US Biomax, Inc.

FDA804

FDA normal and tumor organ tissue array of human (2 slide set), replaced by FDA805, 144 cases/144 cores, for FDA guidelines to test tissue specificity of antibodies

FDA804-1

Normal human organ tissue array (slide 1 of 2 slide set), replacing FDA803-1, recommended by FDA to test tissue specificity, 72 cases/72 cores, replaced by FDA805-1

Microarray Panel:FDA normal organ tissue microarray of human, 24 types of normal organs (adrenal gland, bone marrow, breast, cerebellum tissue, cerebrum, colon, esophagus, heart, hypophysis, intestine, kidney, liver, lung, ovary, pancreas, parathyroid gland, prostate, salivary gland, spleen, stomach, testis, thyroid, thymus, tonsil), each organ taken from 3 normal human individuals, together with FDA804-2 to make FDA804 set, single core per case
Cores:72
Cases:72
Layout:9 cols × 8 rows
Core Diameter:1.5 mm
Thickness:5 µm
Quality Control:Anti-Vimentin (Vim) confirmed
Applications:Routine histology procedures including ImmunoHistochemistry (IHC) and In Situ Hybridization (ISH), protocols which can be found on our support page.
Notes:Unless specified, all TMA slides are not coated with extra layer of paraffin (tissue cores can be easily seen on the glass), so there is no need to bake, can be directly put into xylene for de-paraffin procedure.


Microarray Panel Display

 
Slide Label: US Biomax, Inc. Tissue Array
123456789
A Cer Cer Cer Ceb Ceb Ceb Adr Adr Adr
B Ova Ova Ova Pan Pan Pan Par Par Par
C Hyp Hyp Hyp Tes Tes Tes Thr Thr Thr
D Bre Bre Bre Spl Spl Spl Ton Ton Ton
E Thy Thy Thy Bon Bon Bon Lun Lun Lun
F Hea Hea Hea Eso Eso Eso Sto Sto Sto
G Int Int Int Col Col Col Liv Liv Liv
H Sal Sal Sal Kid Kid Kid Pro Pro Pro
Legend: Adr - Adrenal gland, Bon - Bone marrow, Bre - Breast, Ceb - Cerebellum tissue, Cer - Cerebrum, Col - Colon, Eso - Esophagus, Hea - Heart, Hyp - Hypophysis, Int - Intestine, Kid - Kidney, Liv - Liver, Lun - Lung, Ova - Ovary, Pan - Pancreas, Par - Parathyroid gland, Pro - Prostate, Sal - Salivary gland, Spl - Spleen, Sto - Stomach, Tes - Testis, Thr - Thyroid, Thy - Thymus, Ton - Tonsil

- Normal tissue

Specification Sheet

Pos No. Sex Age Organ Pathology diagnosis Type †
A1 1 F 2 Cerebrum Normal cerebral tissue Normal
A2 2 F 50 Cerebrum Normal cerebral tissue Normal
A3 3 F 42 Cerebrum Normal cerebral tissue Normal
A4 4 F 24 Cerebellum Normal cerebellar tissue Normal
A5 5 F 58 Cerebellum Normal cerebellar tissue Normal
A6 6 F 8 Cerebellum Normal cerebellar tissue Normal
A7 7 F 14 Adrenal gland Normal adrenal gland tissue Normal
A8 8 M 1 Mon. Adrenal gland Normal adrenal gland tissue Normal
A9 9 M 5 Mon. Adrenal gland Normal adrenal gland tissue Normal
B1 10 F 14 Ovary Normal ovarial tissue Normal
B2 11 F 20 Ovary Normal ovarial tissue Normal
B3 12 F 21 Ovary Normal ovarial tissue Normal
B4 13 F 14 Pancreas Normal pancreatic tissue Normal
B5 14 F 2 Pancreas Normal pancreatic tissue Normal
B6 15 F 52 Pancreas Normal pancreatic tissue Normal
B7 16 M 43 Parathyroid gland Normal parathyroid gland tissue Normal
B8 17 F 22 Parathyroid gland Normal parathyroid tissue and thyroid gland tissue Normal
B9 18 M 45 Parathyroid gland Normal parathyroid gland tissue Normal
C1 19 F 15 Hypophysis Normal hypophysis tissue Normal
C2 20 M 20 Hypophysis Normal hypophysis tissue Normal
C3 21 F 25 Hypophysis Normal hypophysis tissue Normal
C4 22 M 30 Testis Normal testis tissue Normal
C5 23 M 65 Testis Normal testis tissue Normal
C6 24 M 74 Testis Normal testis tissue Normal
C7 25 F 25 Thyroid Normal thyroid gland tissue Normal
C8 26 M 37 Thyroid Normal thyroid gland tissue Normal
C9 27 F 58 Thyroid Normal thyroid gland tissue Normal
D1 28 F 50 Breast Normal breast tissue (fibrofatty tissue) Normal
D2 29 F 32 Breast Normal breast tissue Normal
D3 30 F 33 Breast Normal breast tissue Normal
D4 31 F 2 Spleen Normal spleen tissue Normal
D5 32 M 35 Spleen Normal spleen tissue Normal
D6 33 M 30 Spleen Normal spleen tissue Normal
D7 34 M 48 Tonsil Normal tonsilar tissue Normal
D8 35 M 35 Tonsil Normal tonsilar tissue Normal
D9 36 M 48 Tonsil Normal tonsilar tissue Normal
E1 37 M 1 Mon. Thymus Normal thymus tissue Normal
E2 38 F 2 Thymus Normal thymus tissue Normal
E3 39 M 1 Mon. Thymus Normal thymus tissue Normal
E4 40 M 56 Bone marrow Normal myeloid tissue Normal
E5 41 F 61 Bone marrow Normal myeloid tissue Normal
E6 42 M 70 Bone marrow Normal myeloid tissue Normal
E7 43 M 24 Lung Normal pulmonary tissue Normal
E8 44 M 42 Lung Normal pulmonary tissue Normal
E9 45 M 49 Lung Normal pulmonary tissue Normal
F1 46 M 56 Heart Normal myocardial tissue Normal
F2 47 F 42 Heart Normal myocardial tissue Normal
F3 48 F 35 Heart Normal myocardial tissue Normal
F4 49 M 32 Esophagus Normal esophageal tissue Normal
F5 50 F 21 Esophagus Normal esophageal tissue (smooth muscle) Normal
F6 51 F 42 Esophagus Normal esophageal tissue Normal
F7 52 M 48 Stomach Normal gastric fundus tissue Normal
F8 53 M 5 Mon. Stomach Normal gastric fundus tissue Normal
F9 54 M 40 Stomach Normal gastric fundus tissue Normal
G1 55 M 40 Intestine Normal small intestine tissue Normal
G2 56 M 38 Intestine Normal small intestine tissue Normal
G3 57 M 49 Intestine Normal small intestine tissue Normal
G4 58 M 62 Colon Normal colonic tissue Normal
G5 59 F 42 Colon Normal colonic tissue Normal
G6 60 M 35 Colon Normal colonic tissue Normal
G7 61 F 14 Liver Normal hepatic tissue Normal
G8 62 F 35 Liver Normal hepatic tissue Normal
G9 63 M 35 Liver Normal hepatic tissue Normal
H1 64 M 50 Salivary gland Normal salivary gland tissue Normal
H2 65 M 77 Salivary gland Normal salivary gland tissue Normal
H3 66 M 28 Salivary gland Normal salivary gland tissue Normal
H4 67 F 14 Kidney Normal renal tissue Normal
H5 68 M 48 Kidney Normal renal tissue Normal
H6 69 F 38 Kidney Normal renal tissue Normal
H7 70 M 27 Prostate Normal prostatic tissue Normal
H8 71 M 25 Prostate Normal prostatic tissue Normal
H9 72 M 36 Prostate Normal prostatic tissue Normal

† For precise diagnosis, refer to pathology description.


Find overlapping cases with this tissue array:

FDA804-2

Multiple tumor and 6 types of normal organ tissue array (slide 2 of 2 slide set), replacing FDA803-2, recommended by FDA to test tissue specificity, 72 cases/72 cores, replaced by FDA807-2

Microarray Panel:Multiple tumor and normal tissue microarray, 54 cases of tumor of varieties of organ tissue and 6 types of normal organ (Uterus, Cervix, Striated muscle, Skin, Nerve, Mesothelium), each organ taken from 3 normal human individuals, together with FDA804-1 to make FDA804 set, single core per case
Cores:72
Cases:72
Layout:9 cols × 8 rows
Core Diameter:1.5 mm
Thickness:5 µm
Quality Control:Anti-Actin confirmed
Applications:Routine histology procedures including ImmunoHistochemistry (IHC) and In Situ Hybridization (ISH), protocols which can be found on our support page.
Notes:Unless specified, all TMA slides are not coated with extra layer of paraffin (tissue cores can be easily seen on the glass), so there is no need to bake, can be directly put into xylene for de-paraffin procedure.


Microarray Panel Display

 
Slide Label: US Biomax, Inc. Tissue Array
123456789 
A Ute Ute Ute Ute Ute Ute Str Str Str  
B Ski Ski Ski Ner Ner Ner Mes Mes Mes  
C Bra Bra Bra Bra Ova Ova Pan Pan Tes  
D Tes Thr Thr Bre Bre Bre Spl Lun Lun  
E Lun Eso Eso Sto Sma Sma Col Col Rec  
F Rec Liv Liv Kid Pro Pro Ute Ute Ute  
G Ute Ute Str Rec Ski Ski Med Ret Per  
H Lym Lym Lym Lym Bla Bla Bon Ret Smo Marked point
Legend: Bla - Bladder, Bon - Bone, Bra - Brain, Bre - Breast, Col - Colon, Eso - Esophagus, Kid - Kidney, Liv - Liver, Lun - Lung, Lym - Lymph node, Med - Mediastinum, Mes - Mesothelium, Ner - Nerve, Ova - Ovary, Pan - Pancreas, Per - Peritoneum, Pro - Prostate, Rec - Rectum, Ret - Retroperitoneum, Ski - Skin, Sma - Small intestine, Smo - Smooth muscle, Spl - Spleen, Sto - Stomach, Str - Striated muscle, Tes - Testis, Thr - Thyroid, Ute - Uterine cervix

- Benign tumor, - Malignant tumor, - Normal tissue

Specification Sheet

Pos No. Sex Age Organ Pathology diagnosis Grade Type †
A1 1 F 21 Uterus Normal endometrial tissue Normal
A2 2 F 21 Uterus Normal endometrial tissue Normal
A3 3 F 58 Uterus Normal endometrial tissue Normal
A4 4 F 15 Uterine cervix Normal cervix tissue Normal
A5 5 F 21 Uterine cervix Normal cervix tissue Normal
A6 6 F 35 Uterine cervix Normal cervix tissue Normal
A7 7 M 40 Striated muscle Normal skeletal muscle tissue Normal
A8 8 M 30 Striated muscle Normal skeletal muscle tissue (sparse) Normal
A9 9 M 40 Striated muscle Normal skeletal muscle tissue (sparse) Normal
B1 10 M 35 Skin Normal dermatic tissue Normal
B2 11 M 40 Skin Normal dermatic tissue Normal
B3 12 M 40 Skin Normal dermatic tissue Normal
B4 13 F 15 Nerve Normal nerve tissue (sparse) Normal
B5 14 M 22 Nerve Normal nerve tissue Normal
B6 15 F 62 Nerve Normal nerve tissue (fibrous tissue and blood vessel) Normal
B7 16 M 48 Mesothelium Normal mesothelium and lung tissue (sparse) Normal
B8 17 M 22 Mesothelium Normal mesothelium and lung tissue (sparse) Normal
B9 18 M 40 Mesothelium Normal mesothelium tissue (lung tissue) Normal
C1 19 M 39 Brain Glioblastoma Malignant
C2 20 M 43 Brain Atypical meningioma Malignant
C3 21 F 15 Brain Malignant ependymoma Malignant
C4 22 F 61 Brain Malignant oligodendroglioma Malignant
C5 23 F 53 Ovary Serous papillary adenocarcinoma 3 Malignant
C6 24 F 29 Ovary Mucinous papillary adenocarcinoma 2–3 Malignant
C7 25 F 12 Pancreas Islet cell carcinoma Malignant
C8 26 M 64 Pancreas Adenocarcinoma 3 Malignant
C9 27 M 32 Testis Seminoma (sparse) Malignant
D1 28 M 30 Testis Embryonal carcinoma Malignant
D2 29 F 33 Thyroid Medullary carcinoma Malignant
D3 30 M 36 Thyroid Papillary carcinoma Malignant
D4 31 F 50 Breast Intraductal carcinoma Malignant
D5 32 F 49 Breast Lobular carcinoma in situ (breast tissue) Malignant
D6 33 F 39 Breast Invasive ductal carcinoma 2 Malignant
D7 34 M 21 Spleen Diffuse B-cell lymphoma Malignant
D8 35 F 45 Lung Small cell undifferentiated carcinoma 4 Malignant
D9 36 M 74 Lung Squamous cell carcinoma (sparse) with necrosis 3 Malignant
E1 37 F 59 Lung Adenocarcinoma 3 Malignant
E2 38 M 50 Esophagus Squamous cell carcinoma 2 Malignant
E3 39 F 67 Esophagus Adenocarcinoma 3 Malignant
E4 40 F 73 Stomach Mucinous adenocarcinoma 3 Malignant
E5 41 F 51 Small intestine Adenocarcinoma 2 Malignant
E6 42 F 71 Small intestine Intermediate grade interstitialoma Malignant
E7 43 M 70 Colon Adenocarcinoma 3 Malignant
E8 44 M 54 Colon Intermediate grade interstitialoma Malignant
E9 45 M 68 Rectum Adenocarcinoma 3 Malignant
F1 46 M 32 Rectum Intermediate grade interstitialoma Malignant
F2 47 M 61 Liver Hepatocellular carcinoma 2 Malignant
F3 48 F 17 Liver Hepatoblastoma Malignant
F4 49 M 55 Kidney Clear cell carcinoma Malignant
F5 50 M 67 Prostate Adenocarcinoma (prostate tissue sparse) Malignant
F6 51 M 66 Prostate Transitional cell carcinoma 3 Malignant
F7 52 F 45 Uterus Leiomyoma Malignant
F8 53 F 48 Uterus Endometrial adenocarcinoma 3 Malignant
F9 54 F 39 Uterus Clear cell carcinoma of endometrium Malignant
G1 55 F 36 Uterine cervix Squamous cell carcinoma 3 Malignant
G2 56 F 39 Uterine cervix Squamous cell carcinoma 3 Malignant
G3 57 F 20 Striated muscle Embryonal rhabdomyosarcom of left leg Malignant
G4 58 F 70 Rectum Malignant melanoma of anus Malignant
G5 59 F 65 Skin Basal cell carcinoma of head Malignant
G6 60 M 46 Skin Squamous cell carcinoma of left chest wall 2 Malignant
G7 61 M 59 Mediastinum Neurofibroma Benign
G8 62 F 3 Retroperitoneum Neuroblastoma of retroperitoneum Malignant
G9 63 M 60 Peritoneum Epithelial malignant mesothelioma Malignant
H1 64 M 42 Lymph node Diffuse malignant lymphoma Malignant
H2 65 M 53 Lymph node Diffuse malignant lymphoma Malignant
H3 66 M 53 Lymph node Hodgkin's lymphoma of supraclavicular Malignant
H4 67 F 68 Lymph node Diffuse malignant lymphoma of mandible Malignant
H5 68 F 72 Bladder Transitional cell carcinoma with squamous metaplasia 3 Malignant
H6 69 M 62 Bladder Low grade leiomyosarcoma Malignant
H7 70 F 7 Bone Osteosarcoma of right femur inferior extremity Malignant
H8 71 F 48 Retroperitoneum Spindle cell rhabdomyosarcoma of retroperitoneum Malignant
H9 72 F 60 Smooth muscle Intermediate grade leiomyosarcoma of left buttock Malignant
M 58 Skin Malignant melanoma (tissue marker) Malignant
"-" No grading available. *Tissue dots may be missing or histologically unidentifiable

† For precise diagnosis, refer to pathology description.

**The grade 1-3 (or I-III) in Pathology Diagnosis is equivalent to well-differentiated, moderately-differentiated or poorly differentiated, respectively, under microscope.
Grade 1 or well-differentiated: Cells appear normal and are not growing rapidly.
Grade 2 or moderately-differentiated: Cells appear slightly different than normal.
Grade 3 or poorly differentiated: Cells appear abnormal and tend to grow and spread more aggressively.
Grade 4 or undifferentiated: *(for certain tumors), features are not significantly distinguishing to make it look any different from undifferentiated cancers which occur in other organs.


Find overlapping cases with this tissue array: