US Biomax, Inc.

FDA808

FDA normal and tumor organ tissue array of human (2 slide set), replacing FDA807, 144 cases/144 cores, for FDA guidelines to test tissue specificity of antibodies, replaced by FDA808a

FDA808-1

Multiple organ normal tissue array, tissue 72 cores, replaced by FDA808a-1

Microarray Panel:Multiple organ normal tissue microarray, 24 common types of normal human organs, including cerebrum, cerebellum, adrenal gland, ovary, pancreas, parathyroid gland, hypophysis, testis, thyroid gland, breast, spleen, tonsil, thymus, bone marrow, lung, cardiac muscle, esophagus, stomach, small intestine, colon, liver, salivary gland, kidney and prostate, each type taken from 3 normal human individuals, single core per case
Cores:72
Cases:72
Layout:9 cols × 8 rows
Core Diameter:1.5 mm
Thickness:5 µm
Quality Control:Anti-Actin confirmed
Applications:Routine histology procedures including ImmunoHistochemistry (IHC) and In Situ Hybridization (ISH), protocols which can be found on our support page.
Notes:Unless specified, all TMA slides are not coated with extra layer of paraffin (tissue cores can be easily seen on the glass), so there is no need to bake, can be directly put into xylene for de-paraffin procedure.


Microarray Panel Display

 
Slide Label: US Biomax, Inc. Tissue Array
123456789 
A Cer Cer Cer Cer Cer Cer Adr Adr Adr  
B Ova Ova Ova Pan Pan Pan Par Par Par  
C Hyp Hyp Hyp Tes Tes Tes Thy Thy Thy  
D Bre Bre Bre Spl Spl Spl Ton Ton Ton  
E Thy Thy Thy Bon Bon Bon Lun Lun Lun  
F Hea Hea Hea Eso Eso Eso Sto Sto Sto  
G Sma Sma Sma Col Col Col Liv Liv Liv  
H Sal Sal Sal Kid Kid Kid Pro Pro Pro Marked point
Legend: Adr - Adrenal gland, Bon - Bone marrow, Bre - Breast, Cer - Cerebellum, Col - Colon, Eso - Esophagus, Hea - Heart, Hyp - Hypophysis, Kid - Kidney, Liv - Liver, Lun - Lung, Ova - Ovary, Pan - Pancreas, Par - Parathyroid gland, Pro - Prostate, Sal - Salivary gland, Sma - Small intestine, Spl - Spleen, Sto - Stomach, Tes - Testis, Thy - Thymus gland, Ton - Tonsil

- Malignant tumor, - Normal tissue

Specification Sheet

Pos No. Sex Age Organ Pathology diagnosis Type †
A1 1 F 2 Cerebrum Normal cerebrum tissue Normal
A2 2 F 50 Cerebrum Normal cerebrum tissue Normal
A3 3 F 42 Cerebrum Normal cerebrum tissue Normal
A4 4 F 24 Cerebellum Normal cerebellum tissue Normal
A5 5 F 58 Cerebellum Normal cerebellum tissue Normal
A6 6 F 8 Cerebellum Normal cerebellum tissue Normal
A7 7 F 14 Adrenal gland Normal adrenal gland tissue Normal
A8 8 M 1 Mon. Adrenal gland Normal adrenal gland tissue Normal
A9 9 F 21 Adrenal gland Normal adrenal gland tissue Normal
B1 10 F 41 Ovary Normal ovary tissue Normal
B2 11 F 49 Ovary Normal ovary tissue Normal
B3 12 F 49 Ovary Normal ovary tissue Normal
B4 13 F 35 Pancreas Normal pancreas tissue Normal
B5 14 F 21 Pancreas Normal pancreas tissue Normal
B6 15 M 35 Pancreas Normal pancreas tissue Normal
B7 16 F 50 Parathyroid gland Normal thyroid gland tissue Normal
B8 17 F 40 Parathyroid gland Normal thyroid gland tissue Normal
B9 18 M 50 Parathyroid gland Normal parathyroid gland tissue Normal
C1 19 F 40 Hypophysis Normal hypophysis tissue Normal
C2 20 M 17 Hypophysis Normal hypophysis tissue Normal
C3 21 F 15 Hypophysis Normal hypophysis tissue Normal
C4 22 M 30 Testis Normal testis tissue Normal
C5 23 M 74 Testis Normal testis tissue Normal
C6 24 M 65 Testis Normal testis tissue Normal
C7 25 M 37 Thyroid gland Normal thyroid gland tissue Normal
C8 26 M 22 Thyroid gland Normal thyroid gland tissue Normal
C9 27 M 50 Thyroid gland Normal thyroid gland tissue Normal
D1 28 F 35 Breast Normal breast tissue Normal
D2 29 F 33 Breast Normal breast tissue Normal
D3 30 F 40 Breast Normal breast tissue Normal
D4 31 F 2 Spleen Normal spleen tissue Normal
D5 32 M 35 Spleen Normal spleen tissue Normal
D6 33 M 30 Spleen Normal spleen tissue Normal
D7 34 F 15 Tonsil Normal tonsil tissue Normal
D8 35 F 18 Tonsil Normal tonsil tissue Normal
D9 36 M 50 Tonsil Normal tonsil tissue Normal
E1 37 M 7 Mon. Thymus gland Normal thymus gland tissue Normal
E2 38 F 15 Thymus gland Normal thymus gland tissue Normal
E3 39 M 16 Thymus gland Normal thymus gland tissue Normal
E4 40 M 56 Bone marrow Normal myeloid tissue Normal
E5 41 F 61 Bone marrow Normal myeloid tissue Normal
E6 42 M 70 Bone marrow Normal myeloid tissue Normal
E7 43 M 24 Lung Normal lung tissue Normal
E8 44 M 42 Lung Normal lung tissue Normal
E9 45 M 48 Lung Normal lung tissue Normal
F1 46 M 56 Heart Normal cardiac muscle tissue Normal
F2 47 F 42 Heart Normal cardiac muscle tissue Normal
F3 48 F 35 Heart Normal cardiac muscle tissue Normal
F4 49 M 35 Esophagus Normal esophagus tissue Normal
F5 50 M 24 Esophagus Normal esophagus tissue Normal
F6 51 F 42 Esophagus Normal esophagus tissue Normal
F7 52 M 48 Stomach Normal stomach tissue Normal
F8 53 M 35 Stomach Normal stomach tissue Normal
F9 54 M 56 Stomach Normal stomach tissue (smooth muscle tissue) Normal
G1 55 M 40 Small intestine Normal small intestine tissue Normal
G2 56 M 25 Small intestine Normal small intestine tissue (smooth muscle tissue) Normal
G3 57 M 35 Small intestine Normal small intestine tissue Normal
G4 58 M 62 Colon Normal colon tissue Normal
G5 59 M 30 Colon Normal colon tissue Normal
G6 60 M 35 Colon Normal colon tissue (smooth muscle tissue) Normal
G7 61 M 40 Liver Normal liver tissue Normal
G8 62 F 35 Liver Normal liver tissue Normal
G9 63 M 35 Liver Normal liver tissue Normal
H1 64 M 50 Salivary gland Normal salivary gland tissue Normal
H2 65 M 77 Salivary gland Normal salivary gland tissue Normal
H3 66 F 34 Salivary gland Normal salivary gland tissue Normal
H4 67 F 14 Kidney Normal kidney tissue Normal
H5 68 M 48 Kidney Normal kidney tissue Normal
H6 69 F 50 Kidney Normal kidney tissue Normal
H7 70 M 27 Prostate Normal prostate tissue Normal
H8 71 M 43 Prostate Normal prostate tissue Normal
H9 72 M 28 Prostate Normal prostate tissue Normal
M 58 Skin Malignant melanoma (tissue marker) Malignant

† For precise diagnosis, refer to pathology description.


Find overlapping cases with this tissue array:

FDA808-2

Multiple normal organ and tumor tissue array with adjacent normal human organs, including TNM and pathology grade, 72 cases/72 cores, replaced by FDA808a-2

Microarray Panel:Multiple normal organ and tumor tissue microarray with normal and (cancer) adjacent normal human organs, containing 54 cases of tumor of varieties of organ tissue, plus 18 cases of 6 types of adjacent normal organs, single core per case
Cores:72
Cases:72
Layout:9 cols × 8 rows
Core Diameter:1.5 mm
Thickness:5 µm
Quality Control:Anti-Actin confirmed
Applications:Routine histology procedures including ImmunoHistochemistry (IHC) and In Situ Hybridization (ISH), protocols which can be found on our support page.
Notes:Unless specified, all TMA slides are not coated with extra layer of paraffin (tissue cores can be easily seen on the glass), so there is no need to bake, can be directly put into xylene for de-paraffin procedure.


Microarray Panel Display

 
Slide Label: US Biomax, Inc. Tissue Array
123456789 
A Ute Ute Ute Ute Ute Ute Ske Ske Thr  
B Ski Ski Ski Ner Ner Ner Lun Lun Lun  
C Cer Cer Cer Cer Ova Ova Pan Pan Tes  
D Tes Thr Thr Bre Bre Bre Spl Lun Lun  
E Lun Eso Eso Sto Sma Sma Col Abd Rec  
F Rec Liv Liv Kid Pro Pro Ute Ute Ute  
G Ute Ute Str Rec Ski Ski Sof Ret Abd  
H Med Lym Lym Pel Bla Bla Bon Ret Smo Marked point
Legend: Abd - Abdominal cavity, Bla - Bladder, Bon - Bone, Bre - Breast, Cer - Cerebrum, Col - Colon, Eso - Esophagus, Kid - Kidney, Liv - Liver, Lun - Lung, Lym - Lymph node, Med - Mediastinum, Ner - Nerve, Ova - Ovary, Pan - Pancreas, Pel - Pelvic cavity, Pro - Prostate, Rec - Rectum, Ret - Retroperitoneum, Ske - Skeletal muscle, Ski - Skin, Sma - Small intestine, Smo - Smooth muscle, Sof - Soft tissue, Spl - Spleen, Sto - Stomach, Str - Striated muscle, Tes - Testis, Thr - Thyroid, Ute - Uterine cervix

- Benign tumor, - Benign tumor, - Malignant tumor, - Malignant tumor, - Malignant tumor (stage 0), - Malignant tumor (stage I), - Malignant tumor (stage II), - Malignant tumor (stage III), - Malignant tumor (stage IIIb), - Malignant tumor (stage IIa), - Malignant tumor (stage IIb), - Malignant tumor (stage Ia), - Malignant tumor (stage Ib), - NAT, - Normal tissue

Specification Sheet

Pos No. Sex Age Organ Pathology diagnosis Grade Stage TNM Type †
A1 1 F 21 Uterus No normal endometrium tissue (smooth muscle and blood vessel) Normal
A2 2 F 21 Uterus Normal endometrium tissue Normal
A3 3 F 18 Uterus Normal endometrium tissue Normal
A4 4 F 32 Uterine cervix Cancer adjacent normal cervical canals tissue NAT
A5 5 F 18 Uterine cervix Normal cervical canals tissue Normal
A6 6 F 35 Uterus Cancer adjacent normal cervix tissue NAT
A7 7 M 38 Skeletal muscle Normal skeletal muscle tissue Normal
A8 8 F 40 Skeletal muscle Normal skeletal muscle tissue Normal
A9 9 M 48 Thyroid Normal thyroid gland tissue (with hyperplasia in follicles) Normal
B1 10 F 42 Skin Normal skin tissue Normal
B2 11 M 47 Skin Normal skin tissue Normal
B3 12 F 18 Skin Normal skin tissue Normal
B4 13 F 15 Nerve Normal peripheral nerve tissue Normal
B5 14 F 18 Nerve Normal peripheral nerve tissue Normal
B6 15 M 47 Nerve Normal peripheral nerve tissue Normal
B7 16 M 48 Lung Normal lung tissue (pneumonia) Normal
B8 17 M 22 Lung Normal lung tissue (some alveoli not intact) Normal
B9 18 M 24 Lung Normal lung tissue Normal
C1 19 F 61 Cerebrum Glioblastoma Malignant
C2 20 F 65 Cerebrum Atypical meningioma Malignant
C3 21 F 15 Cerebrum Malignant ependymoma Malignant
C4 22 M 55 Cerebrum Malignant oligodendroglioma Malignant
C5 23 F 63 Ovary Serous adenocarcinoma 3 II T2N0M0 Malignant
C6 24 F 29 Ovary Adenocarcinoma (sparse) 3 III T3N0M0 Malignant
C7 25 F 12 Pancreas Islet cell carcinoma Malignant
C8 26 M 64 Pancreas Adenocarcinoma 3 II T2N0M0 Malignant
C9 27 M 32 Testis Seminoma I T1N0M0 Malignant
D1 28 M 30 Testis Embryonal carcinoma I T2N0M0 Malignant
D2 29 F 33 Thyroid Medullary carcinoma II T3N0M0 Malignant
D3 30 F 36 Thyroid Papillary carcinoma III T2aN1M0 Malignant
D4 31 F 48 Breast Intraductal carcinoma with early infiltrate 0 TisN0M0 Malignant
D5 32 F 43 Breast Invasive ductal carcinoma 2 IIa T2N0M0 Malignant
D6 33 F 58 Breast Invasive ductal carcinoma 2 IIb T2N1M0 Malignant
D7 34 M 21 Spleen Diffuse B-cell lymphoma Malignant
D8 35 M 61 Lung Small cell undifferentiated carcinoma I T2N0M0 Malignant
D9 36 M 66 Lung Squamous cell carcinoma 3 I T2N0M0 Malignant
E1 37 F 75 Lung Adenocarcinoma 2 II T2N1M0 Malignant
E2 38 M 60 Esophagus Squamous cell carcinoma 2 IIa T2N0M0 Malignant
E3 39 M 63 Esophagus Adenocarcinoma 3 IIa T3N0M0 Malignant
E4 40 F 73 Stomach Mucinous adenocarcinoma 3 II T2N1M0 Malignant
E5 41 M 50 Small intestine Adenocarcinoma 2 II T3N0M0 Malignant
E6 42 F 71 Small intestine Malignant interstitialoma IIb T2N0M0 Malignant
E7 43 F 72 Colon Adenocarcinoma 2 II T4N0M0 Malignant
E8 44 M 54 Abdominal cavity Interstitialoma IIb T2N0M0 Malignant
E9 45 M 36 Rectum Adenocarcinoma 2 I T2N0M0 Malignant
F1 46 F 63 Rectum Intermediate grade malignant interstitialoma IIb T2N0M0G2 Malignant
F2 47 F 55 Liver Hepatocellular carcinoma 1 III T3N0M0 Malignant
F3 48 F 17 Liver Hepatoblastoma Malignant
F4 49 M 54 Kidney Clear cell carcinoma 2 I T1N0M0 Malignant
F5 50 M 67 Prostate Adenocarcinoma (Gleason grade:5 Gleason score:4+5) 3 II T2N0M0 Malignant
F6 51 M 77 Prostate Adenocarcinoma (Gleason grade:2 Gleason score:3+4) 2 II T2N0M0G4 Malignant
F7 52 F 33 Uterus Leiomyoma IIa T1bN0M0 Benign
F8 53 F 55 Uterus Adenocarcinoma endometrium 3 IIa T2aN0M0 Malignant
F9 54 F 39 Uterus Clear cell carcinoma with necrosis IIb T2bN0M0 Malignant
G1 55 F 36 Uterine cervix Squamous cell carcinoma 3 IIIb T1bN1M0 Malignant
G2 56 F 49 Uterine cervix Squamous cell carcinoma 3 II T2N0M0 Malignant
G3 57 F 20 Striated muscle Embryonal rhabdomyosarcom of left leg Ia T1aN0M0 Malignant
G4 58 F 70 Rectum Malignant melanoma (necrotic tissue) II T4N0M0 Malignant
G5 59 M 57 Skin Basal cell carcinoma of head I T2N0M0 Malignant
G6 60 M 46 Skin Squamous cell carcinoma of left chest wall 2 II T3N0M0 Malignant
G7 61 M 59 Soft tissue Neurofibroma Benign
G8 62 F 3 Retroperitoneum Neuroblastoma IIIb T2bN0M0 Malignant
G9 63 M 60 Abdominal cavity Malignant mesothelioma I T2N0M0 Malignant
H1 64 M 49 Mediastinum Diffuse B-cell lymphoma Malignant
H2 65 F 50 Lymph node Diffuse B cell lymphoma of right thigh Malignant
H3 66 M 53 Lymph node Hodgkin's lymphoma Malignant
H4 67 F 19 Pelvic cavity Large cell anaplastic lymphoma Malignant
H5 68 M 76 Bladder Transitional cell carcinoma 3 II T3aN0M0 Malignant
H6 69 M 62 Bladder Low grade malignant leiomyosarcoma Ib T2bN0M0G1 Malignant
H7 70 F 7 Bone Osteosarcoma of right inferior extremity femur IIIb T2N0M0 Malignant
H8 71 F 48 Retroperitoneum Spindle cell rhabdomyosarcoma IIb T2N0M0G2 Malignant
H9 72 F 60 Smooth muscle Intermediate grade malignant leiomyosarcoma of left buttock IIIb T2bN0M0 Malignant
F 55 liver Hepatocellular liver cancer (tissue marker) 3 T3N0M0 Malignant

† For precise diagnosis, refer to pathology description.

**The grade 1-3 (or I-III) in Pathology Diagnosis is equivalent to well-differentiated, moderately-differentiated or poorly differentiated, respectively, under microscope.
Grade 1 or well-differentiated: Cells appear normal and are not growing rapidly.
Grade 2 or moderately-differentiated: Cells appear slightly different than normal.
Grade 3 or poorly differentiated: Cells appear abnormal and tend to grow and spread more aggressively.
Grade 4 or undifferentiated: *(for certain tumors), features are not significantly distinguishing to make it look any different from undifferentiated cancers which occur in other organs.

TNM grading:

T - Primary tumor
Tx - Primary tumor cannot be assessed
T0 - No evidence of primary tumor
Tis - Carcinoma in situ; intraepithelial or invasion of lamina propria
T1 - Tumor invades submucosa
T2 - Tumor invades muscularis propria
T3 - Tumor invades through muscularis propria into subserosa or into non-peritonealized pericolic or perirectal tissues.
T4 - Tumor directly invades other organs or structures and/or perforate visceral peritoneum

N - Regional lymph nodes
Nx - Regional lymph nodes cannot be assessed
N0 - No regional lymph node metastasis
N1 - Metastasis in 1 to 3 regional lymph nodes
N2 - Metastasis in 4 or more regional lymph nodes

M - Distant metastasis
Mx - Distant metastasis cannot be assessed
M0 - No distant metastasis
M1 - Distant metastasis

Find overlapping cases with this tissue array: