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FDA902b
FDA Standard Frozen Tissue Array (2 slide set), for therapeutic and diagnostic monoclonal antibody validation recommanded by FDA, 90 tissue cores of 30 organs, 3 individual donors per organ, replacing tissue arrays
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FDA902b-1
FDA Standard Frozen Tissue Array, for therapeutic and diagnostic antibody validation for FDA approval, 45 cases/45 cores, slide 1 of 2 tissue arrays
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| Microarray Panel: | FDA Standard Frozen Tissue Microarray, containing 15 types of normal organs (lymph node, skeletal muscle, prostate, kidney, liver, lung, stomach, esophagus, heart, colon, small intestine, peripheral nerve, uterus, cerebellum and cerebrum), each organ taken from 3 normal human individuals, single core per case |
| Cores: | 45 |
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| Cases: | 45 |
| Layout: | 9 cols × 5 rows |
| Core Diameter: | 2 mm |
| Thickness: | 5 µm | | Quality Control: | Anti-Actin confirmed | | Applications: | Routine histology procedures including ImmunoHistochemistry (IHC) and In Situ Hybridization (ISH), protocols which can be found on our support page. |
| Notes: | Tissues were snap frozen in liquid nitrogen immediately after excision and were embedded in OCT. The array sections are 5-8 µm in thickness, mounted on positively charged glass slides, and briefly fixed by cold acetone. |
Microarray Panel Display | Legend: | Cer - Cerebrum,
Col - Colon,
Eso - Esophagus,
Hea - Heart,
Kid - Kidney,
Liv - Liver,
Lun - Lung,
Lym - Lymph node,
Per - Peripheral nerve,
Pro - Prostate,
Ske - Skeletal muscle,
Sma - Small intestine,
Smo - Smooth muscle,
Spi - Spinal cord,
Sto - Stomach
- Normal tissue
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Specification Sheet
| Pos |
No. |
Sex |
Age |
Organ |
Pathology diagnosis |
Type † |
|
A1 |
1 |
M |
28 |
Lymph node |
Normal lymph node tissue |
Normal |
|
A2 |
2 |
M |
42 |
Lymph node |
Normal lymph node tissue (fibrofatty tissue) |
Normal |
|
A3 |
3 |
M |
45 |
Lymph node |
Normal lymph node tissue |
Normal |
|
A4 |
4 |
M |
32 |
Skeletal muscle |
Normal skeletal muscle tissue |
Normal |
|
A5 |
5 |
M |
35 |
Skeletal muscle |
Normal skeletal muscle tissue |
Normal |
|
A6 |
6 |
M |
40 |
Skeletal muscle |
Normal skeletal muscle tissue |
Normal |
|
A7 |
7 |
M |
28 |
Prostate |
Normal prostate tissue |
Normal |
|
A8 |
8 |
M |
38 |
Prostate |
Normal prostate tissue |
Normal |
|
A9 |
9 |
M |
42 |
Prostate |
Normal prostate tissue |
Normal |
|
B1 |
10 |
M |
35 |
Kidney |
Normal kidney tissue (partial autolysis of renal tubule) |
Normal |
|
B2 |
11 |
M |
40 |
Kidney |
Normal kidney tissue (partial autolysis of renal tubule) |
Normal |
|
B3 |
12 |
M |
32 |
Kidney |
Normal kidney tissue (partial autolysis of renal tubule) |
Normal |
|
B4 |
13 |
M |
46 |
Liver |
Normal liver tissue |
Normal |
|
B5 |
14 |
M |
54 |
Liver |
Normal liver tissue |
Normal |
|
B6 |
15 |
M |
57 |
Liver |
Normal liver tissue |
Normal |
|
B7 |
16 |
M |
40 |
Lung |
Normal lung tissue |
Normal |
|
B8 |
17 |
M |
21 |
Lung |
Normal lung tissue |
Normal |
|
B9 |
18 |
M |
30 |
Lung |
Normal lung tissue |
Normal |
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C1 |
19 |
M |
30 |
Stomach |
Normal stomach tissue (smooth muscle) |
Normal |
|
C2 |
20 |
M |
31 |
Stomach |
Normal stomach tissue |
Normal |
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C3 |
21 |
M |
38 |
Stomach |
Normal stomach tissue |
Normal |
|
C4 |
22 |
M |
35 |
Esophagus |
Normal esophagus tissue (skeletal muscle and smooth muscle) |
Normal |
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C5 |
23 |
M |
28 |
Esophagus |
Normal esophagus tissue (skeletal muscle and smooth muscle) |
Normal |
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C6 |
24 |
M |
25 |
Esophagus |
Normal esophagus tissue |
Normal |
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C7 |
25 |
M |
21 |
Heart |
Normal cardiac muscle tissue |
Normal |
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C8 |
26 |
M |
24 |
Heart |
Normal cardiac muscle tissue |
Normal |
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C9 |
27 |
M |
28 |
Heart |
Normal cardiac muscle tissue |
Normal |
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D1 |
28 |
M |
40 |
Colon |
Normal colon tissue |
Normal |
|
D2 |
29 |
M |
42 |
Colon |
Normal colon tissue |
Normal |
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D3 |
30 |
M |
45 |
Colon |
Normal colon tissue |
Normal |
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D4 |
31 |
M |
28 |
Small intestine |
Normal small intestine tissue (smooth muscle) |
Normal |
|
D5 |
32 |
M |
40 |
Small intestine |
Normal small intestine tissue |
Normal |
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D6 |
33 |
M |
42 |
Small intestine |
Normal small intestine tissue (smooth muscle) |
Normal |
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D7 |
34 |
M |
28 |
Peripheral nerve |
Normal peripheral nerve tissue |
Normal |
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D8 |
35 |
M |
30 |
Peripheral nerve |
Normal peripheral nerve tissue |
Normal |
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D9 |
36 |
M |
42 |
Peripheral nerve |
Normal peripheral nerve tissue |
Normal |
|
E1 |
37 |
M |
40 |
Smooth muscle |
Normal smooth muscle tissue |
Normal |
|
E2 |
38 |
M |
35 |
Smooth muscle |
Normal smooth muscle tissue |
Normal |
|
E3 |
39 |
M |
30 |
Smooth muscle |
Normal smooth muscle and gland tissue |
Normal |
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E4 |
40 |
M |
45 |
Cerebellum |
Normal cerebellum tissue (partial autolysis) |
Normal |
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E5 |
41 |
M |
40 |
Cerebellum |
Normal cerebellum tissue |
Normal |
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E6 |
42 |
M |
35 |
Cerebellum |
Normal cerebellum tissue (partial autolysis) |
Normal |
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E7 |
43 |
M |
42 |
Cerebrum |
Normal cerebrum tissue |
Normal |
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E8 |
44 |
M |
40 |
Cerebrum |
Normal cerebrum tissue (partial autolysis) |
Normal |
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E9 |
45 |
M |
35 |
Spinal cord |
Spinal cord tissue |
Normal |
† For precise diagnosis, refer to pathology description.
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FDA902b-2
FDA Standard Frozen Tissue Array, for therapeutic and diagnostic antibody validation for FDA approval, 45 cases/45 cores, slide 2 of 2 tissue arrays, replacing FDA902-2
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| Microarray Panel: | FDA Standard Frozen Tissue Microarray, containing 15 types of normal organs (ovary, pancreas, salivary gland, pituitary gland, placenta, prostate, skin, spinal cord, spleen, skeletal muscle, testis, thymus, thyroid gland, ureter, uterine cervix), each organ taken from 3 normal human individuals, single core per case |
| Cores: | 45 |
|
| Cases: | 45 |
| Layout: | 9 cols × 5 rows |
| Core Diameter: | 2 mm |
| Thickness: | 5 µm | | Quality Control: | Anti-Actin confirmed | | Applications: | Routine histology procedures including ImmunoHistochemistry (IHC) and In Situ Hybridization (ISH), protocols which can be found on our support page. |
| Notes: | Tissues were snap frozen in liquid nitrogen immediately after excision and were embedded in OCT. The array sections are 5-8 µm in thickness, mounted on positively charged glass slides, and briefly fixed by cold acetone. |
*Tissue Microarray Slide Types:
- Unstained: unstained
frozen
tissue microarray slide.
- Trial: tissue microarray trial slide. 10% - 25% of cores missing. Good for titrating antibody dilution and experiment conditions. Limited numbers are available, to 2 per item per order. Test slides (tissue arrays with catalog numbers ending with 241 or 242) are recommended as a substitute.
- H & E: Hematoxylin and Eosin stained tissue microarray slide.
Microarray Panel Display | Legend: | Ova - Ovary,
Pan - Pancreas,
Pit - Pituitary gland,
Pla - Placenta,
Pro - Prostate,
Sal - Salivary gland,
Ske - Skeletal muscle,
Ski - Skin,
Spi - Spinal cord,
Spl - Spleen,
Tes - Testis,
Thy - Thyroid gland,
Ure - Ureter,
Ute - Uterine cervix
- Normal tissue
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Specification Sheet
| Pos |
No. |
Sex |
Age |
Organ |
Pathology diagnosis |
Type † |
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A1 |
1 |
F |
51 |
Ovary |
Normal ovary tissue |
Normal |
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A2 |
2 |
F |
52 |
Ovary |
Normal ovary tissue |
Normal |
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A3 |
3 |
F |
56 |
Ovary |
Normal ovary tissue |
Normal |
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A4 |
4 |
M |
25 |
Pancreas |
Normal pancreas tissue |
Normal |
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A5 |
5 |
M |
40 |
Pancreas |
Normal pancreas tissue |
Normal |
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A6 |
6 |
M |
40 |
Pancreas |
Normal pancreas tissue |
Normal |
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A7 |
7 |
M |
40 |
Salivary gland |
Normal salivary gland tissue |
Normal |
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A8 |
8 |
M |
35 |
Salivary gland |
Normal salivary gland tissue |
Normal |
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A9 |
9 |
M |
42 |
Salivary gland |
Normal salivary gland tissue (fatty tissue and blood vessel) |
Normal |
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B1 |
10 |
M |
42 |
Pituitary gland |
Normal pituitary gland tissue (autolysis) |
Normal |
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B2 |
11 |
M |
42 |
Pituitary gland |
Normal pituitary gland tissue (autolysis) |
Normal |
|
B3 |
12 |
M |
42 |
Pituitary gland |
Normal pituitary gland tissue |
Normal |
|
B4 |
13 |
M |
5 Mon. |
Placenta |
Normal placenta tissue |
Normal |
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B5 |
14 |
M |
5 Mon. |
Placenta |
Normal placenta tissue |
Normal |
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B6 |
15 |
M |
5 Mon. |
Placenta |
Normal placenta tissue |
Normal |
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B7 |
16 |
M |
32 |
Prostate |
Normal prostate tissue |
Normal |
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B8 |
17 |
M |
25 |
Prostate |
Normal prostate tissue |
Normal |
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B9 |
18 |
M |
42 |
Prostate |
Normal prostate tissue |
Normal |
|
C1 |
19 |
M |
32 |
Skin |
Normal skin tissue |
Normal |
|
C2 |
20 |
M |
25 |
Skin |
Normal skin tissue |
Normal |
|
C3 |
21 |
M |
40 |
Skin |
Normal skin tissue |
Normal |
|
C4 |
22 |
M |
40 |
Spinal cord |
Normal spinal cord tissue |
Normal |
|
C5 |
23 |
M |
40 |
Spinal cord |
Normal spinal cord tissue |
Normal |
|
C6 |
24 |
M |
42 |
Spinal cord |
Normal spinal cord tissue |
Normal |
|
C7 |
25 |
M |
48 |
Spleen |
Normal spleen tissue |
Normal |
|
C8 |
26 |
F |
40 |
Spleen |
Normal spleen tissue |
Normal |
|
C9 |
27 |
M |
25 |
Spleen |
Normal spleen tissue |
Normal |
|
D1 |
28 |
M |
30 |
Skeletal muscle |
Normal skeletal muscle tissue |
Normal |
|
D2 |
29 |
M |
25 |
Skeletal muscle |
Normal skeletal muscle tissue |
Normal |
|
D3 |
30 |
F |
23 |
Skeletal muscle |
Normal skeletal muscle tissue |
Normal |
|
D4 |
31 |
M |
36 |
Testis |
Normal testis tissue |
Normal |
|
D5 |
32 |
M |
28 |
Testis |
Normal testis tissue |
Normal |
|
D6 |
33 |
M |
32 |
Testis |
Normal testis tissue |
Normal |
|
D7 |
34 |
M |
35 |
Thymus |
Normal thymus tissue |
Normal |
|
D8 |
35 |
M |
31 |
Thymus |
Normal thymus tissue |
Normal |
|
D9 |
36 |
M |
35 |
Thymus |
Normal thymus tissue |
Normal |
|
E1 |
37 |
F |
37 |
Thyroid gland |
Normal thyroid gland tissue |
Normal |
|
E2 |
38 |
M |
31 |
Thyroid gland |
Normal thyroid gland tissue |
Normal |
|
E3 |
39 |
M |
40 |
Thyroid gland |
Normal thyroid gland tissue |
Normal |
|
E4 |
40 |
M |
38 |
Ureter |
Normal ureter tissue |
Normal |
|
E5 |
41 |
M |
38 |
Ureter |
Normal ureter tissue |
Normal |
|
E6 |
42 |
M |
38 |
Ureter |
Normal ureter tissue |
Normal |
|
E7 |
43 |
F |
47 |
Uterine cervix |
Normal cervix tissue (fibrous tissue and blood vessel) |
Normal |
|
E8 |
44 |
F |
47 |
Uterine cervix |
Normal cervix tissue |
Normal |
|
E9 |
45 |
F |
45 |
Uterine cervix |
Normal cervix tissue |
Normal |
† For precise diagnosis, refer to pathology description.
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