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CO951
Colon cancer tissue array with matched normal adjacent and metastatic carcinoma tissue, with TNM, clinical stage and survival data, 30 cases/95 cores, to be replaced by CO952
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| Microarray Panel: | Colon adenocarcinoma tissue microarray, duplicated cores, 30 cancer and 8 of which has matched normal adjacent tissue and 10 cases of matched metastasis, with follow-up data 2 cores per case |
| Cores: | 95 |
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| Cases: | 30 |
| Layout: | 12 cols × 8 rows |
| Core Diameter: | 1.5 mm |
| Thickness: | 5 µm |
| Quality Control: | Anti-Cytokeratin (CK) confirmed |
| Applications: | Routine histology procedures including ImmunoHistochemistry (IHC) and In Situ Hybridization (ISH), protocols which can be found on our support page. |
| Notes: | Unless specified, all TMA slides are not coated with extra layer of paraffin (tissue cores can be easily seen on the glass), so there is no need to bake, can be directly put into xylene for de-paraffin procedure. |
*Tissue Microarray Slide Types:
- Unstained: unstained
paraffin
tissue microarray slide.
- Trial: tissue microarray trial slide. 10% - 25% of cores missing. Good for titrating antibody dilution and experiment conditions. Limited numbers are available, to 2 per item per order. Test slides (tissue arrays with catalog numbers ending with 241 or 242) are recommended as a substitute.
- H & E: Hematoxylin and Eosin stained tissue microarray slide.
Microarray Panel Display  | | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 |
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| Legend: | Asc - Ascending colon,
Car - Carbon,
Cec - Cecum,
Des - Descending colon,
Lun - Lung,
Lym - Lymph node,
Ova - Ovary,
Rec - Rectum,
Sig - Sigmoid colon,
Tra - Transverse colon
- Carbon,
- Malignant tumor (stage IIA),
- Malignant tumor (stage IIIB),
- Malignant tumor (stage IIIC),
- Malignant tumor (stage IV),
- Metastasis,
- NAT
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Specification Sheet
| Pos |
No. |
Sex |
Age |
Organ |
Pathology diagnosis |
Stage |
pTNM |
Months |
Type † |
|
A1, A2 |
1 |
M |
62 |
Rectum |
Adenocarcinoma, moderately differentiated |
IIIB |
T4N1M1 |
. |
Malignant |
|
A3, A4 |
2 |
F |
40 |
Sigmoid colon |
Adenocarcinoma, well differentiated |
IIIC |
T3N2M0 |
. |
Malignant |
|
A5, A6 |
3 |
M |
56 |
Ascending colon |
Adenocarcinoma, moderately differentiated |
IIIB |
T3N1M0 |
. |
Malignant |
|
A7, A8 |
4 |
M |
36 |
Transverse colon |
Adenocarcinoma, moderately differentiated |
IIIC |
T3N2M1 |
. |
Malignant |
|
A9, A10 |
5 |
F |
65 |
Sigmoid colon |
Adenocarcinoma, well differentiated |
IIA |
T3N0M0 |
. |
Malignant |
|
A11, A12 |
6 |
M |
62 |
Ascending colon |
Adenocarcinoma, moderately differentiated |
IIA |
T3N0M0 |
. |
Malignant |
|
B1, B2 |
7 |
F |
57 |
Sigmoid colon |
Adenocarcinoma, well differentiated |
IIIB |
T3N1M0 |
. |
Malignant |
|
B3, B4 |
8 |
F |
– |
Descending colon |
Adenocarcinoma, well differentiated |
IV |
T4N1M1 |
. |
Malignant |
|
B5, B6 |
9 |
M |
45 |
Rectum |
Adenocarcinoma, well differentiated |
IIIB |
T3N1M0 |
. |
Malignant |
|
B7, B8 |
10 |
M |
65 |
Ascending colon |
Adenocarcinoma, well differentiated |
IIIB |
T3N1M0 |
. |
Malignant |
|
B9, B10 |
11 |
F |
63 |
Descending colon |
Adenocarcinoma, moderately differentiated |
IIIB |
T3N1M0 |
. |
Malignant |
|
B11, B12 |
12 |
M |
53 |
Cecum |
Adenocarcinoma, moderately differentiated |
IIIB |
T3N1M0 |
. |
Malignant |
|
C1, C2 |
13 |
M |
64 |
Sigmoid colon |
Adenocarcinoma, moderately differentiated |
IIIB |
T3N1M0 |
. |
Malignant |
|
C3, C4 |
14 |
F |
46 |
Ascending colon |
Adenocarcinoma, poorly differentiated |
IIIC |
T3N2M1 |
. |
Malignant |
|
C5, C6 |
15 |
M |
59 |
Ascending colon |
Adenocarcinoma, moderately differentiated |
IIA |
T3N0M0 |
. |
Malignant |
|
C7, C8 |
16 |
M |
42 |
Transverse colon |
Adenocarcinoma, moderately differentiated |
IIIC |
T3N2M1 |
. |
Malignant |
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C9, C10 |
17 |
F |
49 |
Ascending colon |
Adenocarcinoma, moderately differentiated |
IIIC |
T3N2M0 |
. |
Malignant |
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C11, C12 |
18 |
M |
76 |
Sigmoid colon |
Adenocarcinoma, moderately differentiated |
IV |
T3N1M1 |
. |
Malignant |
|
D1, D2 |
19 |
M |
74 |
Ascending colon |
Adenocarcinoma, moderately differentiated |
IIA |
T3N0M0 |
. |
Malignant |
|
D3, D4 |
20 |
M |
62 |
Sigmoid colon |
Adenocarcinoma, moderately differentiated |
IV |
T3N2M1 |
. |
Malignant |
|
D5, D6 |
21 |
M |
62 |
Sigmoid colon |
Adenocarcinoma, moderately differentiated |
IIA |
T3N0M0 |
. |
Malignant |
|
D7, D8 |
22 |
F |
56 |
Sigmoid colon |
Adenocarcinoma, moderately differentiated |
IV |
T3N2M1 |
. |
Malignant |
|
D9, D10 |
23 |
F |
75 |
Rectum |
Adenocarcinoma, well differentiated |
IIIB |
T3N1M0 |
. |
Malignant |
|
D11, D12 |
24 |
F |
41 |
Sigmoid colon |
Adenocarcinoma, well differentiated |
IV |
T4N2M1 |
. |
Malignant |
|
E1, E2 |
25 |
M |
51 |
Rectum |
Adenocarcinoma, moderately differentiated |
IIIC |
T4N2M1 |
. |
Malignant |
|
E3, E4 |
26 |
F |
47 |
Sigmoid colon |
Adenocarcinoma, moderately differentiated |
IV |
T4N1M1 |
. |
Malignant |
|
E5, E6 |
27 |
M |
68 |
Sigmoid colon |
Adenocarcinoma, moderately differentiated |
IIIB |
T3N1M0 |
. |
Malignant |
|
E7, E8 |
28 |
F |
65 |
Cecum |
Mucinous adenocarcinoma |
IIIC |
T3N2M1 |
. |
Malignant |
|
E9, E10 |
29 |
M |
61 |
Transverse colon |
Mucinous adenocarcinoma |
IIA |
T3N0M0 |
. |
Malignant |
|
E11, E12 |
30 |
F |
35 |
Ascending colon |
Mucinous adenocarcinoma |
IIA |
T3N0M0 |
. |
Malignant |
|
F1, F2 |
31 |
M |
66 |
Lung |
Metastatic adenocarcinoma from #1 |
. |
. |
42 |
Metastasis |
|
F3, F4 |
32 |
M |
36 |
Lymph node |
Metastatic carcinoma from #4 |
. |
. |
0 |
Metastasis |
|
F5, F6 |
33 |
F |
– |
Ovary |
Metastatic adenocarcinoma from #8 |
. |
. |
0 |
Metastasis |
|
F7, F8 |
34 |
F |
46 |
Lymph node |
Metastatic carcinoma from #14 |
. |
. |
0 |
Metastasis |
|
F9, F10 |
35 |
M |
42 |
Lymph node |
Metastatic carcinoma from #16 |
. |
. |
0 |
Metastasis |
|
F11, F12 |
36 |
M |
62 |
Lymph node |
Metastatic carcinoma from #20 |
. |
. |
0 |
Metastasis |
|
G1, G2 |
37 |
F |
41 |
Ovary |
Metastatic adenocarcinoma from #24 |
. |
. |
0 |
Metastasis |
|
G3, G4 |
38 |
M |
52 |
Lung |
Metastatic adenocarcinoma from #25 |
. |
. |
17 |
Metastasis |
|
G5, G6 |
39 |
F |
47 |
Ovary |
Metastatic adenocarcinoma from #26 |
. |
. |
0 |
Metastasis |
|
G7, G8 |
40 |
F |
65 |
Lymph node |
Metastatic carcinoma from #28 |
. |
. |
0 |
Metastasis |
|
G9, G10 |
41 |
F |
40 |
Sigmoid colon |
Normal colon (match of #2) |
. |
. |
. |
NAT |
|
G11, G12 |
42 |
M |
56 |
Ascending colon |
Normal colon (match of #3) |
. |
. |
. |
NAT |
|
H1, H2 |
43 |
M |
62 |
Ascending colon |
Normal colon (match of #6) |
. |
. |
. |
NAT |
|
H3, H4 |
44 |
M |
45 |
Rectum |
Normal colon (match of #9) |
. |
. |
. |
NAT |
|
H5, H6 |
45 |
F |
63 |
Descending colon |
Normal colon (match of #11) |
. |
. |
. |
NAT |
|
H7, H8 |
46 |
F |
49 |
Ascending colon |
Normal colon (match of #17) |
. |
. |
. |
NAT |
|
H9, H10 |
47 |
M |
76 |
Sigmoid colon |
Normal colon (match of #18) |
. |
. |
. |
NAT |
|
H11 |
48 |
M |
62 |
Sigmoid colon |
Normal colon (match of #21) |
. |
. |
. |
NAT |
**The grade 1-3 (or I-III) in Pathology Diagnosis is equivalent to well-differentiated, moderately-differentiated or poorly differentiated, respectively, under microscope.
Grade 1 or well-differentiated: Cells appear normal and are not growing rapidly.
Grade 2 or moderately-differentiated: Cells appear slightly different than normal.
Grade 3 or poorly differentiated: Cells appear abnormal and tend to grow and spread more aggressively.
Grade 4 or undifferentiated: *(for certain tumors), features are not significantly distinguishing to make it look any different from undifferentiated cancers which occur in other organs.
TNM grading:
T - Primary tumor
Tx - Primary tumor cannot be assessed
T0 - No evidence of primary tumor
Tis - Carcinoma in situ; intraepithelial or invasion of lamina propria
T1 - Tumor invades submucosa
T2 - Tumor invades muscularis propria
T3 - Tumor invades through muscularis propria into subserosa or into non-peritonealized pericolic or perirectal tissues.
T4 - Tumor directly invades other organs or structures and/or perforate visceral peritoneum
N - Regional lymph nodes
Nx - Regional lymph nodes cannot be assessed
N0 - No regional lymph node metastasis
N1 - Metastasis in 1 to 3 regional lymph nodes
N2 - Metastasis in 4 or more regional lymph nodes
M - Distant metastasis
Mx - Distant metastasis cannot be assessed
M0 - No distant metastasis
M1 - Distant metastasis
† For precise diagnosis, refer to pathology description.
Supplementary Data
| Pos |
No. |
Follow-up months |
Follow-up result |
Cause of death |
Remark |
| A1, A2 |
1 |
67 |
dead |
cancer |
. |
| A3, A4 |
2 |
130 |
alive |
. |
. |
| A5, A6 |
3 |
30 |
dead |
cancer |
. |
| A7, A8 |
4 |
2 |
dead |
cancer |
. |
| A9, A10 |
5 |
125 |
alive |
. |
. |
| A11, A12 |
6 |
125 |
alive |
. |
. |
| B1, B2 |
7 |
125 |
alive |
. |
. |
| B3, B4 |
8 |
0 |
lost |
. |
. |
| B5, B6 |
9 |
0 |
dead |
cancer |
. |
| B7, B8 |
10 |
124 |
alive |
. |
. |
| B9, B10 |
11 |
124 |
alive |
. |
. |
| B11, B12 |
12 |
123 |
alive |
. |
. |
| C1, C2 |
13 |
123 |
alive |
. |
. |
| C3, C4 |
14 |
2 |
dead |
cancer |
. |
| C5, C6 |
15 |
35 |
dead |
cancer |
. |
| C7, C8 |
16 |
122 |
alive |
. |
. |
| C9, C10 |
17 |
122 |
alive |
. |
. |
| C11, C12 |
18 |
57 |
dead |
cancer |
. |
| D1, D2 |
19 |
122 |
alive |
. |
. |
| D3, D4 |
20 |
3 |
dead |
cancer |
. |
| D5, D6 |
21 |
121 |
alive |
. |
. |
| D7, D8 |
22 |
11 |
dead |
cancer |
. |
| D9, D10 |
23 |
121 |
alive |
. |
. |
| D11, D12 |
24 |
12 |
dead |
cancer |
. |
| E1, E2 |
25 |
105 |
alive |
. |
. |
| E3, E4 |
26 |
25 |
dead |
cancer |
. |
| E5, E6 |
27 |
60 |
dead |
cancer |
. |
| E7, E8 |
28 |
127 |
alive |
. |
. |
| E9, E10 |
29 |
124 |
alive |
. |
. |
| E11, E12 |
30 |
122 |
alive |
. |
. |
| F1, F2 |
31 |
22 |
dead |
cancer |
. |
| F3, F4 |
32 |
2 |
dead |
cancer |
. |
| F5, F6 |
33 |
0 |
lost |
. |
. |
| F7, F8 |
34 |
2 |
dead |
cancer |
. |
| F9, F10 |
35 |
122 |
alive |
. |
. |
| F11, F12 |
36 |
3 |
dead |
cancer |
. |
| G1, G2 |
37 |
12 |
dead |
cancer |
. |
| G3, G4 |
38 |
88 |
alive |
. |
. |
| G5, G6 |
39 |
25 |
dead |
cancer |
. |
| G7, G8 |
40 |
127 |
alive |
. |
. |
| G9, G10 |
41 |
. |
. |
. |
. |
| G11, G12 |
42 |
. |
. |
. |
. |
| H1, H2 |
43 |
. |
. |
. |
. |
| H3, H4 |
44 |
. |
. |
. |
. |
| H5, H6 |
45 |
. |
. |
. |
. |
| H7, H8 |
46 |
. |
. |
. |
. |
| H9, H10 |
47 |
. |
. |
. |
. |
| H11 |
48 |
. |
. |
. |
. |
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