cell carcinoma 2 – T2N1M0 Malignant
B8 28 M 63 Lung Squamous cell carcinoma 3 – T1N0M0 Malignant
B9 29 M 69 Lung Squamous cell carcinoma 2 – T3N3M0 Malignant
B10 30 F 54 Lung Squamous cell carcinoma 3 – T2N2M0 Malignant
B11 31 F 50 Lung Adenocarcinoma (fibrous tissue and lymphatic tissue) – – T2N1M0 Malignant
B12 32 M 34 Lung Adenocarcinoma 1 – T2N1M0 Malignant
B13 33 M 60 Lung Adenocarcinoma (sparse) 1 – T2N0M0 Malignant
B14 34 M 73 Lung Adenocarcinoma 1 – T2N0M0 Malignant
B15 35 F 64 Lung Mucinous adenocarcinoma 1 – T2N1M0 Malignant
B16 36 M 64 Lung Adenocarcinoma 1 – T2N3M0 Malignant
B17 37 M 81 Lung Adenocarcinoma 1 – T2N2M0 Malignant
B18 38 F 54 Lung Papillary adenocarcinoma 1 – T2N1M0 Malignant
B19 39 M 57 Lung Adenocarcinoma 1 – T2N0M0 Malignant
B20 40 M 53 Lung Adenocarcinoma 2 – T2N0M0 Malignant
C1 41 F 49 Lung Adenocarcinoma 2 – T1N0M0 Malignant
C2 42 F 52 Lung Adenocarcinoma 3 – T2N0M0 Malignant
C3 43 F 59 Lung Adenocarcinoma 3 – T2N1M0 Malignant
C4 44 M 60 Lung Adenocarcinoma 3 – TxN0M0 Malignant
C5 45 M 64 Lung Adenocarcinoma 2 – T1N0M0 Malignant
C6 46 F 60 Lung Adenocarcinoma 2 – T1N0M0 Malignant
C7 47 M 62 Lung Papillary adenocarcinoma 2 – T2N1M0 Malignant
C8 48 F 49 Lung Adenocarcinoma (bronchial tissue) – – T4N3M0 Malignant
C9 49 F 54 Lung Adenocarcinoma 3 – T3N0M0 Malignant
C10 50 F 70 Lung Bronchioloalveolar carcinoma – – T1N0M0 Malignant
C11 51 F 21 Lung Normal pneumonic tissue – – – Normal
C12 52 F 21 Lung Normal pneumonic tissue – – – Normal
C13 53 F 21 Lung Normal pneumonic tissue – – – Normal
C14 54 F 21 Lung Normal pneumonic tissue – – – Normal
C15 55 M 42 Lung Normal pneumonic tissue – – – Normal
C16 56 M 42 Lung Normal pneumonic tissue – – – Normal
C17 57 M 22 Lung Normal pneumonic tissue – – – Normal
C18 58 M 22 Lung Normal pneumonic tissue – – – Normal
C19 59 M 40 Lung Normal pneumonic tissue – – – Normal
C20 60 M 40 Lung Normal pneumonic tissue – – – Normal
D1 61 M 75 Prostate Adenocarcinoma 1 1+1 T2bNxM0 Malignant
D2 62 M 70 Prostate Adenocarcinoma 1 2+3 T2NxM0 Malignant
D3 63 M 61 Prostate Adenocarcinoma 1 2+2 T2NxM0 Malignant
D4 64 M 64 Prostate Adenocarcinoma 2 2+3 T2NxM0 Malignant
D5 65 M 66 Prostate Adenocarcinoma 2 2+2 T2NxM0 Malignant
D6 66 M 66 Prostate Adenocarcinoma 2 2+3 T2N1M0 Malignant
D7 67 M 75 Prostate Adenocarcinoma 1 2+2 T2NxM0 Malignant
D8 68 M 60 Prostate Adenocarcinoma 1 2+2 T2NxM0 Malignant
D9 69 M 54 Prostate Adenocarcinoma 1 2+1 T3NxM0 Malignant
D10 70 M 55 Prostate Adenocarcinoma 2 3+3 T2NxM0 Malignant
D11 71 M 78 Prostate Adenocarcinoma 3 3+5 T2NxM0 Malignant
D12 72 M 72 Prostate Adenocarcinoma 2 3+3 T4NxM0 Malignant
D13 73 M 65 Prostate Adenocarcinoma 1 2+2 T2NxM0 Malignant
D14 74 M 73 Prostate Adenocarcinoma 1 2+2 T2NxM0 Malignant
D15 75 M 73 Prostate Adenocarcinoma (prostatic tissue) – – T2NxM0 Malignant
D16 76 M 69 Prostate Adenocarcinoma 2 3+4 T2NxM0 Malignant
D17 77 M 20 Prostate Adenocarcinoma 2 3+3 T4NxM0 Malignant
D18 78 M 74 Prostate Adenocarcinoma 2 3+3 T2NxM0 Malignant
D19 79 M 82 Prostate Adenocarcinoma 2–3 3+5 T2NxM0 Malignant
D20 80 M 62 Prostate Adenocarcinoma (sparse) 2 3+3 T2NxM0 Malignant
E1 81 M 69 Prostate Adenocarcinoma 2 3+3 T2NxM0 Malignant
E2 82 M 69 Prostate Adenocarcinoma 2 3+3 T2NxM0 Malignant
E3 83 M 69 Prostate Adenocarcinoma (prostatic tissue) – – T3NxMo Malignant
E4 84 M 73 Prostate Adenocarcinoma 3 4+4 T2NxM0 Malignant
E5 85 M 51 Prostate Adenocarcinoma 2 3+2 T2NxM0 Malignant
E6 86 M 70 Prostate Adenocarcinoma (fibrous tissue and blood vessel) – – T2NxM0 Malignant
E7 87 M 58 Prostate Adenocarcinoma 2 3+3 T2NxM0 Malignant
E8 88 M 70 Prostate Adenocarcinoma (sparse) – – T3NxM0 Malignant
E9 89 M 69 Prostate Adenocarcinoma (smooth muscle) – – T1N0M0 Malignant
E10 90 M 65 Prostate Adenocarcinoma 3 4+3 T2NxM0 Malignant
E11 91 M 40 Prostate Adenocarcinoma 3 4+4 T2NxM0 Malignant
E12 92 M 73 Prostate Adenocarcinoma 3 4+4 T2NxM0 Malignant
E13 93 M 70 Prostate Adenocarcinoma 3 5+4 T2NxM0 Malignant
E14 94 M 73 Prostate Adenocarcinoma 3 5+4 T2NxM0 Malignant
E15 95 M 82 Prostate Adenocarcinoma (sparse) – – T2NxM0 Malignant
E16 96 M 56 Prostate Adenocarcinoma 3 3+3 T2NxM0 Malignant
E17 97 M 64 Prostate Adenocarcinoma 3 5+4 T2NxM0 Malignant
E18 98 M 60 Prostate Adenocarcinoma 2 2+3 T2NxM0 Malignant
E19 99 M 60 Prostate Adenocarcinoma (fibrous tissue and degenerative carcinoma tissue) – – T2NxM0 Malignant
E20 100 M 72 Prostate Adenocarcinoma 3 5+4 T2NxM0 Malignant
F1 101 M 75 Prostate Adenocarcinoma 4 5+5 T3NxM0 Malignant
F2 102 M 67 Prostate Adenocarcinoma 4 4+5 T2NxM0 Malignant
F3 103 M 82 Prostate Adenocarcinoma 3 4+4 T2NxM0 Malignant
F4 104 M 66 Prostate Adenocarcinoma (fibrous tissue) – – T2NxM0 Malignant
F5 105 M 87 Prostate Adenocarcinoma 4 5+5 T2NxM0 Malignant
F6 106 M 71 Prostate Adenocarcinoma 3 4+4 T2NxM0 Malignant
F7 107 M 72 Prostate Adenocarcinoma 3 4+4 T2NxM0 Malignant
F8 108 M 70 Prostate Adenocarcinoma (smooth muscle) – – T2NxM0 Malignant
F9 109 M 63 Prostate Adenocarcinoma 4 5+4 T2aNxM0 Malignant
F10 110 M 62 Prostate Adenocarcinoma with necrosis 3 5+4 T2NxM0 Malignant
F11 111 M 40 Prostate Normal prostatic tissue – – – Normal
F12 112 M 40 Prostate Normal prostatic tissue – – – Normal
F13 113 M 40 Prostate Normal prostatic tissue – – – Normal
F14 114 M 40 Prostate Normal prostatic tissue – – – Normal
F15 115 M 30 Prostate Normal prostatic tissue – – – Normal
F16 116 M 30 Prostate Normal prostatic tissue – – – Normal
F17 117 M 35 Prostate Normal prostatic tissue – – – Normal
F18 118 M 35 Prostate Normal prostatic tissue – – – Normal
F19 119 M 40 Prostate Normal prostatic tissue – – – Normal
F20 120 M 40 Prostate Normal prostatic tissue – – – Normal
G1 121 F 51 Breast Infiltrating ductal carcinoma 1 – T2N1M0 Malignant
G2 122 F 42 Breast Infiltrating ductal carcinoma 1 – T3N0M0 Malignant
G3 123 F 35 Breast Infiltrating ductal carcinoma 1 – T3N1M0 Malignant
G4 124 F 57 Breast Infiltrating ductal carcinoma (sparse) 1 – T2N0M0 Malignant
G5 125 F 36 Breast Infiltrating ductal carcinoma 1–2 – T2NxM0 Malignant
G6 126 F 45 Breast Infiltrating ductal carcinoma 1 – T2NxM0 Malignant
G7 127 F 47 Breast Infiltrating ductal carcinoma 1 – T2N1M0 Malignant
G8 128 F 71 Breast Infiltrating ductal carcinoma 1 – T2NxM0 Malignant
G9 129 F 40 Breast Infiltrating ductal carcinoma 1 – T2N1M0 Malignant
G10 130 F 52 Breast Infiltrating ductal carcinoma 1 – T3N1M0 Malignant
G11 131 F 35 Breast Infiltrating ductal carcinoma 2 – T2N1M0 Malignant
G12 132 F 50 Breast Infiltrating ductal carcinoma (fibrous tissue) – – T2N1M0 Malignant
G13 133 F 45 Breast Infiltrating ductal carcinoma (fibrous tissue) – – T4N1M0 Malignant
G14 134 F 39 Breast Infiltrating ductal carcinoma 2 – T2N1M0 Malignant
G15 135 F 45 Breast Infiltrating ductal carcinoma 2 – T3N1M0 Malignant
G16 136 F 66 Breast Infiltrating ductal carcinoma 2 – T2N1M0 Malignant
G17 137 F 53 Breast Infiltrating ductal carcinoma 2 – T2N0M0 Malignant
G18 138 F 33 Breast Infiltrating ductal carcinoma (fibrous tissue) – – T2N1M0 Malignant
G19 139 F 57 Breast Infiltrating ductal carcinoma 2 – T2N0M0 Malignant
G20 140 F 40 Breast Infiltrating ductal carcinoma 2 – T2N1M0 Malignant
H1 141 F 44 Breast Infiltrating ductal carcinoma 2 – T2N1M0 Malignant
H2 142 F 43 Breast Infiltrating ductal carcinoma 2 – T3NxM0 Malignant
H3 143 F 50 Breast Infiltrating ductal carcinoma (fibrous tissue) – – T2NxM0 Malignant
H4 144 F 52 Breast Infiltrating ductal carcinoma 2 – T3N1M0 Malignant
H5 145 F 39 Breast Infiltrating ductal carcinoma 2 – T2NxM0 Malignant
H6 146 F 52 Breast Infiltrating ductal carcinoma 2 – T3N1M0 Malignant
H7 147 F 32 Breast Infiltrating ductal carcinoma 2 – T2N1M0 Malignant
H8 148 F 52 Breast Infiltrating ductal carcinoma 2 – T4bN1M0 Malignant
H9 149 F 42 Breast Infiltrating ductal carcinoma 2 – T2N1M0 Malignant
H10 150 F 51 Breast Infiltrating ductal carcinoma 2 – T2N1M0 Malignant
H11 151 F 56 Breast Infiltrating ductal carcinoma 3 – T2N1M0 Malignant
H12 152 F 30 Breast Infiltrating ductal carcinoma 2 – T1N0M0 Malignant
H13 153 F 56 Breast Infiltrating ductal carcinoma 2 – T2N1M0 Malignant
H14 154 F 47 Breast Infiltrating ductal carcinoma 2 – T2N1M0 Malignant
H15 155 F 50 Breast Infiltrating ductal carcinoma 2 – T2N1M0 Malignant
H16 156 F 50 Breast Infiltrating ductal carcinoma 2 – T2N1M0 Malignant
H17 157 F 50 Breast Infiltrating ductal carcinoma 2–3 – T2N1M0 Malignant
H18 158 F 44 Breast Infiltrating ductal carcinoma (fibrofatty tissue) – – T2N1M0 Malignant
H19 159 F 32 Breast Infiltrating ductal carcinoma 2 – T2N1M0 Malignant
H20 160 F 48 Breast Infiltrating ductal carcinoma 2 – T2N1M0 Malignant
I1 161 F 87 Breast Infiltrating ductal carcinoma 2 – T2N1M0 Malignant
I2 162 F 65 Breast Infiltrating ductal carcinoma 2–3 – T2N0M0 Malignant
I3 163 F 54 Breast Infiltrating ductal carcinoma 3 – T3NxM0 Malignant
I4 164 F 45 Breast Infiltrating ductal carcinoma 3 – T4N2M0 Malignant
I5 165 F 37 Breast Infiltrating ductal carcinoma 3 – T2N1M0 Malignant
I6 166 F 66 Breast Infiltrating ductal carcinoma 3 – T2N1M0 Malignant
I7 167 F 68 Breast Infiltrating ductal carcinoma 3 – T2NxM0 Malignant
I8 168 F 51 Breast Infiltrating ductal carcinoma 3 – T1N1M0 Malignant
I9 169 F 44 Breast Infiltrating ductal carcinoma 3 – T3N0M0 Malignant
I10 170 F 55 Breast Infiltrating ductal carcinoma 3 – T4N1M0 Malignant
I11 171 F 27 Breast Normal breast tissue – – – Normal
I12 172 F 27 Breast Normal breast tissue – – – Normal
I13 173 F 21 Breast Normal breast tissue – – – Normal
I14 174 F 21 Breast Normal breast tissue (fibrofatty tissue) – – – Normal
I15 175 F 18 Breast Normal breast tissue – – – Normal
I16 176 F 18 Breast Normal breast tissue (fibrofatty tissue) – – – Normal
I17 177 F 15 Breast Normal breast tissue (fibrofatty tissue) – – – Normal
I18 178 F 15 Breast Normal breast tissue (fibrofatty tissue) – – – Normal
I19 179 F 21 Breast Normal breast tissue (fibrofatty tissue) – – – Normal
I20 180 F 21 Breast Normal breast tissue (fibrofatty tissue) – – – Normal
J1 181 M 67 Colon Adenocarcinoma 1 – T2N0M0 Malignant
– – M 58 Skin Malignant melanoma (tissue marker) – Malignant
J2 182 F 71 Colon Adenocarcinoma 1 – T3N0M0 Malignant
J3 183 M 63 Colon Adenocarcinoma 1 – T2N0M0 Malignant
J4 184 F 62 Colon Mucinous adenocarcinoma (sparse) 1 – TXNXM1 Malignant
J5 185 F 46 Colon Adenocarcinoma 1 – T3N0M0 Malignant
J6 186 F 82 Colon Adenocarcinoma 2 – T3N0M0 Malignant
J7 187 F 66 Colon Adenocarcinoma 2 – T3N0M0 Malignant
J8 188 M 56 Colon Adenocarcinoma 1 – T3N0M0 Malignant
J9 189 M 60 Colon Adenocarcinoma (fibrous tissue and smooth muscle) – – T3N1 Malignant
J10 190 F 70 Colon Adenocarcinoma 2 – T3N0M0 Malignant
J11 191 F 78 Colon Adenocarcinoma 2 – T3N1M0 Malignant
J12 192 M 62 Colon Adenocarcinoma 2 – T3N1M0 Malignant
J13 193 M 75 Colon Adenocarcinoma 2 – T3N0M0 Malignant
J14 194 M 71 Colon Adenocarcinoma 2 – T3N0M0 Malignant
J15 195 M 48 Colon Adenocarcinoma 2 – T3N1M0 Malignant
J16 196 F 50 Colon Adenocarcinoma 2 – T3N1M0 Malignant
J17 197 M 72 Colon Adenocarcinoma 2 – T4N0M0 Malignant
J18 198 F 51 Colon Adenocarcinoma 2 – T2N0M0 Malignant
J19 199 M 77 Colon Adenocarcinoma 2 – T4N0M0 Malignant
J20 200 M 78 Colon Adenocarcinoma 2 – T3N1M1 Malignant
K1 201 F 63 Colon Adenocarcinoma 2 – T3N1M0 Malignant
K2 202 M 68 Colon Adenocarcinoma 2 – T3N1M0 Malignant
K3 203 M 80 Colon Adenocarcinoma 2 – T4N2 Malignant
K4 204 M 67 Colon Adenocarcinoma 2 – T3N1M0 Malignant
K5 205 F 69 Colon Adenocarcinoma 2 – T3N1M0 Malignant
K6 206 M 75 Colon Adenocarcinoma 2 – T2N1M0 Malignant
K7 207 M 59 Colon Adenocarcinoma (necrotic tissue and mucage) – – T3N1M0 Malignant
K8 208 F 50 Colon Adenocarcinoma 2 – T3N1M0 Malignant
K9 209 F 54 Colon Adenocarcinoma 2 – T4N0M0 Malignant
K10 210 M 73 Colon Adenocarcinoma 2 – T3N0 Malignant
K11 211 F 76 Colon Adenocarcinoma 2 – T3N1M0 Malignant
K12 212 F 46 Colon Adenocarcinoma 2 – T3N1 Malignant
K13 213 F 41 Colon Adenocarcinoma 2 – T3N1M0 Malignant
K14 214 M 62 Colon Adenocarcinoma 2 – T2N0M0 Malignant
K15 215 M 52 Colon Adenocarcinoma 2 – T2N0M0 Malignant
K16 216 M 32 Colon Adenocarcinoma 2 – T3N0M0 Malignant
K17 217 F 68 Colon Adenocarcinoma (smooth muscle) – – T3N1M0 Malignant
K18 218 F 42 Colon Adenocarcinoma 2 – T2N0M0 Malignant
K19 219 M 75 Colon Adenocarcinoma (sparse) 2 – T3N0M0 Malignant
K20 220 F 72 Colon Papillary adenocarcinoma 2 – T3N0M0 Malignant
L1 221 F 67 Colon Adenocarcinoma 2 – T3N0M0 Malignant
L2 222 M 71 Colon Adenocarcinoma 2 – T2N0M0 Malignant
L3 223 F 66 Colon Adenocarcinoma 2 – T3N1M0 Malignant
L4 224 M 60 Colon Adenocarcinoma 3 – T3N1M0 Malignant
L5 225 F 73 Colon Adenocarcinoma 3 – T3N0M0 Malignant
L6 226 F 65 Colon Adenocarcinoma 2–3 – T3N1M0 Malignant
L7 227 M 76 Colon Adenocarcinoma with necrosis 3 – T3N0M0 Malignant
L8 228 F 54 Colon Mucinous adenocarcinoma (sparse) 3 – T4N4M4 Malignant
L9 229 M 70 Colon Adenocarcinoma 3 – T3N1M0 Malignant
L10 230 F 30 Colon Adenocarcinoma 3 – T3N1M0 Malignant
L11 231 M 40 Colon Normal colonic tissue – – – Normal
L12 232 M 40 Colon Normal colonic tissue – – – Normal
L13 233 M 40 Colon Normal colonic tissue – – – Normal
L14 234 M 40 Colon Normal colonic tissue – – – Normal
L15 235 M 35 Colon Normal colonic tissue – – – Normal
L16 236 M 35 Colon Normal colonic tissue – – – Normal
L17 237 M 35 Colon Normal colonic tissue – – – Normal
L18 238 M 35 Colon Normal colonic tissue (sparse) – – – Normal
L19 239 M 40 Colon Normal colonic tissue – – – Normal
L20 240 M 40 Colon Normal colonic tissue – – – Normal
– – M 58 Skin Malignant melanoma (tissue marker) – Malignant

† For precise diagnosis, refer to pathology description.

**The grade 1-3 (or I-III) in Pathology Diagnosis is equivalent to well-differentiated, moderately-differentiated or poorly differentiated, respectively, under microscope.
Grade 1 or well-differentiated: Cells appear normal and are not growing rapidly.
Grade 2 or moderately-differentiated: Cells appear slightly different than normal.
Grade 3 or poorly differentiated: Cells appear abnormal and tend to grow and spread more aggressively.
Grade 4 or undifferentiated: *(for certain tumors), features are not significantly distinguishing to make it look any different from undifferentiated cancers which occur in other organs.

TNM grading:

T - Primary tumor
Tx - Primary tumor cannot be assessed
T0 - No evidence of primary tumor
Tis - Carcinoma in situ; intraepithelial or invasion of lamina propria
T1 - Tumor invades submucosa
T2 - Tumor invades muscularis propria
T3 - Tumor invades through muscularis propria into subserosa or into non-peritonealized pericolic or perirectal tissues.
T4 - Tumor directly invades other organs or structures and/or perforate visceral peritoneum

N - Regional lymph nodes
Nx - Regional lymph nodes cannot be assessed
N0 - No regional lymph node metastasis
N1 - Metastasis in 1 to 3 regional lymph nodes
N2 - Metastasis in 4 or more regional lymph nodes

M - Distant metastasis
Mx - Distant metastasis cannot be assessed
M0 - No distant metastasis
M1 - Distant metastasis

Find overlapping cases with this tissue array:
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