US Biomax, Inc.

T053b

Colon tumor test tissue array, with normal colon tissue as control, including TNM, clinical stage and pathology grade, 2 serial sections, 6 cases/12 cores, replaced by T053c

Microarray Panel:Colon tumor test tissue microarray, containing 4 cases of malignant tumor (1 each of mucinous adenocarcinoma, papillary adenocarcinoma, carcinoid tumour and signet-ring cell carcinoma), 2 normal tissue, quadruple cores per case, 2 serial sections, divided into two identical 12 core arrays for testing different antibody dilutions
Cores:24
Cases:6
Layout:8 cols × 3 rows
Core Diameter:1.5 mm
Thickness:5 µm
Quality Control:H&E and IHC confirmed
Applications:

Routine histology procedures including Immunohistochemistry (IHC) and In Situ Hybridization (ISH), protocols which can be found at our support page.

Notes:1. TMA slides were sectioned and stored at 4°C and may not be fresh cut, but still suitable for IHC. Please request fresh cut if experiment involves phospho-specific antibodies, RNA studies, FISH or ISH, etc. A minimum of 3 slides per TMA must be purchased to cover the cost of trimming for fresh sectioning.
2. Most of the TMA slides were not coated with an extra layer of paraffin (tissue cores can be easily seen on the glass). We still recommend 30 minutes of baking at 60°C before putting into xylene for de-paraffinization procedure.


Microarray Panel Display

 
Slide Label: US Biomax, Inc. Tissue Array
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A Col Col Col Col Col Col Col Col  
B Col Col Col Col Col Col Col Col  
C Col Col Col Col Col Col Col Col Marked point
Legend: Col - Colon

- Malignant tumor, - Malignant tumor (stage IIA), - Malignant tumor (stage III), - Normal tissue

Specification Sheet

Pos No. Sex Age Organ Pathology diagnosis Grade Stage TNM Type †
A1 1 M 48 Colon Mucinous adenocarcinoma 3 III T4N1M0 Malignant
A2 2 M 48 Colon Mucinous adenocarcinoma 3 III T4N1M0 Malignant
A3 3 F 60 Colon Papillary adenocarcinoma 1 III T3N1M0 Malignant
A4 4 F 60 Colon Papillary adenocarcinoma 1 III T3N1M0 Malignant
A5 5 M 48 Colon Mucinous adenocarcinoma with necrosis 3 III T4N1M0 Malignant
A6 6 M 48 Colon Mucinous adenocarcinoma with necrosis 3 III T4N1M0 Malignant
A7 7 F 60 Colon Papillary adenocarcinoma 1 III T3N1M0 Malignant
A8 8 F 60 Colon Papillary adenocarcinoma 1 III T3N1M0 Malignant
B1 9 M 52 Colon Carcinoid tumor IIA T3N0M0 Malignant
B2 10 M 52 Colon Carcinoid tumor IIA T3N0M0 Malignant
B3 11 F 47 Colon Signet-ring cell carcinoma III T3N1M0 Malignant
B4 12 F 47 Colon Signet-ring cell carcinoma III T3N1M0 Malignant
B5 13 M 52 Colon Carcinoid tumor IIA T3N0M0 Malignant
B6 14 M 52 Colon Carcinoid tumor IIA T3N0M0 Malignant
B7 15 F 47 Colon Signet-ring cell carcinoma III T3N1M0 Malignant
B8 16 F 47 Colon Signet-ring cell carcinoma III T3N1M0 Malignant
C1 17 M 30 Colon Colon tissue Normal
C2 18 M 30 Colon Colon tissue Normal
C3 19 M 31 Colon Colon tissue Normal
C4 20 M 31 Colon Colon tissue Normal
C5 21 M 30 Colon Colon tissue Normal
C6 22 M 30 Colon Colon tissue Normal
C7 23 M 31 Colon Colon tissue Normal
C8 24 M 31 Colon Colon tissue Normal
M 42 Adrenal gland Pheochromocytoma (tissue marker) Malignant

† For precise diagnosis, refer to pathology description.

**The grade 1-3 (or I-III) in Pathology Diagnosis is equivalent to well-differentiated, moderately-differentiated or poorly differentiated, respectively, under microscope.
Grade 1 or well-differentiated: Cells appear normal and are not growing rapidly.
Grade 2 or moderately-differentiated: Cells appear slightly different than normal.
Grade 3 or poorly differentiated: Cells appear abnormal and tend to grow and spread more aggressively.
Grade 4 or undifferentiated: *(for certain tumors), features are not significantly distinguishing to make it look any different from undifferentiated cancers which occur in other organs.

TNM grading:

T - Primary tumor
Tx - Primary tumor cannot be assessed
T0 - No evidence of primary tumor
Tis - Carcinoma in situ; intraepithelial or invasion of lamina propria
T1 - Tumor invades submucosa
T2 - Tumor invades muscularis propria
T3 - Tumor invades through muscularis propria into subserosa or into non-peritonealized pericolic or perirectal tissues.
T4 - Tumor directly invades other organs or structures and/or perforate visceral peritoneum

N - Regional lymph nodes
Nx - Regional lymph nodes cannot be assessed
N0 - No regional lymph node metastasis
N1 - Metastasis in 1 to 3 regional lymph nodes
N2 - Metastasis in 4 or more regional lymph nodes

M - Distant metastasis
Mx - Distant metastasis cannot be assessed
M0 - No distant metastasis
M1 - Distant metastasis


Find overlapping cases with this tissue array: