US Biomax, Inc.

MNT241

Multiple tumor and normal tissue array for IHC antibody and ISH probe optimization and initial screening, 12 cases/24 cores

Microarray Panel:Multiple tumor and normal tissue microarray, seven different normal tissues (brain, breast, colon, liver, lung, prostate, tonsil) and five major tumor types in duplicates for IHC antibody and ISH probe optimization and initial screening. Majority of the tissues were from surgical resection. Those highlighted by '* were from autopsy
Cores:24
Cases:12
Layout:6 cols × 4 rows
Core Diameter:1.5 mm
Thickness:4 µm
Quality Control:H&E, IHC Vimentin/Cytokeratin
Applications:Routine histology procedures including ImmunoHistochemistry (IHC) and In Situ Hybridization (ISH), protocols which can be found on our support page.
Notes:Unless specified, all TMA slides are not coated with extra layer of paraffin (tissue cores can be easily seen on the glass), so there is no need to bake, can be directly put into xylene for de-paraffin procedure.


Microarray Panel Display

 
Slide Label: US Biomax, Inc. Tissue Array
123456
A Bra Bre Col Liv Lun Pro
B Bra Bre Col Liv Lun Pro
C Ton Bre Col Liv Lun Pro
D Ton Bre Col Liv Lun Pro
Legend: Bra - Brain*, Bre - Breast, Col - Colon, Liv - Liver, Lun - Lung, Pro - Prostate, Ton - Tonsil

- , - Malignant tumor, - Normal tissue

Specification Sheet

Pos No. Sex Age Organ Pathology diagnosis Grade TNM Image Type †
A1 1 M 46 Brain* Cerebral cortex Normal
A2 2 F 39 Breast Normal & hyperplasia Normal
A3 3 M 68 Colon Normal colon Normal
A4 4 M 52 Liver Normal & cell swelling Normal
A5 5 M 47 Lung Normal Normal
A6 6 M 74 Prostate Normal to hyperplasia Normal
B1 7 M 46 Brain* Cerebral cortex Normal
B2 8 F 39 Breast Normal & hyperplasia Normal
B3 9 M 68 Colon Normal colon Normal
B4 10 M 52 Liver Normal & cell swelling Normal
B5 11 M 47 Lung Normal Normal
B6 12 M 74 Prostate Normal to hyperplasia Normal
C1 13 M 25 Tonsil Reactive Inflammatory
C2 14 F 63 Breast Breast invasive ductual carcinoma II~III T2N2M0 Malignant
C3 15 M 51 Colon Colon carcinoma I~II T3N0M0 Malignant
C4 16 M 65 Liver Hepatocellular carcinoma III T2N0M0 Malignant
C5 17 M 55 Lung Lung squamous cell carcinoma III T2N0M0 Malignant
C6 18 M 47 Prostate Prostate adenocarcinoma III T2N0M0 Malignant
D1 19 M 25 Tonsil Reactive Inflammatory
D2 20 F 63 Breast Grade II~III II~III T2N2M0 Malignant
D3 21 M 51 Colon Grade I~II I~II T3N0M0 Malignant
D4 22 M 65 Liver Grade II~III III T2N0M0 Malignant
D5 23 M 55 Lung Grade II III T2N0M0 Malignant
D6 24 M 47 Prostate Grade II III T2N0M0 Malignant


† For precise diagnosis, refer to pathology description.

**The grade 1-3 (or I-III) in Pathology Diagnosis is equivalent to well-differentiated, moderately-differentiated or poorly differentiated, respectively, under microscope.
Grade 1 or well-differentiated: Cells appear normal and are not growing rapidly.
Grade 2 or moderately-differentiated: Cells appear slightly different than normal.
Grade 3 or poorly differentiated: Cells appear abnormal and tend to grow and spread more aggressively.
Grade 4 or undifferentiated: *(for certain tumors), features are not significantly distinguishing to make it look any different from undifferentiated cancers which occur in other organs.

TNM grading:

T - Primary tumor
Tx - Primary tumor cannot be assessed
T0 - No evidence of primary tumor
Tis - Carcinoma in situ; intraepithelial or invasion of lamina propria
T1 - Tumor invades submucosa
T2 - Tumor invades muscularis propria
T3 - Tumor invades through muscularis propria into subserosa or into non-peritonealized pericolic or perirectal tissues.
T4 - Tumor directly invades other organs or structures and/or perforate visceral peritoneum

N - Regional lymph nodes
Nx - Regional lymph nodes cannot be assessed
N0 - No regional lymph node metastasis
N1 - Metastasis in 1 to 3 regional lymph nodes
N2 - Metastasis in 4 or more regional lymph nodes

M - Distant metastasis
Mx - Distant metastasis cannot be assessed
M0 - No distant metastasis
M1 - Distant metastasis

Sorry, this tissue array cannot be compared to find overlapping cases.