US Biomax, Inc.

PM2-PR

PR Immunohistochemistry control tissue array, including TNM and pathology grade of breast cancer, 11 cases/11 cores

Microarray Panel:Progesterone Receptor(PR) IHC bio-marker control tissue microarray, for CAP proficiency test survey, containing 10 cases of breast invasive ductal carcinoma, containing Ki67 and Her-2 IHC results, single core per case
Cores:11
Cases:11
Layout:4 cols × 3 rows
Core Diameter:2 mm
Thickness:5 µm
Quality Control:Anti-Actin confirmed
Applications:Routine histology procedures including ImmunoHistochemistry (IHC) and In Situ Hybridization (ISH), protocols which can be found on our support page.
Notes:Unless specified, all TMA slides are not coated with extra layer of paraffin (tissue cores can be easily seen on the glass), so there is no need to bake, can be directly put into xylene for de-paraffin procedure.


Microarray Panel Display

 
Slide Label: US Biomax, Inc. Tissue Array
1234
A liv Bla Bre Bre
B Bre Bre Bre Bre
C Bre Bre Bre Bre
Legend: Bla - Blank, Bre - Breast, liv - liver

- Malignant tumor (stage IIIa), - Malignant tumor (stage IIIb), - Malignant tumor (stage IIa), - Malignant tumor (stage IIb)

Specification Sheet

Pos No. Sex Age Organ Pathology diagnosis Grade Stage TNM PR Ki67 HER2 Type †
A1 1 F 55 liver Hepatocellular liver cancer (tissue marker) 3 IIIa T3N0M0 Malignant
A2 2 Blank Blank
A3 3 F 35 Breast Invasive ductal carcinoma 1 IIIb T4N2M0 +++, 85% +++, 25% Malignant
A4 4 F 71 Breast Invasive ductal carcinoma 2 IIa T2N0M0 ++, 75% +++, 5% ++ Malignant
B1 5 F 56 Breast Invasive ductal carcinoma 1 IIb T2N1M0 ++, 50% +++, 8% Malignant
B2 6 F 47 Breast Invasive ductal carcinoma 1 IIb T3N0M0 +++, 90% +++, 7% Malignant
B3 7 F 48 Breast Invasive ductal carcinoma 2 IIb T2N1M0 ++, 45% +++, 45% Malignant
B4 8 F 45 Breast Invasive ductal carcinoma 2 IIa T2N0M0 ++, 25% +++, 45% + Malignant
C1 9 F 63 Breast Invasive ductal carcinoma 3 IIa T2N0M0 +++, 90% +++, 50% Malignant
C2 10 F 58 Breast Invasive ductal carcinoma 1 IIa T2N0M0 +++, 10% +++ Malignant
C3 11 F 53 Breast Invasive ductal carcinoma 1 IIa T2N0M0 +++, 25% +++ Malignant
C4 12 F 34 Breast Invasive ductal carcinoma 3 IIb T3N0M0 +++, 65% ++ Malignant

† For precise diagnosis, refer to pathology description.

**The grade 1-3 (or I-III) in Pathology Diagnosis is equivalent to well-differentiated, moderately-differentiated or poorly differentiated, respectively, under microscope.
Grade 1 or well-differentiated: Cells appear normal and are not growing rapidly.
Grade 2 or moderately-differentiated: Cells appear slightly different than normal.
Grade 3 or poorly differentiated: Cells appear abnormal and tend to grow and spread more aggressively.
Grade 4 or undifferentiated: *(for certain tumors), features are not significantly distinguishing to make it look any different from undifferentiated cancers which occur in other organs.

Staining Scoring: "-" - no staining; "+-" - borderline staining; "+" - weak staining; "++" - moderate staining; "+++" - strong staining; "%" - percentage of positive cells.

TNM grading:

T - Primary tumor
Tx - Primary tumor cannot be assessed
T0 - No evidence of primary tumor
Tis - Carcinoma in situ; intraepithelial or invasion of lamina propria
T1 - Tumor invades submucosa
T2 - Tumor invades muscularis propria
T3 - Tumor invades through muscularis propria into subserosa or into non-peritonealized pericolic or perirectal tissues.
T4 - Tumor directly invades other organs or structures and/or perforate visceral peritoneum

N - Regional lymph nodes
Nx - Regional lymph nodes cannot be assessed
N0 - No regional lymph node metastasis
N1 - Metastasis in 1 to 3 regional lymph nodes
N2 - Metastasis in 4 or more regional lymph nodes

M - Distant metastasis
Mx - Distant metastasis cannot be assessed
M0 - No distant metastasis
M1 - Distant metastasis

Find overlapping cases with this tissue array: