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FDA805-2
Multiple organ cancer and 6 types of normal organ tissue array, including TNM and pathology grade, 72 cases/72 cores, replaced by FDA808-2
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| Microarray Panel: | Multiple organ carcinoma and normal tissue microarray, containing 6 types normal organ, single core per case, for FDA guidelines to test tissue specificity of antibodies，also including 54 cases of various carcinomas. |
| Cores: | 72 |
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| Cases: | 72 |
| Layout: | 9 cols × 8 rows |
| Core Diameter: | 1.5 mm |
| Thickness: | 5 µm | | Quality Control: | Anti-Actin confirmed | | Applications: | Routine histology procedures including ImmunoHistochemistry (IHC) and In Situ Hybridization (ISH), protocols which can be found on our support page. |
| Notes: | Unless specified, all TMA slides are not coated with extra layer of paraffin (tissue cores can be easily seen on the glass), so there is no need to bake, can be directly put into xylene for de-paraffin procedure. |
*Tissue Microarray Slide Types:
- Unstained: unstained
paraffin
tissue microarray slide.
- Trial: tissue microarray trial slide. 10% - 25% of cores missing. Good for titrating antibody dilution and experiment conditions. Limited numbers are available, to 2 per item per order. Test slides (tissue arrays with catalog numbers ending with 241 or 242) are recommended as a substitute.
- H & E: Hematoxylin and Eosin stained tissue microarray slide.
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| Legend: | Bla - Bladder,
Bon - Bone,
Bra - Brain,
Bre - Breast,
Col - Colon,
End - Endometrium,
Eso - Esophagus,
Kid - Kidney,
Liv - Liver,
Lun - Lung,
Lym - Lymph node,
Med - Mediastinum,
Mes - Mesothelium,
Ner - Nerve,
Ova - Ovary,
Pan - Pancreas,
Per - Peritoneum,
Pro - Prostate,
Rec - Rectum,
Ret - Retroperitoneum,
Ski - Skin,
Sma - Small intestine,
Sof - Soft tissue,
Spl - Spleen,
Sto - Stomach,
Tes - Testis,
Thr - Thyroid,
Ute - Uterine cervix
 - Benign tumor,
 - Malignant tumor,
 - Malignant tumor,
 - Malignant tumor (stage I),
 - Malignant tumor (stage II),
 - Malignant tumor (stage III),
 - Malignant tumor (stage IIIa),
 - Malignant tumor (stage IIIb),
 - Malignant tumor (stage IIIc),
 - Malignant tumor (stage IIa),
 - Malignant tumor (stage IIb),
 - Malignant tumor (stage Ib),
 - Malignant tumor (stage Ic),
 - Normal tissue
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Specification Sheet
| Pos |
No. |
Sex |
Age |
Organ |
Pathology diagnosis |
Grade |
Stage |
TNM |
Type † |
|
A1 |
1 |
F |
40 |
Endometrium |
Normal endometrium tissue |
– |
– |
– |
Normal |
|
A2 |
2 |
F |
21 |
Endometrium |
Normal endometrium tissue |
– |
– |
– |
Normal |
|
A3 |
3 |
F |
18 |
Endometrium |
Normal endometrium tissue |
– |
– |
– |
Normal |
|
A4 |
4 |
F |
48 |
Uterine cervix |
Normal uterine cervix tissue |
– |
– |
– |
Normal |
|
A5 |
5 |
F |
21 |
Uterine cervix |
Normal uterine cervix tissue |
– |
– |
– |
Normal |
|
A6 |
6 |
F |
35 |
Uterine cervix |
Normal uterine cervix tissue |
– |
– |
– |
Normal |
|
A7 |
7 |
M |
38 |
Soft tissue |
Normal skeletal muscle tissue |
– |
– |
– |
Normal |
|
A8 |
8 |
M |
30 |
Soft tissue |
Normal skeletal muscle tissue |
– |
– |
– |
Normal |
|
A9 |
9 |
M |
40 |
Soft tissue |
Normal skeletal muscle tissue |
– |
– |
– |
Normal |
|
B1 |
10 |
F |
42 |
Skin |
Normal skin tissue |
– |
– |
– |
Normal |
|
B2 |
11 |
M |
19 |
Skin |
Normal skin tissue |
– |
– |
– |
Normal |
|
B3 |
12 |
M |
30 |
Skin |
Normal skin tissue |
– |
– |
– |
Normal |
|
B4 |
13 |
F |
15 |
Nerve |
Normal nervous tissue (sparse) |
– |
– |
– |
Normal |
|
B5 |
14 |
F |
25 |
Nerve |
Normal nervous tissue |
– |
– |
– |
Normal |
|
B6 |
15 |
F |
62 |
Nerve |
Normal nervous tissue |
– |
– |
– |
Normal |
|
B7 |
16 |
M |
48 |
Mesothelium |
Normal mesothelium tissue (lung tissue) |
– |
– |
– |
Normal |
|
B8 |
17 |
M |
22 |
Mesothelium |
Normal mesothelial and lung tissue |
– |
– |
– |
Normal |
|
B9 |
18 |
M |
40 |
Mesothelium |
Normal mesothelium tissue (lung tissue) |
– |
– |
– |
Normal |
|
C1 |
19 |
M |
39 |
Brain |
Glioblastoma |
– |
– |
– |
Malignant |
|
C2 |
20 |
M |
43 |
Brain |
Atypical meningioma |
– |
– |
– |
Malignant |
|
C3 |
21 |
F |
15 |
Brain |
Malignant ependymoma |
– |
– |
– |
Malignant |
|
C4 |
22 |
F |
61 |
Brain |
Malignant oligodendroglioma |
– |
– |
– |
Malignant |
|
C5 |
23 |
F |
53 |
Ovary |
Serous papillary adenocarcinoma |
3 |
IIIc |
T3N1M0 |
Malignant |
|
C6 |
24 |
F |
29 |
Ovary |
Mucinous papillary adenocarcinoma |
3 |
III |
T3N0M0 |
Malignant |
|
C7 |
25 |
F |
12 |
Pancreas |
Islet cell carcinoma |
– |
– |
– |
Malignant |
|
C8 |
26 |
M |
64 |
Pancreas |
Adenocarcinoma |
3 |
I |
T2N0M0 |
Malignant |
|
C9 |
27 |
M |
32 |
Testis |
Seminoma |
– |
I |
T1N0M0 |
Malignant |
|
D1 |
28 |
M |
30 |
Testis |
Embryonal carcinoma (fibrous tissue and blood vessel) |
– |
I |
T2N0M0 |
Malignant |
|
D2 |
29 |
F |
33 |
Thyroid |
Medullary carcinoma |
– |
II |
T3N0M0 |
Malignant |
|
D3 |
30 |
M |
36 |
Thyroid |
Papillary carcinoma |
– |
III |
T2aN1M0 |
Malignant |
|
D4 |
31 |
F |
50 |
Breast |
Intraductal carcinoma |
– |
– |
TisN0M0 |
Malignant |
|
D5 |
32 |
F |
62 |
Breast |
Lobular carcinoma in situ |
– |
– |
TisN0M0 |
Malignant |
|
D6 |
33 |
F |
39 |
Breast |
Invasive ductal carcinoma |
2 |
IIb |
T2N0M0 |
Malignant |
|
D7 |
34 |
M |
21 |
Spleen |
Diffuse B-cell lymphoma |
– |
– |
– |
Malignant |
|
D8 |
35 |
F |
45 |
Lung |
Small cell undifferentiated carcinoma |
– |
IIIa |
T3N2M0 |
Malignant |
|
D9 |
36 |
M |
74 |
Lung |
Squamous cell carcinoma |
3 |
II |
T2N1M0 |
Malignant |
|
E1 |
37 |
F |
59 |
Lung |
Adenocarcinoma |
2 |
II |
T2N1M0 |
Malignant |
|
E2 |
38 |
M |
50 |
Esophagus |
Squamous cell carcinoma |
2 |
IIa |
T2N1M0 |
Malignant |
|
E3 |
39 |
F |
67 |
Esophagus |
Adenocarcinoma |
3 |
III |
T4N0M0 |
Malignant |
|
E4 |
40 |
F |
73 |
Stomach |
Mucinous adenocarcinoma |
3 |
IIIa |
T3N1M0 |
Malignant |
|
E5 |
41 |
M |
50 |
Small intestine |
Adenocarcinoma |
2 |
II |
T3N0M0 |
Malignant |
|
E6 |
42 |
F |
71 |
Small intestine |
Intermediate grade malignant interstitialoma |
– |
IIb |
T2bN0M0 |
Malignant |
|
E7 |
43 |
M |
70 |
Colon |
Adenocarcinoma |
2 |
II |
T3N1M0 |
Malignant |
|
E8 |
44 |
M |
54 |
Colon |
Intermediate grade malignant interstitialoma |
– |
IIb |
T2N0M0 |
Malignant |
|
E9 |
45 |
F |
50 |
Rectum |
Adenocarcinoma |
2 |
II |
T3N1M0 |
Malignant |
|
F1 |
46 |
M |
32 |
Rectum |
Intermediate grade malignant interstitialoma |
– |
IIa |
T1bN0M0 |
Malignant |
|
F2 |
47 |
M |
61 |
Liver |
Hepatocellular carcinoma |
2 |
II |
T2N0M0 |
Malignant |
|
F3 |
48 |
F |
17 |
Liver |
Hepatoblastoma |
– |
– |
– |
Malignant |
|
F4 |
49 |
M |
55 |
Kidney |
Clear cell carcinoma |
2 |
II |
T2N0M0 |
Malignant |
|
F5 |
50 |
M |
67 |
Prostate |
Adenocarcinoma (Gleason grade:5 Gleason score:4+5) |
3 |
II |
T2N0M0 |
Malignant |
|
F6 |
51 |
M |
81 |
Prostate |
Transitional cell carcinoma |
2 |
III |
T4N0M0 |
Malignant |
|
F7 |
52 |
F |
45 |
Endometrium |
Leiomyoma |
– |
– |
– |
Benign |
|
F8 |
53 |
F |
51 |
Endometrium |
Endometrial adenocarcinoma |
3 |
Ic |
T1cN0M0 |
Malignant |
|
F9 |
54 |
F |
39 |
Endometrium |
Clear cell carcinoma of endometrium with necrosis |
– |
IIb |
T2bN0M0 |
Malignant |
|
G1 |
55 |
F |
36 |
Uterine cervix |
Squamous cell carcinoma |
3 |
IIIb |
T1bN1M0 |
Malignant |
|
G2 |
56 |
F |
41 |
Uterine cervix |
Squamous cell carcinoma |
3 |
IIIb |
T1b1N1M0 |
Malignant |
|
G3 |
57 |
F |
20 |
Soft tissue |
Embryonal rhabdomyosarcom of left leg |
– |
IIIa |
T1aN1M0 |
Malignant |
|
G4 |
58 |
F |
70 |
Rectum |
Malignant melanoma of anus (necrotic tissue) |
– |
– |
– |
Malignant |
|
G5 |
59 |
F |
65 |
Skin |
Basal cell carcinoma of head |
– |
II |
T2N0M0 |
Malignant |
|
G6 |
60 |
M |
46 |
Skin |
Squamous cell carcinoma of left chest wall |
2 |
II |
T3N0M0 |
Malignant |
|
G7 |
61 |
M |
59 |
Mediastinum |
Neurofibroma |
– |
– |
– |
Malignant |
|
G8 |
62 |
F |
3 |
Retroperitoneum |
Neuroblastoma of retroperitoneum |
– |
IIIb |
T2bN0M0 |
Malignant |
|
G9 |
63 |
M |
60 |
Peritoneum |
Malignant mesothelioma |
– |
– |
– |
Malignant |
|
H1 |
64 |
M |
42 |
Lymph node |
Diffuse malignant lymphoma |
– |
– |
– |
Malignant |
|
H2 |
65 |
F |
50 |
Lymph node |
Diffuse malignant B cell lymphoma of right thigh |
– |
– |
– |
Malignant |
|
H3 |
66 |
M |
53 |
Lymph node |
Hodgkin's lymphoma |
– |
– |
– |
Malignant |
|
H4 |
67 |
F |
68 |
Lymph node |
Diffuse malignant lymphoma of mandible |
– |
– |
– |
Malignant |
|
H5 |
68 |
F |
72 |
Bladder |
Transitional cell carcinoma |
3 |
II |
T2N0M0 |
Malignant |
|
H6 |
69 |
M |
62 |
Bladder |
Low grade malignant leiomyosarcoma |
– |
Ib |
T2bN0M0 |
Malignant |
|
H7 |
70 |
F |
7 |
Bone |
Osteosarcoma of right femur inferior extremity |
– |
IIIb |
T2N0M0 |
Malignant |
|
H8 |
71 |
F |
48 |
Retroperitoneum |
Spindle cell rhabdomyosarcoma |
– |
IIb |
T2N0M0 |
Malignant |
|
H9 |
72 |
F |
60 |
Soft tissue |
Intermediate grade malignant leiomyosarcoma of left buttock |
– |
IIb |
T2bN0M0 |
Malignant |
|
–
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– |
M |
58 |
Skin |
Malignant melanoma (tissue marker) |
– |
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Malignant |
† For precise diagnosis, refer to pathology description.
**The grade 1-3 (or I-III) in Pathology Diagnosis is equivalent to well-differentiated, moderately-differentiated or poorly differentiated, respectively, under microscope.
Grade 1 or well-differentiated: Cells appear normal and are not growing rapidly.
Grade 2 or moderately-differentiated: Cells appear slightly different than normal.
Grade 3 or poorly differentiated: Cells appear abnormal and tend to grow and spread more aggressively.
Grade 4 or undifferentiated: *(for certain tumors), features are not significantly distinguishing to make it look any different from undifferentiated cancers which occur in other organs.
TNM grading:
T - Primary tumor
Tx - Primary tumor cannot be assessed
T0 - No evidence of primary tumor
Tis - Carcinoma in situ; intraepithelial or invasion of lamina propria
T1 - Tumor invades submucosa
T2 - Tumor invades muscularis propria
T3 - Tumor invades through muscularis propria into subserosa or into non-peritonealized pericolic or perirectal tissues.
T4 - Tumor directly invades other organs or structures and/or perforate visceral peritoneum
N - Regional lymph nodes
Nx - Regional lymph nodes cannot be assessed
N0 - No regional lymph node metastasis
N1 - Metastasis in 1 to 3 regional lymph nodes
N2 - Metastasis in 4 or more regional lymph nodes
M - Distant metastasis
Mx - Distant metastasis cannot be assessed
M0 - No distant metastasis
M1 - Distant metastasis
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