US Biomax, Inc.

FBN406e

Frozen multiple organ normal tissue array, 20 organs/40 cores, replacing FBN406d

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Microarray Panel:Frozen multiple organ normal tissue microarray, containing 20 types of normal organs (cerebrum, medulla oblongata, esophagus, stomach, small intestine, colon, spleen, thymus, lung, pancreas, adrenal gland, kidney, breast, ovary, prostate, testis, skin, smooth muscle, skeletal muscle and placenta), each organ taken from 1 normal human individuals, duplicate cores per case
Cores:40
Cases:20
Layout:8 cols × 5 rows
Core Diameter:2 mm
Thickness:5 µm
Quality Control:H&E and IHC confirmed
Applications:

Routine histology procedures including Immunohistochemistry (IHC) and In Situ Hybridization (ISH), protocols which can be found at our support page.

Notes:Tissues were snap frozen in liquid nitrogen immediately after excision and were embedded in OCT. The array sections are 5-8 µm in thickness, mounted on positively charged glass slides, and briefly fixed by cold acetone.


Microarray Panel Display

 
Slide Label: US Biomax, Inc. Tissue Array
12345678
A Cer Cer Med Med Eso Eso Sto Sto
B Sma Sma Col Col Spl Spl Thy Thy
C Lun Lun Pan Pan Adr Adr Kid Kid
D Bre Bre Ova Ova Pro Pro Tes Tes
E Ski Ski Smo Smo Ske Ske Pla Pla
Legend: Adr - Adrenal gland, Bre - Breast, Cer - Cerebrum, Col - Colon, Eso - Esophagus, Kid - Kidney, Lun - Lung, Med - Medulla oblongata, Ova - Ovary, Pan - Pancreas, Pla - Placenta, Pro - Prostate, Ske - Skeletal muscle, Ski - Skin, Sma - Small intestine, Smo - Smooth muscle, Spl - Spleen, Sto - Stomach, Tes - Testis, Thy - Thymus

- Normal tissue

Specification Sheet

Pos No. Sex Age Organ Pathology diagnosis Type †
A1 1 M 28 Cerebrum Cerebrum tissue Normal
A2 2 M 28 Cerebrum Cerebrum tissue Normal
A3 3 M 42 Medulla oblongata Medulla oblongata tissue Normal
A4 4 M 42 Medulla oblongata Medulla oblongata tissue Normal
A5 5 M 28 Esophagus Esophagus tissue Normal
A6 6 M 28 Esophagus Esophagus tissue Normal
A7 7 F 27 Stomach Stomach tissue Normal
A8 8 F 27 Stomach Stomach tissue Normal
B1 9 M 35 Small intestine Small intestine tissue Normal
B2 10 M 35 Small intestine Small intestine tissue Normal
B3 11 M 28 Colon Colon tissue Normal
B4 12 M 28 Colon Colon tissue Normal
B5 13 M 47 Spleen Spleen tissue Normal
B6 14 M 47 Spleen Spleen tissue Normal
B7 15 M 28 Thymus Thymus tissue Normal
B8 16 M 28 Thymus Thymus tissue Normal
C1 17 M 38 Lung Lung tissue Normal
C2 18 M 38 Lung Lung tissue Normal
C3 19 M 40 Pancreas Pancreas tissue Normal
C4 20 M 40 Pancreas Pancreas tissue Normal
C5 21 M 35 Adrenal gland Adrenal gland tissue Normal
C6 22 M 35 Adrenal gland Adrenal gland tissue Normal
C7 23 M 28 Kidney Kidney tissue Normal
C8 24 M 28 Kidney Kidney tissue Normal
D1 25 F 27 Breast Breast tissue Normal
D2 26 F 27 Breast Breast tissue Normal
D3 27 F 27 Ovary Ovary tissue Normal
D4 28 F 27 Ovary Ovary tissue Normal
D5 29 M 25 Prostate Prostate tissue Normal
D6 30 M 25 Prostate Prostate tissue Normal
D7 31 M 38 Testis Testis tissue Normal
D8 32 M 38 Testis Testis tissue Normal
E1 33 M 21 Skin Skin tissue Normal
E2 34 M 21 Skin Skin tissue Normal
E3 35 F 36 Smooth muscle Smooth muscle tissue Normal
E4 36 F 36 Smooth muscle Smooth muscle tissue Normal
E5 37 M 38 Skeletal muscle Skeletal muscle tissue Normal
E6 38 M 38 Skeletal muscle Skeletal muscle tissue Normal
E7 39 F 7 Mon. Placenta Placenta tissue Normal
E8 40 F 7 Mon. Placenta Placenta tissue Normal

† For precise diagnosis, refer to pathology description.

TNM Grading

Primary tumor (T)

  • TX: Primary tumor cannot be assessed
  • T0: No evidence of primary tumor
  • Tis: Intraductal carcinoma, lobular carcinoma in situ, or Paget's disease of the nipple with no associated invasion of normal breast tissue
    • Tis (DCIS): Ductal carcinoma in situ
    • Tis (LCIS): Lobular carcinoma in situ
    • Tis (Paget's): Paget's disease of the nipple with no tumor. [Note: Paget's disease associated with a tumor is classified according to the size of the tumor.]
  • T1: Tumor 2.0 cm or less in greatest dimension
    • T1mic: Microinvasion 0.1 cm or less in greatest dimension
    • T1a: Tumor more than 0.1 but not more than 0.5 cm in greatest dimension
    • T1b: Tumor more than 0.5 cm but not more than 1.0 cm in greatest dimension
    • T1c: Tumor more than 1.0 cm but not more than 2.0 cm in greatest dimension
  • T2: Tumor more than 2.0 cm but not more than 5.0 cm in greatest dimension
  • T3: Tumor more than 5.0 cm in greatest dimension
  • T4: Tumor of any size with direct extension to (a) chest wall or (b) skin, only as described below.
    • T4a: Extension to chest wall, not including pectoralis muscle
    • T4b: Edema (including peau d'orange) or ulceration of the skin of the breast, or satellite skin nodules confined to the same breast
    • T4c: Both T4a and T4b
    • T4d: Inflammatory carcinoma.
  • Memory Aid for Primary tumor: The two numbers to remember are 2.0 and 5.0
    • T1 is no larger than 2.0 cm
    • T2 > 2.0 - 5.0 cm
    • T3 > 5.0 cm

Regional lymph nodes (N)

  • NX: Regional lymph nodes cannot be assessed (e.g., previously removed)
  • N0: No regional lymph node metastasis
  • N1: Metastasis to movable ipsilateral axillary lymph node(s)
  • N2: Metastasis to ipsilateral axillary lymph node(s) fixed or matted, or in clinically apparent* ipsilateral internal mammary notes in the absence of clinically evident lymph node metastasis
    • N2a: Metastasis in ipsilateral axillary lymph nodes fixed to one another (matted) or to other structures
    • N2b: Metastasis only in clinically apparent* ipsilateral internal mammary nodes and in the absence of clinically evident axillary lymph node metastasis.
  • N3: Metastasis in ipsilateral infraclavicular lymph node(s) with or without axillary lymph node involvement, or in clinically apparent* ipsilateral internal mammary lymph node(s) and in the presence of clinically evident axillary lymph node metastasis; or metastasis in ipsilateral supraclavicular lymph node(s) with or without axillary or internal mammary lymph node involvement
    • N3a: Metastasis in ipsilateral infraclavicular lymph node(s)
    • N3b: Metastasis in ipsilateral internal mammary lymph node(s) and axillary lymph node(s)
    • N3c: Metastasis in ipsilateral supraclavicular lymph node(s)

* [Note: Clinically apparent is defined as detected by imaging studies (excluding lymphoscintigraphy) or by clinical examination or grossly visible pathologically.]

Distant metastasis (M)

  • MX: Presence of distant metastasis cannot be assessed
  • M0: No distant metastasis
  • M1: Distant metastasis

Find overlapping cases with this tissue array: