US Biomax, Inc.

LV20812a

Liver disease spectrum tissue array, including HBV infection information, TNM and pathology grade, 96 cases/192 cores, replacing LV20812

Microarray Panel:Liver disease spectrum tissue microarray with HBV infection information, containing 16 cases of normal liver tissue, 24 hepatitis, 28 hepatic cirrhosis and 28 hepatocellular carcinoma, duplicate cores per case
Cores:192
Cases:96
Layout:16 cols × 12 rows
Core Diameter:1 mm
Thickness:5 µm
Quality Control:H&E and IHC confirmed
Applications:

Routine histology procedures including Immunohistochemistry (IHC) and In Situ Hybridization (ISH), protocols which can be found at our support page.

Notes:1. TMA slides were sectioned and stored at 4°C and may not be fresh cut, but still suitable for IHC. Please request fresh cut if experiment involves phospho-specific antibodies, RNA studies, FISH or ISH, etc. A minimum of 3 slides per TMA must be purchased to cover the cost of trimming for fresh sectioning.
2. Most of the TMA slides were not coated with an extra layer of paraffin (tissue cores can be easily seen on the glass). We still recommend 30 minutes of baking at 60°C before putting into xylene for de-paraffinization procedure.

Specification Sheet

Pos No. Sex Age Organ Pathology diagnosis Grade TNM HBV Type †
A1 1 M 45 Liver Liver tissue No info Normal
A2 2 M 45 Liver Liver tissue No info Normal
A3 3 M 36 Liver Liver tissue No info Normal
A4 4 M 36 Liver Liver tissue No info Normal
A5 5 F 35 Liver Liver tissue No info Normal
A6 6 F 35 Liver Liver tissue No info Normal
A7 7 M 43 Liver Liver tissue No info Normal
A8 8 M 43 Liver Liver tissue No info Normal
A9 9 M 40 Liver Liver tissue No info Normal
A10 10 M 40 Liver Liver tissue No info Normal
A11 11 M 27 Liver Liver tissue No info Normal
A12 12 M 27 Liver Liver tissue No info Normal
A13 13 M 40 Liver Liver tissue No info Normal
A14 14 M 40 Liver Liver tissue No info Normal
A15 15 M 23 Liver Liver tissue No info Normal
A16 16 M 23 Liver Liver tissue No info Normal
B1 17 M 38 Liver Liver tissue No info Normal
B2 18 M 38 Liver Liver tissue No info Normal
B3 19 M 16 Liver Liver tissue No info Normal
B4 20 M 16 Liver Liver tissue No info Normal
B5 21 F 21 Liver Liver tissue No info Normal
B6 22 F 21 Liver Liver tissue No info Normal
B7 23 F 50 Liver Liver tissue No info Normal
B8 24 F 50 Liver Liver tissue No info Normal
B9 25 M 45 Liver Liver tissue No info Normal
B10 26 M 45 Liver Liver tissue No info Normal
B11 27 F 27 Liver Liver tissue No info Normal
B12 28 F 27 Liver Liver tissue No info Normal
B13 29 M 50 Liver Liver tissue No info Normal
B14 30 M 50 Liver Liver tissue (sparse) No info Normal
B15 31 M 35 Liver Liver tissue No info Normal
B16 32 M 35 Liver Liver tissue No info Normal
C1 33 M 49 Liver Chronic hepatitis Inflammation
C2 34 M 49 Liver Chronic hepatitis Inflammation
C3 35 M 67 Liver Chronic hepatitis Inflammation
C4 36 M 67 Liver Chronic hepatitis Inflammation
C5 37 M 55 Liver Chronic hepatitis Inflammation
C6 38 M 55 Liver Chronic hepatitis Inflammation
C7 39 F 55 Liver Chronic hepatitis Inflammation
C8 40 F 55 Liver Chronic hepatitis Inflammation
C9 41 M 52 Liver Chronic hepatitis Inflammation
C10 42 M 52 Liver Chronic hepatitis with fatty degeneration Inflammation
C11 43 M 72 Liver Chronic hepatitis Inflammation
C12 44 M 72 Liver Chronic hepatitis Inflammation
C13 45 F 58 Liver Chronic hepatitis Inflammation
C14 46 F 58 Liver Chronic hepatitis Inflammation
C15 47 F 48 Liver Chronic active hepatitis + Inflammation
C16 48 M 40 Liver Chronic hepatitis Inflammation
D1 49 M 40 Liver Chronic hepatitis Inflammation
D2 50 M 42 Liver Chronic hepatitis with fatty degeneration Inflammation
D3 51 M 42 Liver Chronic hepatitis with fatty degeneration Inflammation
D4 52 M 56 Liver Chronic hepatitis with fatty degeneration Inflammation
D5 53 M 56 Liver Chronic hepatitis with fatty degeneration Inflammation
D6 54 F 52 Liver Chronic hepatitis with fatty degeneration + Inflammation
D7 55 F 52 Liver Chronic hepatitis with fatty degeneration + Inflammation
D8 56 M 41 Liver Chronic hepatitis + Inflammation
D9 57 M 41 Liver Chronic hepatitis + Inflammation
D10 58 M 63 Liver Chronic hepatitis with fatty degeneration + Inflammation
D11 59 M 63 Liver Chronic hepatitis with fatty degeneration + Inflammation
D12 60 M 35 Liver Chronic hepatitis with fatty degeneration + Inflammation
D13 61 M 35 Liver Chronic hepatitis with fatty degeneration + Inflammation
D14 62 F 62 Liver Chronic active hepatitis with cholestasis + Inflammation
D15 63 F 62 Liver Chronic active hepatitis with cholestasis + Inflammation
D16 64 M 43 Liver Fatty degeneration + Inflammation
E1 65 M 43 Liver Fatty degeneration + Inflammation
E2 66 F 65 Liver Chronic active hepatitis with fatty degeneration + Inflammation
E3 67 F 65 Liver Chronic active hepatitis with fatty degeneration + Inflammation
E4 68 M 50 Liver Chronic active hepatitis with fatty degeneration + Inflammation
E5 69 M 50 Liver Chronic active hepatitis with fatty degeneration + Inflammation
E6 70 M 69 Liver Chronic hepatitis + Inflammation
E7 71 M 69 Liver Chronic hepatitis + Inflammation
E8 72 M 58 Liver Chronic active hepatitis with fatty degeneration + Inflammation
E9 73 M 58 Liver Chronic active hepatitis with fatty degeneration + Inflammation
E10 74 M 50 Liver Chronic active hepatitis with fatty degeneration + Inflammation
E11 75 M 50 Liver Chronic active hepatitis with fatty degeneration + Inflammation
E12 76 F 48 Liver Chronic active hepatitis + Inflammation
E13 77 M 56 Liver Chronic active hepatitis + Inflammation
E14 78 M 56 Liver Chronic active hepatitis + Inflammation
E15 79 F 56 Liver Chronic active hepatitis with fatty degeneration + Inflammation
E16 80 F 56 Liver Chronic active hepatitis with fatty degeneration + Inflammation
F1 81 F 50 Liver Nodular cirrhosis Cirrhosis
F2 82 F 50 Liver Nodular cirrhosis Cirrhosis
F3 83 F 43 Liver Nodular cirrhosis Cirrhosis
F4 84 F 43 Liver Nodular cirrhosis Cirrhosis
F5 85 F 36 Liver Nodular cirrhosis Cirrhosis
F6 86 F 36 Liver Nodular cirrhosis Cirrhosis
F7 87 M 54 Liver Nodular cirrhosis Cirrhosis
F8 88 M 54 Liver Nodular cirrhosis Cirrhosis
F9 89 M 45 Liver Nodular cirrhosis Cirrhosis
F10 90 M 45 Liver Nodular cirrhosis Cirrhosis
F11 91 M 57 Liver Nodular cirrhosis Cirrhosis
F12 92 M 57 Liver Nodular cirrhosis Cirrhosis
F13 93 M 62 Liver Nodular cirrhosis Cirrhosis
F14 94 M 62 Liver Nodular cirrhosis Cirrhosis
F15 95 M 46 Liver Nodular cirrhosis Cirrhosis
F16 96 M 46 Liver Nodular cirrhosis Cirrhosis
G1 97 F 47 Liver Nodular cirrhosis Cirrhosis
G2 98 F 47 Liver Nodular cirrhosis Cirrhosis
G3 99 M 49 Liver Nodular cirrhosis Cirrhosis
G4 100 M 49 Liver Nodular cirrhosis Cirrhosis
G5 101 M 40 Liver Nodular cirrhosis Cirrhosis
G6 102 M 40 Liver Nodular cirrhosis Cirrhosis
G7 103 M 46 Liver Nodular cirrhosis Cirrhosis
G8 104 M 46 Liver Nodular cirrhosis Cirrhosis
G9 105 M 25 Liver Nodular cirrhosis with bile duct proliferation Cirrhosis
G10 106 M 25 Liver Nodular cirrhosis Cirrhosis
G11 107 M 59 Liver Nodular cirrhosis Cirrhosis
G12 108 M 59 Liver Nodular cirrhosis Cirrhosis
G13 109 M 53 Liver Nodular cirrhosis Cirrhosis
G14 110 M 53 Liver Nodular cirrhosis Cirrhosis
G15 111 M 54 Liver Nodular cirrhosis Cirrhosis
G16 112 M 54 Liver Nodular cirrhosis Cirrhosis
H1 113 F 46 Liver Nodular cirrhosis + Cirrhosis
H2 114 F 46 Liver Nodular cirrhosis + Cirrhosis
H3 115 M 37 Liver Nodular cirrhosis + Cirrhosis
H4 116 M 37 Liver Nodular cirrhosis + Cirrhosis
H5 117 F 58 Liver Nodular cirrhosis + Cirrhosis
H6 118 F 58 Liver Nodular cirrhosis + Cirrhosis
H7 119 M 70 Liver Nodular cirrhosis + Cirrhosis
H8 120 M 70 Liver Nodular cirrhosis + Cirrhosis
H9 121 M 38 Liver Nodular cirrhosis + Cirrhosis
H10 122 M 38 Liver Nodular cirrhosis + Cirrhosis
H11 123 M 42 Liver Nodular cirrhosis + Cirrhosis
H12 124 M 42 Liver Nodular cirrhosis + Cirrhosis
H13 125 M 43 Liver Nodular cirrhosis with bile duct proliferation + Cirrhosis
H14 126 M 43 Liver Nodular cirrhosis + Cirrhosis
H15 127 M 60 Liver Nodular cirrhosis + Cirrhosis
H16 128 M 60 Liver Nodular cirrhosis + Cirrhosis
I1 129 M 55 Liver Nodular cirrhosis + Cirrhosis
I2 130 M 55 Liver Nodular cirrhosis + Cirrhosis
I3 131 M 33 Liver Nodular cirrhosis + Cirrhosis
I4 132 M 33 Liver Nodular cirrhosis + Cirrhosis
I5 133 M 52 Liver Nodular cirrhosis + Cirrhosis
I6 134 M 52 Liver Nodular cirrhosis + Cirrhosis
I7 135 M 24 Liver Nodular cirrhosis + Cirrhosis
I8 136 M 24 Liver Nodular cirrhosis with bile duct proliferation + Cirrhosis
I9 137 M 28 Liver Hepatocellular carcinoma 1 T3N0M0 Malignant
I10 138 M 28 Liver Hepatocellular carcinoma 1 T3N0M0 Malignant
I11 139 M 49 Liver Hepatocellular carcinoma 2 T2N0M0 Malignant
I12 140 M 49 Liver Hepatocellular carcinoma 2 T2N0M0 Malignant
I13 141 M 46 Liver Hepatocellular carcinoma 3 T2N0M0 Malignant
I14 142 M 46 Liver Hepatocellular carcinoma 3 T2N0M0 Malignant
I15 143 F 36 Liver Cholangiocellular carcinoma 3 T2N1M0 Malignant
I16 144 F 36 Liver Cholangiocellular carcinoma 3 T2N1M0 Malignant
J1 145 M 54 Liver Hepatocellular carcinoma 3 T2N1M0 Malignant
J2 146 M 54 Liver Hepatocellular carcinoma 3 T2N1M0 Malignant
J3 147 M 61 Liver Hepatocellular carcinoma 3 T3N0M0 Malignant
J4 148 M 61 Liver Hepatocellular carcinoma 3 T3N0M0 Malignant
J5 149 M 55 Liver Hepatocellular carcinoma 3 T1N0M0 Malignant
J6 150 M 55 Liver Hepatocellular carcinoma 3 T1N0M0 Malignant
J7 151 M 46 Liver Hepatocellular carcinoma 3 T3N0M0 Malignant
J8 152 M 46 Liver Hepatocellular carcinoma 3 T3N0M0 Malignant
J9 153 F 48 Liver Hepatocellular carcinoma 3 T3N0M0 Malignant
J10 154 F 48 Liver Hepatocellular carcinoma 3 T3N0M0 Malignant
J11 155 F 47 Liver Hepatocellular carcinoma 3 T2N0M0 Malignant
J12 156 F 47 Liver Hepatocellular carcinoma 3 T2N0M0 Malignant
J13 157 F 50 Liver Hepatocellular carcinoma 3 T2N0M0 Malignant
J14 158 F 50 Liver Hepatocellular carcinoma 3 T2N0M0 Malignant
J15 159 M 48 Liver Hepatocellular carcinoma 3 T3N0M0 Malignant
J16 160 M 48 Liver Hepatocellular carcinoma 3 T3N0M0 Malignant
K1 161 M 46 Liver Hepatocellular carcinoma 3 T3N0M0 Malignant
K2 162 M 46 Liver Hepatocellular carcinoma 3 T3N0M0 Malignant
K3 163 F 43 Liver Hepatocellular carcinoma 3 T2N0M0 Malignant
K4 164 F 43 Liver Hepatocellular carcinoma 3 T2N0M0 Malignant
K5 165 M 66 Liver Hepatocellular carcinoma 1 T2N0M0 + Malignant
K6 166 M 66 Liver Hepatocellular carcinoma 1 T2N0M0 + Malignant
K7 167 M 24 Liver Hepatocellular carcinoma 1 T2N0M0 + Malignant
K8 168 M 24 Liver Hepatocellular carcinoma 1 T2N0M0 + Malignant
K9 169 M 55 Liver Hepatocellular carcinoma 2 T2N0M0 + Malignant
K10 170 M 55 Liver Hepatocellular carcinoma 2 T2N0M0 + Malignant
K11 171 M 70 Liver Hepatocellular carcinoma 3 T3N0M0 + Malignant
K12 172 M 70 Liver Hepatocellular carcinoma 3 T3N0M0 + Malignant
K13 173 M 52 Liver Hepatocellular carcinoma 3 T3N0M0 + Malignant
K14 174 M 52 Liver Hepatocellular carcinoma 3 T3N0M0 + Malignant
K15 175 F 58 Liver Hepatocellular carcinoma 3 T2N0M0 + Malignant
K16 176 F 58 Liver Hepatocellular carcinoma 3 T2N0M0 + Malignant
L1 177 M 63 Liver Hepatocellular carcinoma 3 T3N0M0 + Malignant
L2 178 M 63 Liver Hepatocellular carcinoma 3 T2N0M0 + Malignant
L3 179 M 66 Liver Hepatocellular carcinoma 2 T2N0M0 + Malignant
L4 180 M 66 Liver Hepatocellular carcinoma 2 T2N0M0 + Malignant
L5 181 M 33 Liver Hepatocellular carcinoma 2 T2N0M0 + Malignant
L6 182 M 33 Liver Hepatocellular carcinoma 2 T2N0M0 + Malignant
L7 183 M 38 Liver Hepatocellular carcinoma 3 T3N0M0 + Malignant
L8 184 M 38 Liver Hepatocellular carcinoma 3 T3N0M0 + Malignant
L9 185 M 37 Liver Hepatocellular carcinoma 3 T3N0M0 + Malignant
L10 186 M 37 Liver Hepatocellular carcinoma 3 T3N0M0 + Malignant
L11 187 M 62 Liver Hepatocellular carcinoma 3 T3N0M0 + Malignant
L12 188 M 62 Liver Hepatocellular carcinoma 3 T3N0M0 + Malignant
L13 189 M 58 Liver Hepatocellular carcinoma T3N0M0 + Malignant
L14 190 M 58 Liver Hepatocellular carcinoma 3 T3N0M0 + Malignant
L15 191 M 40 Liver Hepatocellular carcinoma 3 T2N0M0 + Malignant
L16 192 M 40 Liver Hepatocellular carcinoma (sparse) 3 T2N0M0 + Malignant
M 42 Adrenal gland Pheochromocytoma (tissue marker) Malignant

† For precise diagnosis, refer to pathology description.

**The grade 1-3 (or I-III) in Pathology Diagnosis is equivalent to well-differentiated, moderately-differentiated or poorly differentiated, respectively, under microscope.
Grade 1 or well-differentiated: Cells appear normal and are not growing rapidly.
Grade 2 or moderately-differentiated: Cells appear slightly different than normal.
Grade 3 or poorly differentiated: Cells appear abnormal and tend to grow and spread more aggressively.
Grade 4 or undifferentiated: *(for certain tumors), features are not significantly distinguishing to make it look any different from undifferentiated cancers which occur in other organs.

Staining Scoring: "-" - no staining; "+-" - borderline staining; "+" - weak staining; "++" - moderate staining; "+++" - strong staining; "%" - percentage of positive cells.

TNM grading:

T - Primary tumor
Tx - Primary tumor cannot be assessed
T0 - No evidence of primary tumor
Tis - Carcinoma in situ; intraepithelial or invasion of lamina propria
T1 - Tumor invades submucosa
T2 - Tumor invades muscularis propria
T3 - Tumor invades through muscularis propria into subserosa or into non-peritonealized pericolic or perirectal tissues.
T4 - Tumor directly invades other organs or structures and/or perforate visceral peritoneum

N - Regional lymph nodes
Nx - Regional lymph nodes cannot be assessed
N0 - No regional lymph node metastasis
N1 - Metastasis in 1 to 3 regional lymph nodes
N2 - Metastasis in 4 or more regional lymph nodes

M - Distant metastasis
Mx - Distant metastasis cannot be assessed
M0 - No distant metastasis
M1 - Distant metastasis


Find overlapping cases with this tissue array: