Specification Sheet

Pos	No.	Sex	Age	Organ	Pathology diagnosis	Grade	Stage	TNM	ER	PR	Type †
A1	1	F	46	Breast	Mucinous carcinoma	2	IIa	T2N0M0	–	–	Malignant
A2	2	F	47	Breast	Mucinous carcinoma	2	IIb	T3N0M0	+, 70%	+, 35%	Malignant
A3	3	F	69	Breast	Medullary carcinoma	–	IIa	T2N0M0	+++, 100%	–	Malignant
A4	4	F	63	Breast	Medullary carcinoma	–	I	T1N0M0	++, 75%	+, 0.1%	Malignant
A5	5	F	46	Breast	Mucinous carcinoma	2	IIa	T2N0M0	–	–	Malignant
A6	6	F	47	Breast	Mucinous carcinoma	2	IIb	T3N0M0	+, 70%	+, 35%	Malignant
A7	7	F	69	Breast	Medullary carcinoma	–	IIa	T2N0M0	+++, 100%	–	Malignant
A8	8	F	63	Breast	Medullary carcinoma	–	I	T1N0M0	++, 75%	+, 0.1%	Malignant
B1	9	F	50	Breast	Invasive ductal carcinoma	2	IIb	T2N1M0	–	–	Malignant
B2	10	F	38	Breast	Invasive ductal carcinoma	2	IIa	T2N0M0	–	++, 90%	Malignant
B3	11	F	37	Breast	Invasive ductal carcinoma	3	IIb	T3N1M0	–	–	Malignant
B4	12	F	59	Breast	Mixed lobular and duct carcinoma	–	IIb	T2N1M0	+++, 95%	+++, 100%	Malignant
B5	13	F	50	Breast	Invasive ductal carcinoma	2	IIb	T2N1M0	–	–	Malignant
B6	14	F	38	Breast	Invasive ductal carcinoma	2	IIa	T2N0M0	–	++, 90%	Malignant
B7	15	F	37	Breast	Invasive ductal carcinoma	3	IIb	T3N1M0	–	–	Malignant
B8	16	F	59	Breast	Mixed lobular and duct carcinoma	–	IIb	T2N1M0	+++, 95%	+++, 100%	Malignant
C1	17	F	41	Breast	Neuroendocrine carcinoma	–	–	–	–	–	Malignant
C2	18	F	52	Breast	Invasive lobular carcinoma	–	IIa	T2N0M0	++, 80%	+++, 99%	Malignant
C3	19	F	50	Breast	Nromal breast tissue	–	–	–	–	+, 10%	Normal
C4	20	F	18	Breast	Nromal breast tissue	–	–	–	–	–	Normal
C5	21	F	41	Breast	Neuroendocrine carcinoma	–	–	–	–	–	Malignant
C6	22	F	52	Breast	Invasive lobular carcinoma	–	IIa	T2N0M0	++, 80%	+++, 99%	Malignant
C7	23	F	50	Breast	Nromal breast tissue	–	–	–	–	+, 10%	Normal
C8	24	F	18	Breast	Nromal breast tissue	–	–	–	–	–	Normal
–	–	M	58	Skin	Malignant melanoma (tissue marker)	–					Malignant

† For precise diagnosis, refer to pathology description.

**The grade 1-3 (or I-III) in Pathology Diagnosis is equivalent to well-differentiated, moderately-differentiated or poorly differentiated, respectively, under microscope.
Grade 1 or well-differentiated: Cells appear normal and are not growing rapidly.
Grade 2 or moderately-differentiated: Cells appear slightly different than normal.
Grade 3 or poorly differentiated: Cells appear abnormal and tend to grow and spread more aggressively.
Grade 4 or undifferentiated: *(for certain tumors), features are not significantly distinguishing to make it look any different from undifferentiated cancers which occur in other organs.

Staining Scoring: "-" - no staining; "+-" - borderline staining; "+" - weak staining; "++" - moderate staining; "+++" - strong staining; "%" - percentage of positive cells.

TNM grading:

T - Primary tumor
Tx - Primary tumor cannot be assessed
T0 - No evidence of primary tumor
Tis - Carcinoma in situ; intraepithelial or invasion of lamina propria
T1 - Tumor invades submucosa
T2 - Tumor invades muscularis propria
T3 - Tumor invades through muscularis propria into subserosa or into non-peritonealized pericolic or perirectal tissues.
T4 - Tumor directly invades other organs or structures and/or perforate visceral peritoneum

N - Regional lymph nodes
Nx - Regional lymph nodes cannot be assessed
N0 - No regional lymph node metastasis
N1 - Metastasis in 1 to 3 regional lymph nodes
N2 - Metastasis in 4 or more regional lymph nodes

M - Distant metastasis
Mx - Distant metastasis cannot be assessed
M0 - No distant metastasis
M1 - Distant metastasis