US Biomax, Inc.

FDA805

FDA normal and tumor organ tissue array of human (2 slide set) for FDA guidelines to test tissue specificity of antibodies, replacing FDA804, 144 cases/144 cores

FDA805-1

FDA multiple organ normal tissue array of human, 53 cases/72 cores, replacing FDA804-1

Microarray Panel:FDA multiple organ normal microarray of human, 24 types of normal organs, each type taken from 3 normal human individuals, single core format, for FDA guidelines to test tissue specificity of antibodies.
Cores:72
Cases:53
Layout:9 cols × 8 rows
Core Diameter:1.5 mm
Thickness:5 µm
Applications:Routine histology procedures including ImmunoHistochemistry (IHC) and In Situ Hybridization (ISH), protocols which can be found on our support page.
Notes:1. Some slides are covered by a thin layer of paraffin to prevent oxidization and decay, thus are recommended be baked at 56-60°C up to 2 hours until the paraffin melt before doing regular IHC or ISH procedures.
2. For slides not coated with paraffin (those tissue cores can be easily seen on the glass), there is no need to bake, can be directly put into xylene for de-paraffin procedure.


Microarray Panel Display

 
Slide Label: US Biomax, Inc. Tissue Array
123456789 
A Cer Cer Cer Cer Cer Cer Adr Adr Adr  
B Ova Ova Ova Pan Pan Pan Par Par Par  
C Hyp Hyp Hyp Tes Tes Tes Thr Thr Thr  
D Bre Bre Bre Spl Spl Spl Ton Ton Ton  
E Thy Thy Thy Bon Bon Bon Lun Lun Lun  
F Hea Hea Hea Eso Eso Eso Sto Sto Sto  
G Sma Sma Sma Col Col Col Liv Liv Liv  
H Sal Sal Sal Kid Kid Kid Pro Pro Pro Marked point
Legend: Adr - Adrenal gland, Bon - Bone, Bre - Breast, Cer - Cerebellum, Col - Colon, Eso - Esophagus, Hea - Heart, Hyp - Hypophysis, Kid - Kidney, Liv - Liver, Lun - Lung, Ova - Ovary, Pan - Pancreas, Par - Parathyroid gland, Pro - Prostate, Sal - Salivary gland, Sma - Small intestine, Spl - Spleen, Sto - Stomach, Tes - Testis, Thr - Thyroid, Thy - Thymus gland, Ton - Tonsil

- Malignant tumor, - Normal tissue

Specification Sheet

Pos No. Sex Age Organ Pathology diagnosis Type †
A1 1 F 2 Cerebrum Normal cerebrum tissue Normal
A2 2 F 50 Cerebrum Normal cerebrum tissue Normal
A3 3 F 42 Cerebrum Normal cerebrum tissue Normal
A4 4 F 24 Cerebellum Normal cerebellum tissue Normal
A5 5 F 58 Cerebellum Normal cerebellum tissue Normal
A6 6 F 8 Cerebellum Normal cerebellum tissue Normal
A7 7 F 14 Adrenal gland Normal adrenal gland tissue Normal
A8 8 M 1 Mon. Adrenal gland Normal adrenal gland tissue Normal
A9 9 M 5 Mon. Adrenal gland Normal adrenal gland tissue Normal
B1 10 F 19 Ovary Normal ovary tissue Normal
B2 11 F 20 Ovary Normal ovary tissue Normal
B3 12 F 18 Ovary Normal ovary tissue Normal
B4 13 F 35 Pancreas Normal pancreas tissue Normal
B5 14 M 1 Mon. Pancreas Normal pancreas tissue Normal
B6 15 F 52 Pancreas Normal pancreas tissue Normal
B7 16 F 50 Parathyroid gland Normal parathyroid gland tissue (thyroid gland tissue) Normal
B8 17 F 40 Parathyroid gland Normal parathyroid gland tissue (thyroid gland tissue) Normal
B9 18 F 40 Parathyroid gland Normal parathyroid gland tissue (thyroid gland tissue) Normal
C1 19 F 15 Hypophysis Normal hypophysis tissue Normal
C2 20 F 18 Hypophysis Normal hypophysis tissue Normal
C3 21 M 15 Hypophysis Normal hypophysis tissue Normal
C4 22 M 30 Testis Normal testis tissue Normal
C5 23 M 74 Testis Normal testis tissue Normal
C6 24 M 65 Testis Normal testis tissue Normal
C7 25 F 25 Thyroid Normal thyroid tissue Normal
C8 26 M 37 Thyroid Normal thyroid tissue Normal
C9 27 M 22 Thyroid Normal thyroid tissue Normal
D1 28 F 35 Breast Normal breast tissue Normal
D2 29 F 32 Breast Normal breast tissue Normal
D3 30 F 33 Breast Normal breast tissue Normal
D4 31 F 2 Spleen Normal spleen tissue Normal
D5 32 M 35 Spleen Normal spleen tissue Normal
D6 33 M 30 Spleen Normal spleen tissue Normal
D7 34 F 15 Tonsil Normal tonsil tissue Normal
D8 35 M 35 Tonsil Normal tonsil tissue Normal
D9 36 F 18 Tonsil Normal tonsil tissue Normal
E1 37 M 0 Thymus gland Normal thymus tissue Normal
E2 38 F 15 Thymus gland Normal thymus tissue Normal
E3 39 F 18 Thymus gland Normal thymus tissue Normal
E4 40 M 56 Bone Normal myeloid tissue Normal
E5 41 F 61 Bone Normal myeloid tissue Normal
E6 42 M 70 Bone Normal myeloid tissue Normal
E7 43 M 24 Lung Normal lung tissue Normal
E8 44 M 42 Lung Normal lung tissue Normal
E9 45 M 48 Lung Normal lung tissue Normal
F1 46 M 56 Heart Normal myocardial tissue Normal
F2 47 F 42 Heart Normal myocardial tissue Normal
F3 48 F 35 Heart Normal myocardial tissue Normal
F4 49 M 35 Esophagus Normal esophagus tissue Normal
F5 50 M 24 Esophagus Normal esophagus tissue Normal
F6 51 F 42 Esophagus Normal esophagus tissue Normal
F7 52 M 48 Stomach Normal stomach tissue Normal
F8 53 M 35 Stomach Normal stomach tissue Normal
F9 54 M 40 Stomach Normal stomach tissue Normal
G1 55 M 40 Small intestine Normal small intestine tissue Normal
G2 56 F 38 Small intestine Normal small intestine tissue Normal
G3 57 M 35 Small intestine Normal small intestine tissue Normal
G4 58 M 62 Colon Normal colon tissue Normal
G5 59 F 42 Colon Normal colon tissue Normal
G6 60 M 35 Colon Normal colon tissue (smooth muscle tissue) Normal
G7 61 M 40 Liver Normal liver tissue Normal
G8 62 F 35 Liver Normal liver tissue Normal
G9 63 M 35 Liver Normal liver tissue Normal
H1 64 M 50 Salivary gland Normal salivary gland tissue Normal
H2 65 M 77 Salivary gland Normal salivary gland tissue Normal
H3 66 M 28 Salivary gland Normal salivary gland tissue Normal
H4 67 F 14 Kidney Normal kidney tissue Normal
H5 68 M 48 Kidney Normal kidney tissue Normal
H6 69 F 50 Kidney Normal kidney tissue Normal
H7 70 M 27 Prostate Normal prostate tissue Normal
H8 71 M 25 Prostate Normal prostate tissue Normal
H9 72 M 28 Prostate Normal prostate tissue Normal
M 58 Skin Malignant melanoma (tissue marker) Malignant

† For precise diagnosis, refer to pathology description.


Find overlapping cases with this tissue array:

FDA805-2

Multiple organ cancer and 6 types of normal organ tissue array, including TNM and pathology grade, 72 cases/72 cores, replacing FDA804-2

Microarray Panel:Multiple organ carcinoma and normal tissue microarray, containing 6 types normal organ, single core per case, for FDA guidelines to test tissue specificity of antibodies,also including 54 cases of various carcinomas.
Cores:72
Cases:72
Layout:9 cols × 8 rows
Core Diameter:1.5 mm
Thickness:5 µm
Applications:Routine histology procedures including ImmunoHistochemistry (IHC) and In Situ Hybridization (ISH), protocols which can be found on our support page.
Notes:1. Some slides are covered by a thin layer of paraffin to prevent oxidization and decay, thus are recommended be baked at 56-60°C up to 2 hours until the paraffin melt before doing regular IHC or ISH procedures.
2. For slides not coated with paraffin (those tissue cores can be easily seen on the glass), there is no need to bake, can be directly put into xylene for de-paraffin procedure.


Microarray Panel Display

 
Slide Label: US Biomax, Inc. Tissue Array
123456789 
A End End End Ute Ute Ute Sof Sof Sof  
B Ski Ski Ski Ner Ner Ner Mes Mes Mes  
C Bra Bra Bra Bra Ova Ova Pan Pan Tes  
D Tes Thr Thr Bre Bre Bre Spl Lun Lun  
E Lun Eso Eso Sto Sma Sma Col Col Rec  
F Rec Liv Liv Kid Pro Pro End End End  
G Ute Ute Sof Rec Ski Ski Med Ret Per  
H Lym Lym Lym Lym Bla Bla Bon Ret Sof Marked point
Legend: Bla - Bladder, Bon - Bone, Bra - Brain, Bre - Breast, Col - Colon, End - Endometrium, Eso - Esophagus, Kid - Kidney, Liv - Liver, Lun - Lung, Lym - Lymph node, Med - Mediastinum, Mes - Mesothelium, Ner - Nerve, Ova - Ovary, Pan - Pancreas, Per - Peritoneum, Pro - Prostate, Rec - Rectum, Ret - Retroperitoneum, Ski - Skin, Sma - Small intestine, Sof - Soft tissue, Spl - Spleen, Sto - Stomach, Tes - Testis, Thr - Thyroid, Ute - Uterine cervix

- Benign tumor, - Malignant tumor, - Malignant tumor, - Malignant tumor (stage I), - Malignant tumor (stage II), - Malignant tumor (stage III), - Malignant tumor (stage IIIa), - Malignant tumor (stage IIIb), - Malignant tumor (stage IIIc), - Malignant tumor (stage IIa), - Malignant tumor (stage IIb), - Malignant tumor (stage Ib), - Malignant tumor (stage Ic), - Normal tissue

Specification Sheet

Pos No. Sex Age Organ Pathology diagnosis Grade Stage TNM Type †
A1 1 F 40 Endometrium Normal endometrium tissue Normal
A2 2 F 21 Endometrium Normal endometrium tissue Normal
A3 3 F 18 Endometrium Normal endometrium tissue Normal
A4 4 F 48 Uterine cervix Normal uterine cervix tissue Normal
A5 5 F 21 Uterine cervix Normal uterine cervix tissue Normal
A6 6 F 35 Uterine cervix Normal uterine cervix tissue Normal
A7 7 M 38 Soft tissue Normal skeletal muscle tissue Normal
A8 8 M 30 Soft tissue Normal skeletal muscle tissue Normal
A9 9 M 40 Soft tissue Normal skeletal muscle tissue Normal
B1 10 F 42 Skin Normal skin tissue Normal
B2 11 M 19 Skin Normal skin tissue Normal
B3 12 M 30 Skin Normal skin tissue Normal
B4 13 F 15 Nerve Normal nervous tissue (sparse) Normal
B5 14 F 25 Nerve Normal nervous tissue Normal
B6 15 F 62 Nerve Normal nervous tissue Normal
B7 16 M 48 Mesothelium Normal mesothelium tissue (lung tissue) Normal
B8 17 M 22 Mesothelium Normal mesothelial and lung tissue Normal
B9 18 M 40 Mesothelium Normal mesothelium tissue (lung tissue) Normal
C1 19 M 39 Brain Glioblastoma Malignant
C2 20 M 43 Brain Atypical meningioma Malignant
C3 21 F 15 Brain Malignant ependymoma Malignant
C4 22 F 61 Brain Malignant oligodendroglioma Malignant
C5 23 F 53 Ovary Serous papillary adenocarcinoma 3 IIIc T3N1M0 Malignant
C6 24 F 29 Ovary Mucinous papillary adenocarcinoma 3 III T3N0M0 Malignant
C7 25 F 12 Pancreas Islet cell carcinoma Malignant
C8 26 M 64 Pancreas Adenocarcinoma 3 I T2N0M0 Malignant
C9 27 M 32 Testis Seminoma I T1N0M0 Malignant
D1 28 M 30 Testis Embryonal carcinoma (fibrous tissue and blood vessel) I T2N0M0 Malignant
D2 29 F 33 Thyroid Medullary carcinoma II T3N0M0 Malignant
D3 30 M 36 Thyroid Papillary carcinoma III T2aN1M0 Malignant
D4 31 F 50 Breast Intraductal carcinoma TisN0M0 Malignant
D5 32 F 62 Breast Lobular carcinoma in situ TisN0M0 Malignant
D6 33 F 39 Breast Invasive ductal carcinoma 2 IIb T2N0M0 Malignant
D7 34 M 21 Spleen Diffuse B-cell lymphoma Malignant
D8 35 F 45 Lung Small cell undifferentiated carcinoma IIIa T3N2M0 Malignant
D9 36 M 74 Lung Squamous cell carcinoma 3 II T2N1M0 Malignant
E1 37 F 59 Lung Adenocarcinoma 2 II T2N1M0 Malignant
E2 38 M 50 Esophagus Squamous cell carcinoma 2 IIa T2N1M0 Malignant
E3 39 F 67 Esophagus Adenocarcinoma 3 III T4N0M0 Malignant
E4 40 F 73 Stomach Mucinous adenocarcinoma 3 IIIa T3N1M0 Malignant
E5 41 M 50 Small intestine Adenocarcinoma 2 II T3N0M0 Malignant
E6 42 F 71 Small intestine Intermediate grade malignant interstitialoma IIb T2bN0M0 Malignant
E7 43 M 70 Colon Adenocarcinoma 2 II T3N1M0 Malignant
E8 44 M 54 Colon Intermediate grade malignant interstitialoma IIb T2N0M0 Malignant
E9 45 F 50 Rectum Adenocarcinoma 2 II T3N1M0 Malignant
F1 46 M 32 Rectum Intermediate grade malignant interstitialoma IIa T1bN0M0 Malignant
F2 47 M 61 Liver Hepatocellular carcinoma 2 II T2N0M0 Malignant
F3 48 F 17 Liver Hepatoblastoma Malignant
F4 49 M 55 Kidney Clear cell carcinoma 2 II T2N0M0 Malignant
F5 50 M 67 Prostate Adenocarcinoma (Gleason grade:5 Gleason score:4+5) 3 II T2N0M0 Malignant
F6 51 M 81 Prostate Transitional cell carcinoma 2 III T4N0M0 Malignant
F7 52 F 45 Endometrium Leiomyoma Benign
F8 53 F 51 Endometrium Endometrial adenocarcinoma 3 Ic T1cN0M0 Malignant
F9 54 F 39 Endometrium Clear cell carcinoma of endometrium with necrosis IIb T2bN0M0 Malignant
G1 55 F 36 Uterine cervix Squamous cell carcinoma 3 IIIb T1bN1M0 Malignant
G2 56 F 41 Uterine cervix Squamous cell carcinoma 3 IIIb T1b1N1M0 Malignant
G3 57 F 20 Soft tissue Embryonal rhabdomyosarcom of left leg IIIa T1aN1M0 Malignant
G4 58 F 70 Rectum Malignant melanoma of anus (necrotic tissue) Malignant
G5 59 F 65 Skin Basal cell carcinoma of head II T2N0M0 Malignant
G6 60 M 46 Skin Squamous cell carcinoma of left chest wall 2 II T3N0M0 Malignant
G7 61 M 59 Mediastinum Neurofibroma Malignant
G8 62 F 3 Retroperitoneum Neuroblastoma of retroperitoneum IIIb T2bN0M0 Malignant
G9 63 M 60 Peritoneum Malignant mesothelioma Malignant
H1 64 M 42 Lymph node Diffuse malignant lymphoma Malignant
H2 65 F 50 Lymph node Diffuse malignant B cell lymphoma of right thigh Malignant
H3 66 M 53 Lymph node Hodgkin's lymphoma Malignant
H4 67 F 68 Lymph node Diffuse malignant lymphoma of mandible Malignant
H5 68 F 72 Bladder Transitional cell carcinoma 3 II T2N0M0 Malignant
H6 69 M 62 Bladder Low grade malignant leiomyosarcoma Ib T2bN0M0 Malignant
H7 70 F 7 Bone Osteosarcoma of right femur inferior extremity IIIb T2N0M0 Malignant
H8 71 F 48 Retroperitoneum Spindle cell rhabdomyosarcoma IIb T2N0M0 Malignant
H9 72 F 60 Soft tissue Intermediate grade malignant leiomyosarcoma of left buttock IIb T2bN0M0 Malignant
M 58 Skin Malignant melanoma (tissue marker) Malignant

† For precise diagnosis, refer to pathology description.

**The grade 1-3 (or I-III) in Pathology Diagnosis is equivalent to well-differentiated, moderately-differentiated or poorly differentiated, respectively, under microscope.
Grade 1 or well-differentiated: Cells appear normal and are not growing rapidly.
Grade 2 or moderately-differentiated: Cells appear slightly different than normal.
Grade 3 or poorly differentiated: Cells appear abnormal and tend to grow and spread more aggressively.
Grade 4 or undifferentiated: *(for certain tumors), features are not significantly distinguishing to make it look any different from undifferentiated cancers which occur in other organs.

TNM grading:

T - Primary tumor
Tx - Primary tumor cannot be assessed
T0 - No evidence of primary tumor
Tis - Carcinoma in situ; intraepithelial or invasion of lamina propria
T1 - Tumor invades submucosa
T2 - Tumor invades muscularis propria
T3 - Tumor invades through muscularis propria into subserosa or into non-peritonealized pericolic or perirectal tissues.
T4 - Tumor directly invades other organs or structures and/or perforate visceral peritoneum

N - Regional lymph nodes
Nx - Regional lymph nodes cannot be assessed
N0 - No regional lymph node metastasis
N1 - Metastasis in 1 to 3 regional lymph nodes
N2 - Metastasis in 4 or more regional lymph nodes

M - Distant metastasis
Mx - Distant metastasis cannot be assessed
M0 - No distant metastasis
M1 - Distant metastasis

Find overlapping cases with this tissue array: