|
|
|
|
FDA807-2
Multiple organ tumor tissue array with adjacent normal human organs, including TNM and pathology grade, 72 cases/72 cores, replacing FDA806-2
|
|
| Microarray Panel: | Multiple organ tumor tissue microarray with adjacent normal human organs, containing 54 cases of tumor of varieties of organ tissue, plus 18 cases of 6 types of adjacent normal organs, single core per case |
| Cores: | 72 |
|
| Cases: | 72 |
| Layout: | 9 cols × 8 rows |
| Core Diameter: | 1.5 mm |
| Thickness: | 5 µm | | Quality Control: | Anti-Actin confirmed | | Applications: | Routine histology procedures including ImmunoHistochemistry (IHC) and In Situ Hybridization (ISH), protocols which can be found on our support page. |
| Notes: | Unless specified, all TMA slides are not coated with extra layer of paraffin (tissue cores can be easily seen on the glass), so there is no need to bake, can be directly put into xylene for de-paraffin procedure. |
*Tissue Microarray Slide Types:
- Unstained: unstained
paraffin
tissue microarray slide.
- Trial: tissue microarray trial slide. 10% - 25% of cores missing. Good for titrating antibody dilution and experiment conditions. Limited numbers are available, to 2 per item per order. Test slides (tissue arrays with catalog numbers ending with 241 or 242) are recommended as a substitute.
- H & E: Hematoxylin and Eosin stained tissue microarray slide.
Microarray Panel Display  | | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | |
| A |
|
|
|
|
|
|
|
|
|
|
| B |
|
|
|
|
|
|
|
|
|
|
| C |
|
|
|
|
|
|
|
|
|
|
| D |
|
|
|
|
|
|
|
|
|
|
| E |
|
|
|
|
|
|
|
|
|
|
| F |
|
|
|
|
|
|
|
|
|
|
| G |
|
|
|
|
|
|
|
|
|
|
| H |
|
|
|
|
|
|
|
|
|
 |
|
| Legend: | Abd - Abdominal cavity,
Bla - Bladder,
Bon - Bone,
Bre - Breast,
Cer - Cerebrum,
Col - Colon,
Eso - Esophagus,
Int - Intestine,
Kid - Kidney,
Liv - Liver,
Lun - Lung,
Lym - Lymph node,
Ner - Nerve,
Ova - Ovary,
Pan - Pancreas,
Pro - Prostate,
Rec - Rectum,
Ret - Retroperitoneum,
Ski - Skin,
Smo - Smooth muscle,
Sof - Soft tissue,
Spl - Spleen,
Sto - Stomach,
Str - Striated muscle,
Tes - Testis,
Thr - Thyroid,
Thy - Thyroid gland,
Ute - Uterine cervix
- Benign tumor,
- Malignant tumor,
- Malignant tumor,
- Malignant tumor (stage I),
- Malignant tumor (stage II),
- Malignant tumor (stage III),
- Malignant tumor (stage IIIb),
- Malignant tumor (stage IIa),
- Malignant tumor (stage IIb),
- Malignant tumor (stage IV),
- Malignant tumor (stage Ia),
- Malignant tumor (stage Ib),
- Malignant tumor (stage Ic),
- NAT,
- Normal tissue
|
Specification Sheet
| Pos |
No. |
Sex |
Age |
Organ |
Pathology diagnosis |
Grade |
Stage |
TNM |
Type † |
|
A1 |
1 |
F |
21 |
Uterus |
Normal endometrium tissue |
– |
– |
– |
Normal |
|
A2 |
2 |
F |
21 |
Uterus |
Normal endometrium tissue |
– |
– |
– |
Normal |
|
A3 |
3 |
F |
18 |
Uterus |
Normal endometrium tissue |
– |
– |
– |
Normal |
|
A4 |
4 |
F |
30 |
Uterus |
Cancer adjacent normal cervix tissue |
– |
– |
– |
NAT |
|
A5 |
5 |
F |
50 |
Uterus |
Cancer adjacent normal cervix tissue |
– |
– |
– |
NAT |
|
A6 |
6 |
F |
31 |
Uterus |
Cancer adjacent normal cervix tissue with focal hyperplasia of squamous epithelium |
– |
– |
– |
NAT |
|
A7 |
7 |
F |
21 |
Striated muscle |
Normal skeletal muscle tissue |
– |
– |
– |
Normal |
|
A8 |
8 |
M |
30 |
Striated muscle |
Normal skeletal muscle tissue |
– |
– |
– |
Normal |
|
A9 |
9 |
M |
35 |
Striated muscle |
Normal skeletal muscle tissue |
– |
– |
– |
Normal |
|
B1 |
10 |
F |
18 |
Skin |
Normal skin tissue |
– |
– |
– |
Normal |
|
B2 |
11 |
M |
37 |
Skin |
Normal skin tissue |
– |
– |
– |
Normal |
|
B3 |
12 |
M |
34 |
Skin |
Normal skin tissue |
– |
– |
– |
Normal |
|
B4 |
13 |
F |
15 |
Nerve |
Normal nervous tissue (sparse) |
– |
– |
– |
Normal |
|
B5 |
14 |
F |
27 |
Nerve |
Normal nervous tissue |
– |
– |
– |
Normal |
|
B6 |
15 |
M |
31 |
Nerve |
Normal nervous tissue |
– |
– |
– |
Normal |
|
B7 |
16 |
M |
48 |
Lung |
Normal mesothelium tissue (lung tissue sparse) |
– |
– |
– |
Normal |
|
B8 |
17 |
M |
22 |
Lung |
Normal mesothelium and lung tissue |
– |
– |
– |
Normal |
|
B9 |
18 |
M |
47 |
Lung |
Normal mesothelium tissue (lung tissue) |
– |
– |
– |
Normal |
|
C1 |
19 |
F |
59 |
Cerebrum |
Glioblastoma |
– |
– |
– |
Malignant |
|
C2 |
20 |
F |
65 |
Cerebrum |
Atypical meningioma |
– |
– |
– |
Malignant |
|
C3 |
21 |
F |
15 |
Cerebrum |
Malignant ependymoma |
– |
– |
– |
Malignant |
|
C4 |
22 |
M |
55 |
Cerebrum |
Malignant oligodendroglioma |
– |
– |
– |
Malignant |
|
C5 |
23 |
F |
49 |
Ovary |
Serous papillary adenocarcinoma |
3 |
II |
T3N0M0 |
Malignant |
|
C6 |
24 |
F |
54 |
Ovary |
Mucinous papillary adenocarcinoma |
2 |
IIa |
T2aN0M0 |
Malignant |
|
C7 |
25 |
M |
25 |
Pancreas |
Islet cell carcinoma |
– |
II |
T2N0M0 |
Malignant |
|
C8 |
26 |
M |
64 |
Pancreas |
Adenocarcinoma |
3 |
II |
T3N0M0 |
Malignant |
|
C9 |
27 |
M |
32 |
Testis |
Seminoma |
– |
– |
– |
Malignant |
|
D1 |
28 |
M |
25 |
Testis |
Embryonal carcinoma |
– |
II |
T4N1M0 |
Malignant |
|
D2 |
29 |
F |
33 |
Thyroid |
Medullary carcinoma |
– |
II |
T3N0M0 |
Malignant |
|
D3 |
30 |
F |
36 |
Thyroid gland |
Papillary carcinoma |
– |
III |
T2aN1M0 |
Malignant |
|
D4 |
31 |
F |
28 |
Breast |
Intraductal carcinoma |
– |
IIb |
T3N0M0 |
Malignant |
|
D5 |
32 |
F |
43 |
Breast |
Intraductal carcinoma with early infiltrate |
– |
IIa |
T2N0M0 |
Malignant |
|
D6 |
33 |
F |
39 |
Breast |
Invasive ductal carcinoma |
2 |
IIb |
T2N1M0 |
Malignant |
|
D7 |
34 |
M |
27 |
Spleen |
Diffuse large B-cell lymphoma |
– |
– |
– |
Malignant |
|
D8 |
35 |
M |
44 |
Lung |
Small cell undifferentiated carcinoma |
– |
II |
T2N1M0 |
Malignant |
|
D9 |
36 |
M |
67 |
Lung |
Squamous cell carcinoma |
2 |
II |
T2N1M0 |
Malignant |
|
E1 |
37 |
F |
64 |
Lung |
Adenocarcinoma |
2 |
I |
T2N0M0 |
Malignant |
|
E2 |
38 |
F |
57 |
Esophagus |
Squamous cell carcinoma |
2 |
IIa |
T2N0M0 |
Malignant |
|
E3 |
39 |
F |
67 |
Esophagus |
Adenocarcinoma |
3 |
III |
T4N0M0 |
Malignant |
|
E4 |
40 |
F |
73 |
Stomach |
Mucinous adenocarcinoma |
3 |
II |
T2N1M0 |
Malignant |
|
E5 |
41 |
M |
50 |
Colon |
Adenocarcinoma |
2 |
II |
T3N0M0 |
Malignant |
|
E6 |
42 |
F |
71 |
Intestine |
Intermediate grade malignant interstitialoma |
– |
IIb |
T2bN0M0 |
Malignant |
|
E7 |
43 |
M |
74 |
Colon |
Adenocarcinoma |
2 |
II |
T3N0M0 |
Malignant |
|
E8 |
44 |
M |
54 |
Abdominal cavity |
Malignant interstitialoma |
– |
IIb |
T2N0M0 |
Malignant |
|
E9 |
45 |
F |
50 |
Rectum |
Adenocarcinoma |
2 |
II |
T3N1M0 |
Malignant |
|
F1 |
46 |
M |
32 |
Rectum |
Interstitialoma |
– |
IIa |
T1bN0M0 |
Malignant |
|
F2 |
47 |
M |
61 |
Liver |
Hepatocellular carcinoma |
2 |
II |
T2N0M0 |
Malignant |
|
F3 |
48 |
F |
17 |
Liver |
Hepatoblastoma |
– |
– |
– |
Malignant |
|
F4 |
49 |
M |
58 |
Kidney |
Clear cell carcinoma |
1 |
II |
T2N0M0 |
Malignant |
|
F5 |
50 |
M |
76 |
Prostate |
Adenocarcinoma (carcinoma sparse) |
– |
IV |
T3N1M1b |
Malignant |
|
F6 |
51 |
M |
72 |
Prostate |
Adenocarcinoma (Gleason grade:4 Gleason score:4+5) |
4 |
IV |
T2N0M1 |
Malignant |
|
F7 |
52 |
F |
45 |
Uterus |
Leiomyoma |
– |
– |
– |
Benign |
|
F8 |
53 |
F |
51 |
Uterus |
Endometrial adenocarcinoma |
3 |
Ic |
T1cN0M0 |
Malignant |
|
F9 |
54 |
F |
39 |
Uterus |
Clear cell carcinoma |
– |
IIb |
T2bN0M0 |
Malignant |
|
G1 |
55 |
F |
36 |
Uterine cervix |
Squamous cell carcinoma |
2 |
Ib |
T1bN0M0 |
Malignant |
|
G2 |
56 |
F |
35 |
Uterine cervix |
Squamous cell carcinoma |
2–3 |
Ia |
T1a2N0M0 |
Malignant |
|
G3 |
57 |
F |
20 |
Striated muscle |
Embryonal rhabdomyosarcom of left leg |
– |
Ia |
T1aN0M0 |
Malignant |
|
G4 |
58 |
F |
70 |
Rectum |
Malignant melanoma of rectum |
– |
II |
T4N0M0 |
Malignant |
|
G5 |
59 |
F |
64 |
Skin |
Basal cell carcinoma of head |
– |
II |
T2N0M0 |
Malignant |
|
G6 |
60 |
M |
46 |
Skin |
Squamous cell carcinoma of left chest wall |
2 |
II |
T3N0M0 |
Malignant |
|
G7 |
61 |
M |
59 |
Soft tissue |
Neurofibroma of left waist |
– |
– |
– |
Benign |
|
G8 |
62 |
F |
3 |
Retroperitoneum |
Ganglioneuroblastoma |
– |
– |
– |
Malignant |
|
G9 |
63 |
M |
48 |
Abdominal cavity |
Malignant mesothelioma |
– |
– |
– |
Malignant |
|
H1 |
64 |
F |
48 |
Lymph node |
Diffuse large B-cell lymphoma of right oxter |
– |
– |
– |
Malignant |
|
H2 |
65 |
F |
50 |
Lymph node |
Diffuse B cell lymphoma of right thigh |
– |
– |
– |
Malignant |
|
H3 |
66 |
M |
53 |
Lymph node |
Hodgkin's lymphoma over right clavicle |
– |
– |
– |
Malignant |
|
H4 |
67 |
F |
68 |
Lymph node |
Diffuse malignant lymphoma of mandible |
– |
– |
– |
Malignant |
|
H5 |
68 |
F |
72 |
Bladder |
Transitional cell carcinoma |
3 |
II |
T2N0M0 |
Malignant |
|
H6 |
69 |
M |
62 |
Bladder |
Leiomyosarcoma |
– |
IIb |
T2N0M0 |
Malignant |
|
H7 |
70 |
F |
7 |
Bone |
Osteosarcoma of right femur inferior extremity |
– |
IIIb |
T2N0M0 |
Malignant |
|
H8 |
71 |
F |
48 |
Retroperitoneum |
Spindle cell rhabdomyosarcoma of retroperitoneum |
– |
IIb |
T2N0M0 |
Malignant |
|
H9 |
72 |
F |
60 |
Smooth muscle |
Intermediate grade malignant leiomyosarcoma of left buttock |
– |
IIIb |
T2bN0M0 |
Malignant |
|
–
|
– |
M |
58 |
Skin |
Malignant melanoma (tissue marker) |
– |
|
|
Malignant |
† For precise diagnosis, refer to pathology description.
**The grade 1-3 (or I-III) in Pathology Diagnosis is equivalent to well-differentiated, moderately-differentiated or poorly differentiated, respectively, under microscope.
Grade 1 or well-differentiated: Cells appear normal and are not growing rapidly.
Grade 2 or moderately-differentiated: Cells appear slightly different than normal.
Grade 3 or poorly differentiated: Cells appear abnormal and tend to grow and spread more aggressively.
Grade 4 or undifferentiated: *(for certain tumors), features are not significantly distinguishing to make it look any different from undifferentiated cancers which occur in other organs.
TNM grading:
T - Primary tumor
Tx - Primary tumor cannot be assessed
T0 - No evidence of primary tumor
Tis - Carcinoma in situ; intraepithelial or invasion of lamina propria
T1 - Tumor invades submucosa
T2 - Tumor invades muscularis propria
T3 - Tumor invades through muscularis propria into subserosa or into non-peritonealized pericolic or perirectal tissues.
T4 - Tumor directly invades other organs or structures and/or perforate visceral peritoneum
N - Regional lymph nodes
Nx - Regional lymph nodes cannot be assessed
N0 - No regional lymph node metastasis
N1 - Metastasis in 1 to 3 regional lymph nodes
N2 - Metastasis in 4 or more regional lymph nodes
M - Distant metastasis
Mx - Distant metastasis cannot be assessed
M0 - No distant metastasis
M1 - Distant metastasis
|
|