US Biomax, Inc.

BM483c

Bone tumor and adjacent normal tissue array, including TNM and clinical stage, 24 cases/48 cores, replacing BM483b

Microarray Panel:Bone tumor and adjacent normal tissue microarray, containing 10 cases of myeloma, 1 each of primitive neuroectodermal tumor (PNET), ewing's sarcoma and B-cell lymphoma, 11 adjacent normal tissue, duplicate cores per case
Cores:48
Cases:24
Layout:8 cols × 6 rows
Core Diameter:1.5 mm
Thickness:5 µm
Applications:

Routine histology procedures including Immunohistochemistry (IHC) and In Situ Hybridization (ISH), protocols which can be found at our support page.

Notes:1. TMA slides were sectioned and stored at 4°C and may not be fresh cut, but still suitable for IHC. Please request fresh cut if experiment involves phospho-specific antibodies, RNA studies, FISH or ISH, etc. A minimum of 3 slides per TMA must be purchased to cover the cost of trimming for fresh sectioning.
2. Most of the TMA slides were not coated with an extra layer of paraffin (tissue cores can be easily seen on the glass). We still recommend 30 minutes of baking at 60°C before putting into xylene for de-paraffinization procedure.


Microarray Panel Display

 
Slide Label: US Biomax, Inc. Tissue Array
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A Bon Bon Bon Bon Bon Bon Bon Bon  
B Bon Bon Bon Bon Bon Bon Bon Bon  
C Bon Bon Bon Bon Bon Bon Bon Bon  
D Bon Bon Bon Bon Bon Bon Bon Bon  
E Bon Bon Bon Bon Bon Bon Bon Bon  
F Bon Bon Bon Bon Bon Bon Bon Bon Marked point
Legend: Bon - Bone

- Malignant tumor, - Malignant tumor (stage IB G2), - Malignant tumor (stage IIB G2), - NAT

Specification Sheet

Pos No. Sex Age Organ Pathology diagnosis Stage TNM Type †
A1 1 F 44 Bone Myeloma of right fourth rib Malignant
A2 2 F 44 Bone Myeloma of right fourth rib Malignant
A3 3 M 57 Bone Myeloma of sternum Malignant
A4 4 M 57 Bone Myeloma of sternum Malignant
A5 5 M 31 Bone Myeloma of left humerus Malignant
A6 6 M 31 Bone Myeloma of left humerus Malignant
A7 7 M 57 Bone Myeloma of right pubis Malignant
A8 8 M 57 Bone Myeloma of right pubis Malignant
B1 9 M 39 Bone Plasma cell myeloma of eighth thoracic vertebrae Malignant
B2 10 M 39 Bone Plasma cell myeloma of eighth thoracic vertebrae Malignant
B3 11 M 37 Bone Plasma cell myeloma of rib Malignant
B4 12 M 37 Bone Plasma cell myeloma of rib Malignant
B5 13 M 64 Bone Plasma cell myeloma of right ilium Malignant
B6 14 M 64 Bone Plasma cell myeloma of right ilium Malignant
B7 15 M 44 Bone Plasma cell myeloma of left third rib Malignant
B8 16 M 44 Bone Plasma cell myeloma of left third rib Malignant
C1 17 M 69 Bone Plasma cell myeloma of left clavicle Malignant
C2 18 M 69 Bone Plasma cell myeloma of left clavicle Malignant
C3 19 F 56 Bone Plasma cell myeloma of chest wall Malignant
C4 20 F 56 Bone Plasma cell myeloma of chest wall Malignant
C5 21 F 94 Bone Primitive neuroectodermal tumor (PNET) of right hip bone IB G2 T2N0M0 Malignant
C6 22 F 94 Bone Primitive neuroectodermal tumor (PNET) of right hip bone IB G2 T2N0M0 Malignant
C7 23 F 10 Bone Ewing's sarcoma of right femur (necrosis tissue) IIB G2 T2N0M0 Malignant
C8 24 F 10 Bone Ewing's sarcoma of right femur (sparse) IIB G2 T2N0M0 Malignant
D1 25 M 62 Bone Diffuse large B-cell lymphoma of right femur Malignant
D2 26 M 62 Bone Diffuse large B-cell lymphoma of right femur (necrosis tissue) Malignant
D3 27 F 50 Bone Adjacent normal bone marrow tissue NAT
D4 28 F 50 Bone Adjacent normal bone trabecula and bone marrow tissue NAT
D5 29 M 43 Bone marrow Adjacent normal bone marrow tissue NAT
D6 30 M 43 Bone marrow Adjacent normal bone marrow tissue NAT
D7 31 F 68 Bone Adjacent normal bone marrow tissue NAT
D8 32 F 68 Bone Adjacent normal bone trabecula and bone marrow tissue NAT
E1 33 M 41 Bone Adjacent normal bone marrow tissue NAT
E2 34 M 41 Bone Adjacent normal bone trabecula and bone marrow tissue NAT
E3 35 M 72 Bone Adjacent normal bone marrow tissue NAT
E4 36 M 72 Bone Adjacent normal bone trabecula and bone marrow tissue NAT
E5 37 F 66 Bone Adjacent normal bone trabecula and bone marrow tissue NAT
E6 38 F 66 Bone Adjacent normal bone trabecula and bone marrow tissue NAT
E7 39 M 63 Bone Adjacent normal bone trabecula and bone marrow tissue NAT
E8 40 M 63 Bone Adjacent normal bone trabecula and bone marrow tissue NAT
F1 41 F 43 Bone Adjacent normal bone trabecula and bone marrow tissue NAT
F2 42 F 43 Bone Adjacent normal bone trabecula and bone marrow tissue NAT
F3 43 M 75 Bone Adjacent normal bone trabecula and bone marrow tissue NAT
F4 44 M 75 Bone Adjacent normal bone trabecula and bone marrow tissue NAT
F5 45 M 58 Bone Adjacent normal bone trabecula and bone marrow tissue NAT
F6 46 M 58 Bone Adjacent normal bone trabecula and bone marrow tissue NAT
F7 47 M 62 Bone Adjacent normal bone trabecula and bone marrow tissue NAT
F8 48 M 62 Bone Adjacent normal bone trabecula and bone marrow tissue NAT

† For precise diagnosis, refer to pathology description.

TNM grading:

The American Joint Committee on Cancer (AJCC) TNM system Bone
TNM Definitions
T Primary Tumour
Tx Primary tumour cannot be assessed
T0 No evidence of primary tumour
T1 Tumour 8 cm or less in greatedt dimension
T2 Tumour more than 8 cm in greatest dimension
T3 Discontinuous tumours in the primary bone site

N Regional lymph Nodes
Nx Regional lymph nodes cannot be assessed
N0 No regional lymph node metastasis
N1 Regional lymph node metastasis

M Distant Metastasis
Mx Distant metastasis cannot be assessed
M0 No distant metastasis
M1 Distant metastasis
    M1a Lung
    M1b Other distant sites

Stage Groupings

Stage IA
    T1 N0,Nx M0 Low grade
Stage IB
    T2 N0,Nx M0 Low grade
Stage IIA
    T1 N0,Nx M0 Hight grade
Stage IIB
    T2 N0,Nx M0 Hight grade
Stage III
    T3 N0,Nx M0 Any grade
Stage IVA
    Any T N0 ,Nx M1a Any grade
Stage IVB
     Any T N1 Any M Any grade
     Any T Any N M1b Any grade


Find overlapping cases with this tissue array: