US Biomax, Inc.

BR082

Breast cancer tissue array with HER2 IHC control, including TNM and pathology grade, 4 cases/8 cores

Microarray Panel:Breast carcinoma tissue microarray, containing 4 cases of invasive ductal carcinoma, duplicate core per case
Cores:8
Cases:4
Layout:4 cols × 2 rows
Core Diameter:1.5 mm
Thickness:5 µm
Quality Control:Anti-Actin confirmed
Applications:Routine histology procedures including ImmunoHistochemistry (IHC) and In Situ Hybridization (ISH), protocols which can be found on our support page.
Notes:Unless specified, all TMA slides are not coated with extra layer of paraffin (tissue cores can be easily seen on the glass), so there is no need to bake, can be directly put into xylene for de-paraffin procedure.


Microarray Panel Display

 
Slide Label: US Biomax, Inc. Tissue Array
1234 
A Bre Bre Bre Bre  
B Bre Bre Bre Bre Marked point
Legend: Bre - Breast

- Malignant tumor, - Malignant tumor (stage IIIb), - Malignant tumor (stage IIa), - Malignant tumor (stage IIb)

Specification Sheet

Pos No. Sex Age Organ Pathology diagnosis Grade Stage TNM HER2 Type †
A1 1 F 58 Breast Invasive ductal carcinoma 3 IIa T2N0M0 3+ Malignant
A2 2 F 34 Breast Invasive ductal carcinoma 3 IIb T3N0M0 2+ Malignant
A3 3 F 46 Breast Invasive ductal carcinoma 2 IIIb T4N0M0 1+ Malignant
A4 4 F 57 Breast Invasive ductal carcinoma 3 IIb T3N0M0 0 Malignant
B1 5 F 58 Breast Invasive ductal carcinoma 3 IIa T2N0M0 3+ Malignant
B2 6 F 34 Breast Invasive ductal carcinoma 3 IIb T3N0M0 2+ Malignant
B3 7 F 46 Breast Invasive ductal carcinoma 2 IIIb T4N0M0 1+ Malignant
B4 8 F 57 Breast Invasive ductal carcinoma 3 IIb T3N0M0 0 Malignant
M 58 Skin Malignant melanoma (tissue marker) Malignant

† For precise diagnosis, refer to pathology description.

**The grade 1-3 (or I-III) in Pathology Diagnosis is equivalent to well-differentiated, moderately-differentiated or poorly differentiated, respectively, under microscope.
Grade 1 or well-differentiated: Cells appear normal and are not growing rapidly.
Grade 2 or moderately-differentiated: Cells appear slightly different than normal.
Grade 3 or poorly differentiated: Cells appear abnormal and tend to grow and spread more aggressively.
Grade 4 or undifferentiated: *(for certain tumors), features are not significantly distinguishing to make it look any different from undifferentiated cancers which occur in other organs.

Staining Scoring: "-" - no staining; "+-" - borderline staining; "+" - weak staining; "++" - moderate staining; "+++" - strong staining; "%" - percentage of positive cells.

TNM grading:

T - Primary tumor
Tx - Primary tumor cannot be assessed
T0 - No evidence of primary tumor
Tis - Carcinoma in situ; intraepithelial or invasion of lamina propria
T1 - Tumor invades submucosa
T2 - Tumor invades muscularis propria
T3 - Tumor invades through muscularis propria into subserosa or into non-peritonealized pericolic or perirectal tissues.
T4 - Tumor directly invades other organs or structures and/or perforate visceral peritoneum

N - Regional lymph nodes
Nx - Regional lymph nodes cannot be assessed
N0 - No regional lymph node metastasis
N1 - Metastasis in 1 to 3 regional lymph nodes
N2 - Metastasis in 4 or more regional lymph nodes

M - Distant metastasis
Mx - Distant metastasis cannot be assessed
M0 - No distant metastasis
M1 - Distant metastasis

Find overlapping cases with this tissue array: